Dietary fats significantly influence the survival of penumbral neurons in a rat model of chronic ischemic by modifying lipid mediators, inflammatory biomarkers, NOS production, and redox-dependent apoptotic signals.
La Plata, Argentina. In Nutrition, 30 Nov 2015
Homogenates and mitochondrial fractions were prepared from different zones and analyzed by redox status, inflammatory markers, ceramide, and arachidonate content, phospholipase A2, NOS, and proteases.
Tick-borne encephalitis - lipid peroxidation and its consequences.
Białystok, Poland. In Scand J Clin Lab Invest, 28 Oct 2015
Phospholipase A2 (PLA2), platelet-activating factor acetylhydrolase (PAF-AH) and glutathione peroxidase (GSH-Px) activities and vitamin E level were determined spectrophotometrically and by HPLC, respectively.
Secreted phospholipase A2 and mast cells.
Tokyo, Japan. In Allergol Int, Jan 2015
Among the PLA2 superfamily, secreted PLA2 (sPLA2) enzymes comprise the largest subfamily that includes 11 isoforms with a conserved His-Asp catalytic dyad.
HDL in infectious diseases and sepsis.
Cinisello Balsamo, Italy. In Handb Exp Pharmacol, Dec 2014
More importantly, endotoxemia modulates HDL composition and size: phospholipids are reduced as well as apolipoprotein (apo) A-I, while serum amyloid A (SAA) and secretory phospholipase A2 (sPLA2) dramatically increase, and, although the total HDL particle number does not change, a significant decrease in the number of small- and medium-size particles is observed.