Sensing of latent EBV infection through exosomal transfer of 5'pppRNA.
Amsterdam, Netherlands. In Proc Natl Acad Sci U S A, Feb 2016
In ex vivo tonsillar cultures, we observed that EBER1-loaded exosomes are preferentially captured and internalized by human plasmacytoid DCs (pDCs) that express the TIM1 phosphatidylserine receptor, a known viral- and exosomal target.
The oxygenase Jmjd6--a case study in conflicting assignments.
München, Germany. In Biochem J, Jul 2015
The Jumonji domain-containing protein 6 (Jmjd6) is a member of the superfamily of non-haem iron(II) and 2-oxoglutarate (2OG)-dependent oxygenases; it plays an important developmental role in higher animals.
Interaction of JMJD6 with single-stranded RNA.
Denver, United States. In Proc Natl Acad Sci U S A, 2010
Data show that JMJD6 bound efficiently to single-stranded RNA, but not to single-stranded DNA, double-stranded RNA, or double-stranded DNA.
Engulfment is required for cell competition.
United States. In Cell, 2007
The engulfment genes draper, wasp, the phosphatidylserine receptor, mbc/dock180, and rac1 are needed in wild-type cells for the death of Minute neighbors, whose corpses are engulfed by wild-type cells.