Roles of Periostin in Respiratory Disorders.
Saga, Japan. In Am J Respir Crit Care Med, Feb 2016
In asthma, periostin is recognized as a biomarker of Type 2 inflammation; POSTN gene expression is upregulated in bronchial epithelial cells by interleukin-13 (IL-13) and IL-4.
Asthma control and exacerbations: two different sides of the same coin.
Belfast, United Kingdom. In Curr Opin Pulm Med, Jan 2016
Composite biomarker strategies using easily measured surrogate indicators of type-2 inflammation (such as fractional exhaled nitric oxide, blood eosinophil count and serum periostin levels) may predict exacerbation risk better but it is unclear if they can be used to adjust corticosteroid treatment.
Biomarkers and severe asthma: a critical appraisal.
Genova, Italy. In Clin Mol Allergy, 2014
In this review, we describe the biomarkers actually known in scientific literature and used in clinical practice for SA assessment and management: neutrophils, eosinophils, periostin, fractional exhaled nitric oxide, exhaled breath condensate and galectins.
The perivascular niche regulates breast tumour dormancy.
Berkeley, United States. In Nat Cell Biol, 2013
We confirmed this surprising result in dormancy models and in zebrafish, and identified active TGF-β1 and periostin as tumour-promoting factors derived from endothelial tip cells.