Regulation of anoikis by Cdc42 and Rac1
In Journal of Signal Transduction, 2003
... -actin (mAb AC-40) (Sigma); Cdc42 (mAb-44) (BD Transduction Laboratories); pS144/141-PAK1/2 (mAb EP656Y) (Abcam); vinculin (mAb hVIN-1) (Abcam); ... E-cadherin engagement stimulates proliferation via Rac1more suppliers
In The Journal of Cell Biology, 2002
... SHE78-7 [Zymed Laboratories]; DECMA-1 [Sigma-Aldrich]); anti-p120 (98; BD Biosciences); anti–α-tubulin (Sigma-Aldrich); anti-GAPDH (Ambion); anti-Pak1/2/3 and anti–phospho-Pak1(Thr423)/Pak2(Thr402) (Cell Signaling Technology); and Y27632 (Calbiochem) ...
Governing effect of regulatory proteins for Cl(-)/HCO3(-) exchanger 2 activity.
Inch'ŏn, South Korea. In Channels (austin), Jan 2016
The main goal of the present study was to investigate potential regulators, such as spinophilin (SPL), inositol-1,4,5-trisphosphate [IP3] receptors binding protein released with IP3 (IRBIT), STE20/S;PS1-related proline/a;lanine-rich kinase (SPAK) kinase, and carbonic anhydrase XII (CA XII).
K-Cl cotransporters, cell volume homeostasis, and neurological disease.
Boston, United States. In Trends Mol Med, Aug 2015
Genetic models of certain KCCs, such as KCC3, and their inhibitory WNK-STE20/SPS1-related proline/alanine-rich kinase (SPAK) serine-threonine kinases, have demonstrated the evolutionary necessity of these molecules for nervous system cell volume regulation, structure, and function, and their involvement in neurological disease.
Endophilin marks and controls a clathrin-independent endocytic pathway.
Cambridge, United Kingdom. In Nature, Feb 2015
Here we show in mammalian cells that endophilin marks and controls a fast-acting tubulovesicular endocytic pathway that is independent of AP2 and clathrin, activated upon ligand binding to cargo receptors, inhibited by inhibitors of dynamin, Rac, phosphatidylinositol-3-OH kinase, PAK1 and actin polymerization, and activated upon Cdc42 inhibition.
Infectious Entry Pathway of Enterovirus B Species.
More papers using
Jyväskylä, Finland. In Viruses, 2014
Many cellular factors regulating the efficient entry have recently been associated with macropinocytic uptake, such as Rac1, serine/threonine p21-activated kinase (Pak1), actin, Na/H exchanger, phospholipace C (PLC) and protein kinase Cα (PKCα).