Curcumin Sensitizes Acute Promyelocytic Leukemia Cells to Unfolded Protein Response-induced Apoptosis by Blocking the Loss of Misfolded N-CoR Protein.
In PLoS ONE, 2010
... The AML-M5 cell lines, THP-1, Mono-Mac-1 (MM1), Nomo-1, MV-4-11, non-AML-M5 cell lines U937, HL-60, K562 and APL cell line NB4 were maintained in RPMI 1640 medium (Life Technologies, Gaithersburg, MD) supplemented with ...
Binding free energy estimation for protein-ligand complex based on MM-PBSA with various partial charge models.
Dalian, China. In Curr Pharm Des, 2012
The tested charges were calculated based on AM1 (Austin Method, version 1) - BCC (bond charge correction), MNDO (modified neglect of diatomic differential overlay), PM5 (Parameterisation Model, version 5), MUL (Mulliken), CM2 (Charge Model 2), CM3 (Charge Model 3), RESP (restrained electrostatic potential) and QM/MM (quantum mechanics/molecular mechanics) models.
Cellular functions of gamma-secretase-related proteins.
München, Germany. In Neurodegener Dis, 2005
We also identified and characterized the nicastrin-like protein nicalin which, together with the 130-kDa protein NOMO (Nodal modulator), forms a membrane protein complex different from gamma-secretase.