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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

RPTOR independent companion of MTOR, complex 2

Pia, P1A
RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: HAD, CAN, V1a, ACID, CD161
Papers using Pia antibodies
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity.
Basu Sujit, In PLoS ONE, 2000
... P1A transgenic (P1A Tg) mice were ...
pBBR 1 MCS: a broad-host-range cloning vector
Sumby Paul, In PLoS ONE, 1993
... ) were maintained on PIA plates (Pseudomonas Isolation Agar, Becton Dickinson, New Jersey, USA), supplemented ...
Papers on Pia
Inhibitory effects of Antibiofilm compound 1 in Staphylococcus aureus biofilms.
Sugai et al., Hiroshima, Japan. In Microbiol Immunol, Feb 2016
We demonstrated ABC-1 inhibits biofilm formation in these strains at micromolar concentrations regardless of the strains' dependence on Polysaccharide Intercellular Adhesin (PIA), cell wall-associated protein dependent or cell wall- associated extracellular DNA (eDNA).
Gene mutations of platelet glycoproteins and response to tirofiban in acute coronary syndrome.
Strunz et al., São Paulo, Brazil. In Sao Paulo Med J, Feb 2016
Glycoproteins Ia (807C/T ), Ib (Thr/Met) , IIb (Ile/Ser ) and IIIa (PIA ) were the mutations selected.
Magnetite/Polymer Brush Nanocomposites with Switchable Uptake Behavior Toward Methylene Blue.
Wilson et al., In Acs Appl Mater Interfaces, Feb 2016
UNASSIGNED: The grafting from approach was used to prepare pH-responsive polyacid brushes using poly (itaconic acid) (PIA) and poly (acrylic acid) (PAA) at the amine functional groups of chitosan.
Structure and Function of Surface Polysaccharides of Staphylococcus aureus.
Lee et al., Tübingen, Germany. In Curr Top Microbiol Immunol, Feb 2016
UNASSIGNED: The major surface polysaccharides of Staphylococcus aureus include the capsular polysaccharide (CP), cell wall teichoic acid (WTA), and polysaccharide intercellular adhesin/poly-β(1-6)-N-acetylglucosamine (PIA/PNAG).
Quantification of adenosine A1 receptor biased agonism: Implications for drug discovery.
May et al., Australia. In Biochem Pharmacol, Feb 2016
Subsequently, effects on cell survival and the bias profile of VCP746 and capadenoson were determined and compared to that of the prototypical A1AR agonists, NECA, R-PIA, MeCCPA and CPA.
AraC-type regulator Rsp adapts Staphylococcus aureus gene expression to acute infection.
Li et al., Shanghai, China. In Infect Immun, Jan 2016
Genome-wide transcriptional analysis and modeling of regulatory networks indicated that up-regulation of the accessory gene regulator (Agr) and down-regulation of the ica operon coding for the biofilm exopolysaccharide, polysaccharide intercellular adhesin (PIA), were central to the regulatory impact of Rsp on virulence.
The local effect of octreotide on mechanical pain sensitivity is more sensitive in DA rats than DA.1U rats.
Zhao et al., Greenville, United States. In Clin Exp Pharmacol Physiol, Dec 2015
The objective of present study was to investigate whether there was difference in the pristane-induced-arthritis (PIA) model and local analgesic effect of octreotide (OCT) between DA and DA.1U rats.
The syntaxin protein (MoSyn8) mediates intracellular trafficking to regulate conidiogenesis and pathogenicity of rice blast fungus.
Zhang et al., Nanjing, China. In New Phytol, Dec 2015
In addition, the ∆Mosyn8 mutant cannot elaborate biotrophic invasion of the susceptible rice host, or secrete avirulence factors Avr-Pia (corresponding to the rice resistance gene Pia) and Avrpiz-t (the cognate Avr gene for the resistance gene Piz-t) proteins.
Chromogranin A in gastrinomas: Promises and pitfalls.
Rehfeld, Copenhagen, Denmark. In Clin Chim Acta, Jul 2015
But the review suggests that CgA-quantitation using processing-independent analysis (PIA) may provide an equally high diagnostic sensitivity and in addition offer a simple possibility for estimation of the tumor-burden.
The potential of bacteriophage cocktail in eliminating Methicillin-resistant Staphylococcus aureus biofilms in terms of different extracellular matrices expressed by PIA, ciaA-D and FnBPA genes.
Bakar et al., Baghdad, Iraq. In Ann Clin Microbiol Antimicrob, 2014
METHOD: The resultant phage-based control was assessed in relation to the type of biofilm extracellular matrix namely, polysaccharide intercellular adhesion (PIA) or proteinacious fibronectin-binding protein A (FnBPA).
Polysaccharide intercellular adhesin in biofilm: structural and regulatory aspects.
Montanaro et al., Bologna, Italy. In Front Cell Infect Microbiol, 2014
The extracellular polymeric substances of staphylococcal biofilms are the polysaccharide intercellular adhesin (PIA), extracellular-DNA, proteins, and amyloid fibrils.
Methicillin resistance and the biofilm phenotype in Staphylococcus aureus.
O'Gara et al., Galway, Ireland. In Front Cell Infect Microbiol, 2014
Methicillin-sensitive S. aureus (MSSA) strains commonly produce an icaADBC operon-encoded polysaccharide intercellular adhesin (PIA)-dependent biofilm.
Clinical significance of proliferative inflammatory atrophy in prostate biopsy.
Morote et al., Barcelona, Spain. In Actas Urol Esp, 2014
INTRODUCTION: Proliferative inflammatory atrophy (PIA) is a frequently observed lesion in prostate biopsies and some authors have postulated its involvement in prostate carcinogenesis.
The diet as a cause of human prostate cancer.
Yegnasubramanian et al., Baltimore, United States. In Cancer Treat Res, 2013
This milieu appears to spawn proliferative inflammatory atrophy (PIA) lesions, a type of focal atrophy that represents the earliest of prostate cancer precursor lesions.
P1 and P2 protein heterodimer binding to the P0 protein of Saccharomyces cerevisiae is relatively non-specific and a source of ribosomal heterogeneity.
Ballesta et al., Madrid, Spain. In Nucleic Acids Res, 2012
The reported results support that while most ribosomes contain a P1alpha/P2beta-P0-P1beta/P2alpha structure in normal conditions, the stalk assembly mechanism can generate alternative compositions, which have been previously detected in the cell.
Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells.
Wang et al., Lexington, United States. In Biochem Biophys Res Commun, 2012
these results suggest that elevated growth factor signaling may contribute to decrease rictor/FBXW7-mediated ubiquitination of c-Myc and cyclin E, thus leading to accumulation of cyclin E and c-Myc in colorectal cancer cells.
From PTEN loss of expression to RICTOR role in smooth muscle differentiation: complex involvement of the mTOR pathway in leiomyosarcomas and pleomorphic sarcomas.
Aurias et al., Paris, France. In Mod Pathol, 2012
RICTOR overexpression in sarcomas and its links to therapeutic response need to be assessed
Multiple site acetylation of Rictor stimulates mammalian target of rapamycin complex 2 (mTORC2)-dependent phosphorylation of Akt protein.
Mayo et al., Charlottesville, United States. In J Biol Chem, 2012
multiple-site acetylation of Rictor signals for increased activation of mTORC2, providing a critical link between nutrient-sensitive deacetylases and mTORC2 signaling to Akt
Receptor-specific mechanisms regulate phosphorylation of AKT at Ser473: role of RICTOR in β1 integrin-mediated cell survival.
Johansson et al., Uppsala, Sweden. In Plos One, 2011
analysis of the role of RICTOR in beta1 integrin-mediated cell survival and how receptor-specific mechanisms regulate phosphorylation of AKT at Ser473
Pertussis toxin reverses adenosine inhibition of neuronal glutamate release.
Prestwich et al., In Nature, 1985
In an attempt to elucidate the mechanism of inhibition, we have examined the effect of pertussis toxin (PTX) on the ability of the stable adenosine analogue (-)phenylisopropyladenosine (PIA) to inhibit glutamate release from cerebellar neurones maintained in primary culture.
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