Myelin in Cartilaginous Fish.
Canada. In Brain Res, Feb 2016
And while they lack true proteolipid protein (PLP) like tetrapods, they express a DM-like protein in their myelin.
The Apicomplexan CDC/MACPF-like pore-forming proteins.
Oklahoma City, United States. In Curr Opin Microbiol, Aug 2015
Here we review recent studies that provide key insights into the assembly and regulation of the Apicomplexan PLP (ApiMACPF) molecular pore-forming mechanisms, which are necessary for the osmotically driven rupture of the parasitophorous vacuole and host cell membrane, and cell traversal by these parasites.
Clinical Forms and Animal Models of Hypophosphatasia.
Toulouse, France. In Subcell Biochem, 2014
TNAP substrates include inorganic pyrophosphate cleaved into inorganic phosphate (Pi) in bone, pyridoxal-5'-phosphate (PLP), the circulating form of vitamin B6, and phosphoethanolamine (PEA).
The influence of glutamatergic receptor antagonists on biochemical and ultrastructural changes in myelin membranes of rats subjected to experimental autoimmune encephalomyelitis.
Warsaw, Poland. In Folia Neuropathol, 2014
The aim of the study was to test the effects of the glutamatergic receptor antagonists amantadine and memantine (antagonists of NMDA receptors), LY 367384 (an antagonist of mGluR1), and MPEP (an mGluR5 antagonist) on the development of neurological symptoms in immunized animals, morphological changes in cerebral myelin, and expression of mRNA of the principal myelin proteins PLP, MBP, MOG, MAG, and CNPase.
Axon-glial signaling and the glial support of axon function.
Göttingen, Germany. In Annu Rev Neurosci, 2007
The underlying mechanisms are still poorly understood; we do know that to maintain axonal integrity, mammalian myelin-forming cells require the expression of some glia-specific proteins, including CNP, PLP, and MAG, as well as intact peroxisomes, none of which is necessary for myelin assembly.