This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011] (from
Gandley et al., Pittsburgh, United States. In Hypertension, 2012
Data suggest that identifying women with consistently low plasma placental growth factor (PGF) during pregnancy may provide a greater understanding of preeclampsia pathophysiology and may provide more focused research and clinical activities.
Spencer et al., United Kingdom. In Prenat Diagn, 2012
Although we have found no significant change in the second trimester levels of PlGF in trisomy 21 pregnancies, there remains wide disagreement within the literature on the behaviour of this marker during pregnancies of this syndrome.
Nardelli et al., Padova, Italy. In Clin Exp Obstet Gynecol, 2011
statistically significant decrease compared to physiological gestation in spontaneous and threatened abortions (p < 0.0001) and in ectopic pregnancies (p < 0.0001), and threatened premature delivery and uterine hypercontractility (p < 0.01)