Novel regulation of cardiac Na pump via phospholemman.
London, United Kingdom. In J Mol Cell Cardiol, 2013
It is now widely recognized that phospholemman, a 72 amino acid accessory protein which forms part of the Na pump complex, is the key nexus linking cellular signaling to pump regulation.
Regulation of the cardiac sodium pump.
Dundee, United Kingdom. In Cell Mol Life Sci, 2013
The 72-residue phosphoprotein phospholemman regulates the sodium pump in the heart: unphosphorylated phospholemman inhibits the pump, and phospholemman phosphorylation increases pump activity.