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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

ATP2B1 ATPase, Ca++ transporting, plasma membrane 1

PMCA
Top mentioned proteins: ATPase, CAN, PMCA4, SERCA, PrP
Papers using PMCA antibodies
Calcium signals: STIM dynamics mediate spatially unique oscillations
Supplier
Shin Dong Min et al., In The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2008
... Anti-PMCA (5F10) antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
Papers on PMCA
An improved method for expression and purification of functional human Ca(2+) transporter PMCA4b in Saccharomyces cerevisiae.
New
Mata et al., Badajoz, Spain. In Protein Expr Purif, Jan 2016
Here, using the yeast Saccharomyces cerevisiae system, we show a new and enhanced method for the expression of the full-length human PMCA isoform 4b (hPMCA4b) and a truncated form lacking its auto-inhibitory domain.
The Plasma Membrane Ca(2+) ATPase: Purification by Calmodulin Affinity Chromatography, and Reconstitution of the Purified Protein.
New
Carafoli et al., Bern, Switzerland. In Methods Mol Biol, Dec 2015
Plasma membrane Ca(2+) ATPases (PMCA pumps) are key regulators of cytosolic Ca(2+) in eukaryotes.
Characterization of Mesenchymal Stem Cells in sheep naturally infected with scrapie.
New
Martín-Burriel et al., Zaragoza, Spain. In J Gen Virol, Nov 2015
Despite the infectivity reported for MSCs obtained from scrapie infected mice and Creutzfeldt-Jakob-Disease patients, PMCA did not detect PrPSc in BM-MSCs nor in PB-MSCs from scrapie infected sheep, which limits their use as in vivo diagnosis for scrapie.
Protein misfolding cyclic amplification (PMCA): Current status and future directions.
Review
New
Cervenakova et al., Rockville, United States. In Virus Res, Oct 2015
These include the cell-free conversion assay, protein misfolding cyclic amplification (PMCA) and quaking induced conversion assay (QuIC), of which the PMCA has been the only technology shown to generate infectious prions.
The plethora of PMCA isoforms: Alternative splicing and differential expression.
Review
New
Krebs, Göttingen, Germany. In Biochim Biophys Acta, Sep 2015
In this review the four different genes of the mammalian plasma membrane calcium ATPase (PMCA) and their spliced isoforms are discussed with respect to their tissue distribution, their differences during development and their importance for regulating Ca²⁺ homeostasis under different conditions.
A mathematical model of the calcium transient in urinary bladder smooth muscle cells.
New
Manchanda et al., In Conf Proc Ieee Eng Med Biol Soc, Aug 2015
The plasma membrane Ca(2+)ATPase (PMCA) pump and sarco/endoplasmic reticulum Ca(2+)ATPase (SERCA) pump are responsible for lowering [Ca(2+)]i which leads to relaxation of smooth muscle.
Plasma membrane calcium ATPases: From generic Ca(2+) sump pumps to versatile systems for fine-tuning cellular Ca(2.).
Review
New
Strehler, Rochester, United States. In Biochem Biophys Res Commun, May 2015
The discovery of multiple PMCA isoforms and alternatively spliced variants cast doubt on this simplistic assumption, and revealed instead that PMCAs are integral components of highly regulated multi-protein complexes fulfilling specific roles in calcium-dependent signaling originating at the plasma membrane.
Molecular aspects of calcium signalling at the crossroads of unikont and bikont eukaryote evolution--the ciliated protozoan Paramecium in focus.
Review
New
Plattner, Konstanz, Germany. In Cell Calcium, Mar 2015
In addition Paramecium cells dispose of P-type Ca(2+)-ATPases, i.e. a plasmamembrane and a sarcoplasmic/endoplasmic reticulum Ca(2+)-ATPase (PMCA, SERCA).
Objects in Contact with Classical Scrapie Sheep Act as a Reservoir for Scrapie Transmission.
Simmons et al., Nottingham, United Kingdom. In Front Vet Sci, 2014
Sheep also became infected (20 out of 23) through exposure to contaminated field furniture placed within pasture not used by scrapie-infected sheep for 40 months, even though swabs from this furniture tested negative by PMCA.
Ionic homeostasis in brain conditioning.
Review
Pignataro et al., Napoli, Italy. In Front Neurosci, 2014
The present article will review the role of protein transporters and ionic channels involved in the control of ionic homeostasis in the neuroprotective effect of ischemic preconditioning and post-conditioning in adult brain, with particular regards to the Na(+)/Ca2(+) exchangers (NCX), the plasma membrane Ca2(+)-ATPase (PMCA), the Na(+)/H(+) exchange (NHE), the Na(+)/K(+)/2Cl(-) cotransport (NKCC) and the acid-sensing cation channels (ASIC).
Prions in the urine of patients with variant Creutzfeldt-Jakob disease.
Impact
Soto et al., Micronesia. In N Engl J Med, 2014
METHODS: To investigate whether PrP(Sc) can be detected in the urine of patients with variant Creutzfeldt-Jakob disease, we used the protein misfolding cyclic amplification (PMCA) technique to amplify minute quantities of PrP(Sc), enabling highly sensitive detection of the protein.
A bimodular mechanism of calcium control in eukaryotes.
Impact
Nissen et al., Århus, Denmark. In Nature, 2012
However, the structural basis for the activation mechanism is unknown and a key remaining question is how calmodulin-mediated PMCA regulation can cover both basal Ca(2+) levels in the nanomolar range as well as micromolar-range Ca(2+) transients generated by cell stimulation.
Estimating prion concentration in fluids and tissues by quantitative PMCA.
Impact
Soto et al., Houston, United States. In Nat Methods, 2010
Prions, the proteinaceous infectious agent responsible for prion diseases, can be detected with high sensitivity by protein misfolding cyclic amplification (PMCA) technology.
Calcium pumps in health and disease.
Review
Impact
Carafoli et al., Padova, Italy. In Physiol Rev, 2009
Two of the pumps have been known for decades (the SERCA and PMCA pumps); one (the SPCA pump) has only become known recently.
Crossing the species barrier by PrP(Sc) replication in vitro generates unique infectious prions.
Impact
Soto et al., Galveston, United States. In Cell, 2008
Here, we report the generation of infectious prions by interspecies transmission of PrP(Sc) misfolding by in vitro PMCA amplification.
Localization and regulation of plasma membrane Ca(2+)-ATPase in bovine spermatozoa.
GeneRIF
Wilhelm et al., Marburg an der Lahn, Germany. In Eur J Cell Biol, 2007
To demonstrate the subcellular localization and regulation of bovine sperm PMCA, cell fractionation, enzyme activity determination and Western blotting studies of PMCA in spermatozoa removed from the cauda epididymidis of bull, was performed.
Matrix metalloprotease 2-mediated activation of Ca(2+)-ATPase by superoxide radical (O2*-) in plasma membrane of bovine pulmonary vascular smooth muscle.
GeneRIF
Chakraborti et al., Kalyani, India. In Indian J Biochem Biophys, 2002
Adding pure bovine MMP-2 to the smooth muscle membrane suspension causes an increase in Ca(2+)-ATPase activity, but the pretreatment with TIMP-2 inhibits the increase in the enzyme activity
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