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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Platelet-activating factor acetylhydrolase 1b, catalytic subunit 2

Pafah1b2
Platelet-activating factor acetylhydrolase (PAFAH) inactivates platelet-activating factor (PAF) into acetate and LYSO-PAF. This gene encodes the beta subunit of PAFAH, the other subunits are alpha and gamma. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [providedby RefSeq, May 2010] (from NCBI)
Papers on Pafah1b2
Plasma platelet-activating factor-acetyl hydrolase activity and the levels of free forms of biomarker of lipid peroxidation in cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage.
GeneRIF
Yoshida et al., Sagamihara, Japan. In Neurosurgery, 2012
Plasma PAF-AH can hydrolyze oxidized phospholipids, and may attenuate the spreading of lipid peroxidation and participate in defense mechanisms against vasospasm after aneurysmal subarachnoid hemorrhage.
Intracellular erythrocyte platelet-activating factor acetylhydrolase I inactivates aspirin in blood.
GeneRIF
McIntyre et al., Cleveland, United States. In J Biol Chem, 2011
intracellular type I PAF acetylhydrolase (PAFAH1B2 and PAFAH1B3) is the major aspirin hydrolase of human blood
Opposing effects of Ndel1 and alpha1 or alpha2 on cytoplasmic dynein through competitive binding to Lis1.
GeneRIF
Zhu et al., Shanghai, China. In J Cell Sci, 2009
These results indicate an antagonistic effect of alpha1, alpha2 and Ndel1 for Lis1 binding, probably to modulate dynein functions in vivo.
Differential interaction of the Pafah1b alpha subunits with the Reelin transducer Dab1.
GeneRIF
D'Arcangelo et al., Houston, United States. In Brain Res, 2009
study examined biochemical interactions of Pafah1b Alpha1 & Alpha2 subunits with the Reelin signaling machinery & demonstrated that Alpha2, but not Alpha1, binds Dab1 in a phosphorylation-independent manner
Novel isoforms of intracellular platelet activating factor acetylhydrolase (PAFAH1b2) in human testis; encoded by alternatively spliced mRNAs.
GeneRIF
Bovill et al., Burlington, United States. In Prostaglandins Other Lipid Mediat, 2008
splice variants of the Pafah1b2 gene transcript retain exons 1-5 and replace exon 6 with alternative exons derived from genomic sequence 3' to exon 6. Splice variants encode two proteins with different novel carboxy termini
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