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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Solute carrier family 36

PAT-3, SLC36A3
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Top mentioned proteins: ACID, MIG2, INa, CAN, Actin
Papers using PAT-3 antibodies
Muscle cell attachment in Caenorhabditis elegans
Fox Michael A., In PLoS ONE, 1990
... pat-3 transgenic rescued lines used in ...
Papers on PAT-3
Persistent cell migration and adhesion rely on retrograde transport of β1 integrin.
Johannes et al., France. In Nat Cell Biol, Jan 2016
Here, we demonstrate that β1 integrin (known as PAT-3 in Caenorhabditis elegans), but not β3, is transported from the plasma membrane to the trans-Golgi network, to be resecreted in a polarized manner.
Robust Distal Tip Cell Pathfinding in the Face of Temperature Stress Is Ensured by Two Conserved microRNAS in Caenorhabditis elegans.
Ambros et al., Worcester, United States. In Genetics, Aug 2015
Furthermore, our results indicate that mir-34 and mir-83 may modulate the integrin signaling involved in distal tip cell migration by potentially targeting the GTPase cdc-42 and the beta-integrin pat-3.
PAR-6, but not E-cadherin and β-integrin, is necessary for epithelial polarization in C. elegans.
Mango et al., Boston, United States. In Dev Biol, Aug 2015
Loss of E-cadherin(HMR-1) in combination with β-integrin(PAT-3) had no impact on the onset or formation of the arcade cell epithelium, nor the epidermis or digestive tract.
B-LINK: a hemicentin, plakin, and integrin-dependent adhesion system that links tissues by connecting adjacent basement membranes.
Sherwood et al., Durham, United States. In Dev Cell, 2014
Through targeted screening, we identify the integrin-binding cytolinker plakin (VAB-10A) and integrin (INA-1/PAT-3) as key BM-BM linkage regulators: VAB-10A localizes to the AC-BM interface and tethers hemicentin to the AC while integrin promotes hemicentin punctae formation.
Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans.
Hengartner et al., Zürich, Switzerland. In Cell Death Differ, 2014
The formation of such halos depends on the integrins PAT-2/PAT-3, UNC-112 and the GEF protein UIG-1, but not on the canonical ced-1/6/7 or ced-2/5/12 signaling modules.
Suppressor mutations suggest a surface on PAT-4 (Integrin-linked Kinase) that interacts with UNC-112 (Kindlin).
Benian et al., Atlanta, United States. In J Biol Chem, 2014
The cytoplasmic tail of β-integrin (PAT-3) is associated with a conserved four-protein complex that includes UNC-112 (kindlin), PAT-4 (integrin-linked kinase), PAT-6 (α-parvin/actopaxin), and UNC-97 (PINCH).
MIG-10 (lamellipodin) has netrin-independent functions and is a FOS-1A transcriptional target during anchor cell invasion in C. elegans.
Sherwood et al., Durham, United States. In Development, 2014
Using the model of anchor cell (AC) invasion in C. elegans, we have previously shown that the integrin receptor heterodimer INA-1/PAT-3 promotes netrin receptor UNC-40 (DCC) localization to the invasive cell membrane of the AC.
α Integrin cytoplasmic tails have tissue-specific roles during C. elegans development.
Schwarzbauer et al., Newport News, United States. In Int J Dev Biol, 2013
C. elegans have two integrin heterodimers, α INA-1/β PAT-3 and α PAT-2/β PAT-3, which are expressed individually or simultaneously, based on tissue type.
Retromer subunits VPS35A and VPS29 mediate prevacuolar compartment (PVC) function in Arabidopsis.
Friml et al., Brno, Czech Republic. In Mol Plant, 2013
Here, we report the characterization of protein affected trafficking 3 (pat3) mutant that we identified by an epifluorescence-based forward genetic screen for mutants defective in subcellular distribution of Arabidopsis auxin transporter PIN1-GFP.
[Catalytic properties of enzymes from Erwinia carotovora involved in transamination of phenylpyruvate].
Sagian et al., In Prikl Biokhim Mikrobiol, 2013
Km for L-phenylalanine, L-glutamic acid, L-aspartic acid, and the corresponding keto acids were calculated, as well as Vmax, was measured for the following pairs of substrates: L-phenylalanine-2-ketoglutarate, L-phenylalanine-oxaloacetate, L-glutamic acid-phenylpyruvate, and L-aspartic acid-phenylpyruvate for aminotransferases PATI, PAT2, and PAT3 from Erwinia carotovora catalyzing transamination of phenylpyruvate.
A molecular mechanism for the requirement of PAT-4 (integrin-linked kinase (ILK)) for the localization of UNC-112 (Kindlin) to integrin adhesion sites.
Benian et al., Atlanta, United States. In J Biol Chem, 2012
PAT-3 (β-integrin), UNC-112 (kindlin), and PAT-4 (integrin-linked kinase) are associated with these structures.
A novel mutation in β integrin reveals an integrin-mediated interaction between the extracellular matrix and cki-1/p27KIP1.
Lee et al., Waco, United States. In Plos One, 2011
Here we demonstrate that the β integrin PAT-3 regulates the localization and expression of CKI-1, a C. elegans homologue of the cyclin dependent kinase inhibitor p27(KIP1).
The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport.
Anderson et al., Newcastle upon Tyne, United Kingdom. In Br J Pharmacol, 2011
SLC36A3 is expressed only in testes and is an orphan transporter with no known function.
Basement membrane sliding and targeted adhesion remodels tissue boundaries during uterine-vulval attachment in Caenorhabditis elegans.
Sherwood et al., Durham, United States. In Nat Cell Biol, 2011
Further, an RNA interference and expression screen identifies the integrin INA-1/PAT-3 and VAB-19, homologue of the tumour suppressor Kank, as regulators of basement membrane opening.
Mechanisms of lysophosphatidic acid (LPA) mediated stimulation of intestinal apical Cl-/OH- exchange.
Dudeja et al., Chicago, United States. In Am J Physiol Gastrointest Liver Physiol, 2010
lysophosphatidic acid stimulates apical Cl(-)/OH(-) exchange activity and surface levels of SLC36A3 and SLC26A6 in intestinal epithelial cells
Parthenocarpic fruit development in tomato.
Lindhout et al., Wageningen, Netherlands. In Plant Biol (stuttg), 2005
In tomato, three main sources of facultative parthenocarpy, pat, pat-2, pat-3/pat-4, are known to have potential applications in agriculture.
A cluster of proton/amino acid transporter genes in the human and mouse genomes.
Daniel et al., Freising, Germany. In Genomics, 2003
PAT3 was isolated and identified, but its function is not yet known.
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