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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

PERP, TP53 apoptosis effector

PERP, Thw, p53 apoptosis effector related to PMP-22
Top mentioned proteins: p53, HAD, p63, CAN, LRP
Papers on PERP
Techno-functional properties and in vitro bile acid-binding capacities of tamarillo (Solanum betaceum Cav.) hydrocolloids.
New
Muhammad et al., Kuala Selangor, Malaysia. In Food Chem, May 2016
The seed mucilage hydrocolloids that were extracted, using either 1% citric acid (THC) or water (THW), had a good foaming capacity (32-36%), whereas the pulp hydrocolloids that were extracted, using 72% ethanol (THE) or 20mM HEPES buffer (THH), had no foaming capacity.
Proprotein convertase subtilisin/kexin type 9 (PCSK9), soluble lectin-like oxidized LDL receptor 1 (sLOX-1) and ankle brachial index in patients with differentiated thyroid cancer.
New
Balos Toruner et al., Ankara, Turkey. In Endocr J, Jan 2016
We investigated proprotein convertase subtilisin/kexin type 9 (PCSK9), soluble lectin-like oxidized LDL receptor 1 (sLOX-1) and the ankle brachial index (ABI) in thyroid cancer patients with short-term overt hypothyroidism due to thyroid hormone withdrawal (THW).
Suppression of Her2/Neu mammary tumor development in mda-7/IL-24 transgenic mice.
New
Ben-David et al., Changchun, China. In Oncotarget, Dec 2015
Mechanistically, MDA-7/IL-24 exerted its tumor suppression effect on HER2+ breast cancer cells, at least in part, through PERP, a member of PMP-22 family with growth arrest and apoptosis-inducing capacity.
Obesity and intestinal epithelial deletion of the insulin receptor, but not the IGF 1 receptor, affect radiation-induced apoptosis in colon.
New
Lund et al., Chapel Hill, United States. In Am J Physiol Gastrointest Liver Physiol, Nov 2015
Levels of mRNAs encoding proapoptotic Perp and the cell cycle inhibitor Cdkn1b/p27 were reduced in CECs of obese mice and increased in lean mice lacking IR.
Novosphingobium aquaticum sp. nov., isolated from lake water in Suwon, Republic of Korea.
New
Yi et al., South Korea. In Antonie Van Leeuwenhoek, Oct 2015
A novel Gram-stain negative, yellow coloured, strictly aerobic, rod-shaped, non-motile bacterium designated as THW-SA1(T), was isolated from lake water near Samsung apartment, Suwon, Republic of Korea.
PERP, a host tetraspanning membrane protein, is required for Salmonella-induced inflammation.
New
McCormick et al., Worcester, United States. In Cell Microbiol, Jun 2015
Employing a split ubiquitin yeast-two-hybrid screen, we identified the tetraspanning membrane protein, p53 effector related to PMP-22 (PERP), as a SipA binding partner.
Muscular activation during plyometric exercises in 90° of glenohumeral joint abduction.
Bailie et al., Scottsdale, United States. In Sports Health, 2015
METHODS: Twenty healthy subjects were tested using surface EMG during the performance of 2 plyometric shoulder exercises: prone external rotation (PERP) and reverse catch external rotation (RCP) using a handheld medicine ball.
Ion homeostasis in a salt-secreting halophytic grass.
Agarwal et al., Bhāvnagar, India. In Aob Plants, 2014
Ex Thw.
Carryover effects of highly automated convoy driving on subsequent manual driving performance.
Huestegge et al., In Hum Factors, 2014
OBJECTIVE: In the present study, we tested to what extent highly automated convoy driving involving small spacing ("platooning") may affect time headway (THW) and standard deviation of lateral position (SDLP) during subsequent manual driving.
[Effects of telmisartan on inflammation and fibrosis after acute myocardial infarction in rats].
Zhang et al., Fushun, China. In Zhonghua Yi Xue Za Zhi, 2014
At the end of study, total heart weight (THW), left ventricular weight (LVW) and weight index were measured; myocardial infarction and inflammatory reactions detected by hematoxylin and eosin and Masson staining; the serum levels of C-reactive protein (CRP), tumor necrosis factor-alpha (TNFα), monocyte chemotactic protein-1 (MCP-1), interleukin-6 (IL-6) and interleukin-1 beta (IL-1β) by enzyme-linked immunosorbent assay (ELISA); the levels of transforming growth factor 1 (TGFβ1), collagen I, collagen III and MMP9 mRNA in myocardial tissue by reverse transcription-polymerase chain reaction (RT-PCR); the expressions of TGFβ1, collagen I, collagen III, matrix metallopeptidase 9 (MMP9) and nuclear factor-kappa B (NF-κB) by Western blot.
ERN1 knockdown modifies the hypoxic regulation of TP53, MDM2, USP7 and PERP gene expressions in U87 glioma cells.
Minchenko et al., In Ukr Biochem J, 2014
Glioma cells with ERN1 knockdown were used in order to investigate the effect of ERNI blockade on the expression of TP53, MDM2, PERP, and USP7 genes and its hypoxic regulation.
New insights into the pathogenesis of bladder exstrophy-epispadias complex.
Review
Cheng et al., Australia. In J Pediatr Urol, 2013
Furthermore, a Genome-Wide Expression Profiling (GWEP) study suggests possible involvement of PERP in human BEEC.
Pemphigus autoimmunity: hypotheses and realities.
Review
Grando, Irvine, United States. In Autoimmunity, 2012
Over 50 organ-specific and non-organ-specific antigens can be targeted by pemphigus autoimmunity, including desmosomal cadherins and other adhesion molecules, PERP cholinergic and other cell membrane (CM) receptors, and mitochondrial proteins.
Screening of three novel candidate genes in arrhythmogenic right ventricular cardiomyopathy.
GeneRIF
Svendsen et al., Copenhagen, Denmark. In Genet Test Mol Biomarkers, 2011
Our comprehensive mutation scanning did not identify any Arrhythmogenic right ventricular cardiomyopathy (ARVC) causing mutations.
PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.
GeneRIF
Klein et al., San Francisco, United States. In J Cell Sci, 2011
Data show that PERP is necessary for the integrity of the ameloblast-SI interface and that a lack of Perp causes downregulation of genes that are required for proper enamel formation.
PERP expression stabilizes active p53 via modulation of p53-MDM2 interaction in uveal melanoma cells.
GeneRIF
Paraoan et al., Liverpool, United Kingdom. In Cell Death Dis, 2010
PERP expression stabilizes active p53 via modulation of p53-MDM2 interaction in uveal melanoma cells.
Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis.
GeneRIF
Attardi et al., Stanford, United States. In Plos Genet, 2010
Studies suggest that Perp-deficiency promotes cancer by enhancing cell survival, desmosome loss, and inflammation, and they highlight a fundamental role for Perp and desmosomes in tumor suppression.
Differential PERP regulation by TP63 mutants provides insight into AEC pathogenesis.
GeneRIF
Attardi et al., Stanford, United States. In Am J Med Genet A, 2009
We demonstrate here that PERP induction is in fact compromised with some, but not all, Ankyloblepharon Ectodermal Dysplasia and Cleft Lip/Palate, AEC-patient derived TP63 mutants.
Gene expression profiling of localized esophageal carcinomas: association with pathologic response to preoperative chemoradiation.
Impact
Ajani et al., Houston, United States. In J Clin Oncol, 2006
Using a combination marker approach, levels of PERP, S100A2, and SPRR3 allowed discrimination of pathCR from < pathCR with high sensitivity and specificity (85%).
Perp is a p63-regulated gene essential for epithelial integrity.
Impact
GeneRIF
Attardi et al., Stanford, United States. In Cell, 2005
Perp is a key effector in the p63 developmental program.
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