Dysregulated glycolysis as an oncogenic event.
Kyoto, Japan. In Cell Mol Life Sci, May 2015
Furthermore, several regulators of glycolysis have been recently identified as oncogene candidates, including the hypoxia-inducible factor pathway, sirtuins, adenosine monophosphate-activated kinase, glycolytic pyruvate kinase M2, phosphoglycerate mutase, and oncometabolites.
Advances in the proteomic discovery of novel therapeutic targets in cancer.
Atlanta, United States. In Drug Des Devel Ther, 2012
A number of potential drug targets, such as baculoviral inhibitor of apoptosis protein repeat-containing protein 6, macrophage inhibitory cytokine 1, phosphoglycerate mutase 1, prohibitin 1, fascin, and pyruvate kinase isozyme 2 were identified in the proteomic analysis of drug-resistant cancer cells, drug action, and differential disease state tissues.