Combination antiretroviral studies for patients with primary biliary cirrhosis.
Edmonton, Canada. In World J Gastroenterol, Feb 2016
Following the characterization of a human betaretrovirus in patients with primary biliary cirrhosis (PBC), pilot studies using antiretroviral therapy have been conducted as proof of principal to establish a link of virus with disease and with the eventual aim to find better adjunct therapies for patients unresponsive to ursodeoxycholic acid.
Farnesoid X receptor modulators (2011 - 2014): a patent review.
Napoli, Italy. In Expert Opin Ther Pat, 2014
Cholestasis might occur as a consequence of inborn metabolic errors and three major disorders, intra-hepatic cholestasis in pregnancy, primary biliary cirrhosis (PBC) and primary sclerosing cholangitis account for the vast majority of clinical cholestasis occurring in adulthood.