The role of Plk3 in oncogenesis.
Frankfurt am Main, Germany. In Oncogene, May 2015
Plk1, which has been validated as a cancer target, came into the focus of many pharmaceutical companies for the development of small-molecule inhibitors as anticancer agents.
Understanding the Polo Kinase machine.
Montréal, Canada. In Oncogene, Feb 2015
In all organisms that contain Plks, one Plk family member fulfills several essential functions in the regulation of cell division, and here we refer to this conserved protein as Polo Kinase (Plk1 in humans).
Method: In vitro analysis of pericentriolar material assembly.
Dresden, Germany. In Methods Cell Biol, Dec 2014
Specifically, we describe (1) how to express and purify the C. elegans PCM proteins SPD-5, SPD-2, and PLK-1 from baculovirus-infected insect cells, (2) how to assemble these proteins into PCM-like structures in vitro, and (3) how to quantify this assembly process in a semiautomated fashion.
Role of NEK2A in human cancer and its therapeutic potentials.
More papers using
Guangzhou, China. In Biomed Res Int, Dec 2014
Additionally, critical roles in many aspects of cancer cell growth, proliferation, metastasis, and drug resistance have been assigned to some of these centrosomal kinases, such as polo-like kinase 1 (PLk1) and Aurora-A kinase.
Host-pathogen interactions: leukocyte phagocytosis and associated sequelae
In Cell Death & Disease, 2001
... anti-SR-A (clone SRA-E5, Trans Genic Inc., Kobe, Japan) and anti-LOX-1, anti-MARCO and anti-CD36 (clones 23C11, PLK1 and FA6-152, respectively, Cell Sciences, Canton, MA, USA) ...