Novel Genome-Editing Tools to Model and Correct Primary Immunodeficiencies.
Boston, United States. In Front Immunol, 2014
Severe combined immunodeficiency (SCID) and other severe non-SCID primary immunodeficiencies (non-SCID PID) can be treated by allogeneic hematopoietic stem cell (HSC) transplantation, but when histocompatibility leukocyte antigen-matched donors are lacking, this can be a high-risk procedure.
Human primary immunodeficiency diseases.
Paris, France. In Immunity, 2007
Primary immunodeficiency diseases (PID) provide invaluable insight into immune system, notably in vivo immune responses to microorganisms as based on the variable vulnerability to pathogens and opportunistic agents.