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TEM-1 hypothetical protein

Penicillinase, TEM-1, TEM-2
This gene encodes a Ras-related protein that enriched in striatum. The product of this gene binds to GTP and possesses intrinsic GTPase activity. The gene belongs to the Ras superfamily of small GTPases. The exact function of this gene is unknown, but most striatum-specific mRNAs characterized to date encode components of signal transduction cascades. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CTX, ACID, HAD, CAN, pFGE
Papers using Penicillinase antibodies
Risk factors for Staphylococcus aureus nasal carriage in residents of three nursing homes in Germany
Weusten Axel et al., In GMS Krankenhaushygiene interdisziplinär, 2005
... Penicillinase activity was detected using the BBL DrySlide Nitrocefin test (Becton Dickinson).
Amperometric pH-sensing biosensors for urea, penicillin, and oxalacetate
Adeloju Samuel B. et al., In Sensors (Basel, Switzerland), 1999
... Penicillinase ( from Bacillus Cereus was purchased from Sigma Aldrich (USA) and was used ...
Papers on Penicillinase
Addicting diverse bacteria to a noncanonical amino acid.
Ellington et al., Austin, United States. In Nat Chem Biol, Feb 2016
By reengineering TEM-1 β-lactamase to be dependent on a NCAA, we maintained bacterial NCAA dependence for hundreds of generations without escape.
KPC-Producing Klebsiella pneumoniae Isolates in Croatia: A Nationwide Survey.
Tambic Andrasevic et al., Zagreb, Croatia. In Microb Drug Resist, Jan 2016
Isolate with a unique PFGE pattern produced TEM-1, while others produced TEM-116.
Contribution of PBP3 Substitutions and TEM-1, TEM-15, and ROB-1 Beta-Lactamases to Cefotaxime Resistance in Haemophilus influenzae and Haemophilus parainfluenzae.
Nørskov-Lauritsen et al., Århus, Denmark. In Microb Drug Resist, Jan 2016
AIMS: To investigate the relative contributions of naturally occurring penicillin-binding protein 3 (PBP3) substitutions, and TEM-1, TEM-15, and ROB-1 beta-lactamases on resistance to a third-generation cephalosporin in Haemophilus influenzae and Haemophilus parainfluenzae.
Apramycin treatment affects selection and spread of a multidrug-resistant Escherichia coli strain able to colonize the human gut in the intestinal microbiota of pigs.
Olsen et al., Frederiksberg, Denmark. In Vet Res, Dec 2015
It carried resistance genes to apramycin/gentamicin, sulphonamide, tetracycline, hygromycin B, β-lactams and streptomycin [aac(3)-IV, sul2, tet(X), aph(4), bla TEM-1 and strA/B], with all but tet(X) located on the same conjugative plasmid.
Evolvability as a function of purifying selection in TEM-1 β-lactamase.
Ranganathan et al., Dallas, United States. In Cell, Mar 2015
Here, we analyze the fitness effects of all single mutations in TEM-1 β-lactamase (4,997 variants) under selection for the wild-type function (ampicillin resistance) and for a new function (cefotaxime resistance).
Identification of Extended-Spectrum β-Lactamases Escherichia coli Strains Isolated from Market Garden Products and Irrigation Water in Benin.
Baba-Moussa et al., Abomey-Calavi, Benin. In Biomed Res Int, 2014
The penicillinase producing E. coli carried blaTEM (67.50%), blaSHV (10%), and blaCTX-M (22.50%) genes.
Antimicrobial resistance in methicillin susceptible and methicillin resistant Staphylococcus pseudintermedius of canine origin: literature review from 1980 to 2013.
Nielsen et al., Frederiksberg, Denmark. In Vet Microbiol, 2014
Stratified by MSSP and MRSP, no significant increases in antimicrobial resistance were observed over time, except for the penicillinase-labile penicillins (penicillin and ampicillin) among MSSP.
Antibiotic consumption and antibiotic stewardship in Swedish hospitals.
Giske et al., Linköping, Sweden. In Ups J Med Sci, 2014
The consumption of cephalosporins has decreased, whereas that of most other drugs including piperacillin-tazobactam, carbapenems, and penicillinase-sensitive and -resistant penicillins has increased and replaced cephalosporins.
Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli.
Karlowsky et al., Winnipeg, Canada. In Drugs, 2014
Ceftolozane displays increased activity against Gram-negative bacilli, including those that harbor classical β-lactamases (e.g., TEM-1 and SHV-1), but, similar to other oxyimino-cephalosporins such as ceftazidime and ceftriaxone, it is compromised by extended-spectrum β-lactamases (ESBLs) and carbapenemases.
The role of core groups in the emergence and dissemination of antimicrobial-resistant N gonorrhoeae.
Lewis, Johannesburg, South Africa. In Sex Transm Infect, 2013
Sex workers and their clients were the most important core group driving the dissemination of penicillinase-producing N gonorrhoeae in the 1970s.
Rapid point-of-care detection of the tuberculosis pathogen using a BlaC-specific fluorogenic probe.
Rao et al., Stanford, United States. In Nat Chem, 2012
These probes showed an enhancement by 100-200 times in fluorescence emission on BlaC activation and a greater than 1,000-fold selectivity for BlaC over TEM-1 β-lactamase, an important factor in reducing false-positive diagnoses.
Striatum specific protein, Rhes regulates AKT pathway.
Kim et al., Philadelphia, United States. In Neurosci Lett, 2012
Rhes is a novel striatal regulator of the AKT-mediated pathway in the striatum.
ML302, a Novel Beta-lactamase (BLA) Inhibitor
Hodder et al., Bethesda, United States. In Unknown Journal, 2012
Various secondary assays were run to determine its dual potency (VIM-2 IC50 = 548 nM; IMP-1 IC50 = 3.02 μM) and class B selectivity (it was inactive in TEM-1 and AmpC beta-lactamase enzymatic assays).
Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.
Usiello et al., Baltimore, United States. In Nat Neurosci, 2012
Ths results of this study indicted that Rhes physiologically binds to and activates mTOR in the striatum and L-DOPA-induced dyskinesia.
False extended-spectrum {beta}-lactamase phenotype in clinical isolates of Escherichia coli associated with increased expression of OXA-1 or TEM-1 penicillinases and loss of porins.
Woodford et al., London, United Kingdom. In J Antimicrob Chemother, 2011
'cefpiromase' or 'cefepimase' phenotype of the clinical isolates non-susceptible to cefpirome and cefepime resulted from high expression of TEM-1 or OXA-1
Endosialin is expressed in high grade and advanced sarcomas: evidence from clinical specimens and preclinical modeling.
Teicher et al., Framingham, United States. In Int J Oncol, 2011
endosialin can be detected in advanced sarcoma
CD248 facilitates tumor growth via its cytoplasmic domain.
Conway et al., Belgium. In Bmc Cancer, 2010
The multiple pathways regulated by the cytoplasmic domain of CD248 highlight its potential as a therapeutic target to treat cancer.
Liebmann et al., In Science, 1945
It has been found that an anti-penicillinase immune serum can be produced, in rabbits by the use of purified penicillinase as the antigen.
Liebmann et al., In Science, 1945
(2) The presence of the penicillinase immune plasma protein in this mixture protects penicillin in vitro from destruction by penicillinase.
Perlstein et al., In Science, 1945
(1) Standardization of penicillinase has been made possible by the method for its assay.
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