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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.


Top mentioned proteins: ACID, CAN, V1a, HAD, 1-Alkyl-2-acetylglycerophosphocholine Esterase
Papers using PAF antibodies
Novel human ocular glutathione S-transferases with high activity toward 4-hydroxynonenal
Chang Jason Y et al., In BMC Ophthalmology, 1994
... , azelaoyl PAF and ciglitazone were purchased from Cayman (Ann Arbor, MI) ...
Where freedom is given, liberties are taken.
Schneider David S., In PLoS Biology, 1994
... , U51605, AA (for ITC experiment), PAF, and SQ 29,548 were obtained from Cayman Chemical ...
Platelet-activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide
Shimizu Takao et al., In The Journal of Experimental Medicine, 1992
... or Toyobo (Kyoto, Japan); agaroses (Sea Kem and Nu Sieve) were from FMC (Rockland, ME); PAF (1- O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine) and leukotriene B4 (LTB4) were from Cayman Chemical (Ann Arbor, MI); ...
Use of WEB 2086 and WEB 2170 as platelet-activating factor antagonists
Johansen Berit et al., In Journal of Lipids, 1989
... Biologically active PAF C:16 and methyl arachidonyl fluorophosphonate (MAFP) were purchased from Cayman Chemical (USA) ...
Papers on PAF
PAFR in adipose tissue macrophages is associated with anti-inflammatory phenotype and metabolic homeostasis.
Rios et al., São Paulo, Brazil. In Clin Sci (lond), Feb 2016
The Platelet Activating Factor Receptor (PAFR) is expressed in several cell types and binds to PAF and oxidized phospholipids.
AChE inhibition-based multi-target-directed ligands, a novel pharmacological approach for the symptomatic and disease-modifying therapy of Alzheimer's disease.
Chen et al., Shanghai, China. In Curr Neuropharmacol, Feb 2016
Herein, we delineated the catalytic and non-catalytic functions of AChE, and summarized the works of our group and others in research and development of novel AChEI-based multi-target-directed ligands (MTDLs), such as dual binding site AChEIs and multi-target AChEIs inhibiting Aβ aggregation, regulating Aβ procession, antagonizing PAF receptor, scavenging oxygen radical, chelating metal ions, inhibiting MAO-B, blocking NMDA receptor and others.
The onset of lipid peroxidation in rheumatoid arthritis: consequences and monitoring.
Skrzydlewska et al., Białystok, Poland. In Free Radic Res, Feb 2016
Cytosolic phospholipase A2 (cPLA2), platelet-activating factor acetylhydrolase (PAF-AH) and glutathione peroxidase (GSH-Px) activities and vitamin E levels were also determined.
PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation.
Dynlacht et al., New York City, United States. In Plos Genet, Jan 2016
The PAF complex (Paf1C) has been shown to regulate chromatin modifications, gene transcription, and RNA polymerase II (PolII) elongation.
[Lp-PLA2, a biomarker of vascular inflammation and vulnerability of atherosclerosis plaques].
Bonnefont-Rousselot, Paris, France. In Ann Pharm Fr, Nov 2015
Among the emerging biomarkers of atherogenesis, the lipoprotein-associated phospholipase A2 (Lp-PLA2), formerly known as PAF-acetylhydrolase (McIntyre et al., 2009), hydrolyses the oxidized short chain phospholipids of low-density lipoproteins (LDL), thereby releasing pro-inflammatory mediators (lysophospholipids and oxidized fatty acids).
A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks.
Regev et al., Cambridge, United States. In Cell, Aug 2015
By measuring protein markers and mRNA profiles in DCs that are deficient in known or candidate genes, we classified the genes into three functional modules with distinct effects on the canonical responses to LPS and highlighted functions for the PAF complex and oligosaccharyltransferase (OST) complex.
Apolipoprotein M.
Yi et al., Hengyang, China. In Clin Chim Acta, Jul 2015
Multiple factors may influence its expression at both the post-transcriptional and the transcriptional levels both in vivo and ex vivo as follows: hepatocyte nuclear factor-1α, 4α (HNF-1α, 4α), liver receptor homolog-1 (LRH-1), forkhead box A2 (Foxa2) and platelet activating factor (PAF) upregulate its expression; liver X receptor (LXR), retinoid X receptor (RXR), farnesoid X receptor (FXR), small heterodimer partner (SHP) and the majority of cytokines downregulate its expression.
Ceramide in the regulation of eryptosis, the suicidal erythrocyte death.
Lang et al., Tübingen, Germany. In Apoptosis, May 2015
Mechanisms involved in the stimulation eryptosis include ceramide formation which may result from phospholipase A2 dependent formation of platelet activating factor (PAF) with PAF dependent stimulation of sphingomyelinases.
An emphasis on molecular mechanisms of anti-inflammatory effects and glucocorticoid resistance.
Patel et al., In J Complement Integr Med, Mar 2015
GC hampers the function of numerous inflammatory mediators such as cytokines, chemokines, adhesion molecules, arachidonic acid metabolites, release of platelet-activating factor (PAF), inflammatory peptides and enzyme modulation involved in the process of inflammation.
Platelet Activating Factor Enhances Synaptic Vesicle Exocytosis Via PKC, Elevated Intracellular Calcium, and Modulation of Synapsin 1 Dynamics and Phosphorylation.
Gelbard et al., Rochester, United States. In Front Cell Neurosci, 2014
Platelet activating factor (PAF) is an inflammatory phospholipid signaling molecule implicated in synaptic plasticity, learning and memory and neurotoxicity during neuroinflammation.
Role of mast cells in atherosclerosis: a classical inflammatory disease.
Conti et al., Cagliari, Italy. In Int J Immunopathol Pharmacol, 2014
Mast cells which accumulate in the human arterial intima and adventitia during atherosclerotic plaque progression, release vasoactive and angiogenic compounds, and pro-inflammatory mediators, such as arachidonic acid metabolites, histamine, cytokines/chemokines, platelet activating factor (PAF) and proteolytic enzymes.
Quantitative genetic-interaction mapping in mammalian cells.
Krogan et al., San Francisco, United States. In Nat Methods, 2013
By integrating GI and PPI data, we created a functional map of chromatin complexes in mouse fibroblasts, revealing that the PAF complex is a central player in the mammalian chromatin landscape.
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
Choudhary et al., Copenhagen, Denmark. In Nat Cell Biol, 2012
Our results uncover a critical role for PCNA-associated factor PAF15 (p15(PAF)/KIAA0101) ubiquitylation during DNA replication.
Overexpression of KIAA0101 predicts poor prognosis in primary lung cancer patients.
Kaji et al., Sapporo, Japan. In Lung Cancer, 2012
High-level KIAA0101 expression was observed in 33.9% (121 of 357 cases).
The Paf oncogene is essential for hematopoietic stem cell function and development.
Denzin et al., New York City, United States. In J Exp Med, 2011
Paf as a novel and essential regulator of early hematopoiesis.
KIAA0101 interacts with BRCA1 and regulates centrosome number.
Parvin et al., Columbus, United States. In Mol Cancer Res, 2011
This study identifies KIAA0101 as a protein important for breast tumorigenesis, and as this factor has been reported as a UV repair factor, it may link the UV damage response to centrosome control
Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate.
Elledge et al., Boston, United States. In Proc Natl Acad Sci U S A, 2011
Data indicate that PAF15 associates with PCNA, and depletion of PAF15 decreases the number of cells in S phase, suggesting a role for it in cell cycle regulation.
KIAA0101 is overexpressed, and promotes growth and invasion in adrenal cancer.
Kebebew et al., Bethesda, United States. In Plos One, 2010
Data supports that KIAA0101 is a marker of cellular proliferation, promotes growth and invasion, and is a good diagnostic marker for distinguishing benign from malignant adrenocortical neoplasm.
TIF1gamma controls erythroid cell fate by regulating transcription elongation.
Zon et al., Boston, United States. In Cell, 2010
By genetic studies in the zebrafish tif1gamma mutant moonshine we found that loss of function of Pol II-associated factors PAF or DSIF rescued erythroid gene transcription in tif1gamma-deficient animals.
The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis.
Hess et al., Ann Arbor, United States. In Cancer Cell, 2010
MLL is involved in chromosomal rearrangements that generate fusion proteins with deregulated transcriptional activity.
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