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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Adenylate cyclase activating polypeptide 1 receptor 1

PACAP-R, pituitary adenylate cyclase activating polypeptide receptor, PACAP type IA receptor, PACAP-r1
regulates neural precursor proliferation; mediates inhibitory signaling for Shh-induced cerebellar granule precursor cell proliferation [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: PACAP, Vasoactive Intestinal Peptide, POLYMERASE, Neuropeptide, Secretin
Papers on PACAP-R
PAC1hop, null and hip receptors mediate differential signaling through cyclic AMP and calcium leading to splice variant-specific gene induction in neural cells.
GeneRIF
Eiden et al., Bethesda, United States. In Peptides, 2011
PAC1hop, null and hip receptors mediate differential signaling through cyclic AMP and calcium leading to splice variant-specific gene induction in neural cells.
Stimulatory effect of pituitary adenylate-cyclase activating polypeptide (PACAP) and its PACAP type I receptor (PAC1R) on prolactin synthesis in rat pituitary somatolactotroph GH3 cells.
GeneRIF
Miyazaki et al., Izumo, Japan. In Mol Cell Endocrinol, 2011
pituitary adenylate-cyclase activating polypeptide and its type 1 receptor, functions as a stimulator of prolactin alone or with thyrotropin releasing hormone in prolactin producing cells
Presence of pituitary adenylate cyclase activating polypeptide and its type I receptor in the rat kidney.
GeneRIF
Szakaly et al., Pécs, Hungary. In Transplant Proc, 2011
PACAP and its type I receptor are endogenously present in the kidney.
Region-specific changes in the immunoreactivity of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors (VPAC2, and PAC1 receptor) in the aged rat brains.
GeneRIF
Joo et al., Seoul, South Korea. In Brain Res, 2010
Expression of pituitary adenylate cyclase-activating peptide 1 receptor (PAC1) is significantly increased in the brain of aged rats.
Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival.
GeneRIF
Braas et al., Burlington, United States. In J Biol Chem, 2010
PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways, which involves Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival
The presence and distribution of pituitary adenylate cyclase activating polypeptide and its receptor in the snail Helix pomatia.
Reglodi et al., Portugal. In Neuroscience, 2008
PACAP-like and pituitary adenylate cyclase activating polypeptide receptor (PAC1-R)-like immunoreactivity was abundant both in the CNS and the peripheral nervous system of the snail.
Immunomodulatory effects of Maxadilan and Phlebotomus papatasi sand fly salivary gland lysates on human primary in vitro immune responses.
Titus et al., Fort Collins, United States. In Parasite Immunol, 2003
Finally, we determined that Max interacts with human cells through at least the pituitary adenylate cyclase activating polypeptide receptor.
Maxadilan, the vasodilator/immunomodulator from Lutzomyia longipalpis sand fly saliva, stimulates haematopoiesis in mice.
Titus et al., Fort Collins, United States. In Parasite Immunol, 2002
Moreover, these effects of maxadilan are mediated through the interaction of maxadilan with the pituitary adenylate cyclase activating polypeptide receptor.
Pituitary adenylate cyclase-activating polypeptide (PACAP) is involved in melatonin release via the specific receptor PACAP-r1, but not in the circadian oscillator, in chick pineal cells.
Murakami et al., Miyazaki, Japan. In Brain Res, 2002
We investigated whether PACAP is involved in melatonin release and the circadian oscillation system in chick pineal cells, and if so, whether its effects are mediated by the PACAP-specific receptor (PACAP-r1) or the vasoactive intestinal polypeptide (VIP) receptor.
VPAC1 is a cellular neuroendocrine receptor expressed on T cells that actively facilitates productive HIV-1 infection.
Ma et al., Toronto, Canada. In Aids, 2002
OBJECTIVE: A lack of productive HIV-1 infection of Kit225 compared to Jurkat T cells, despite similar levels of CD4 and HIV-1 chemokine co-receptors, was found to correlate with the expression of vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor-1 (VPAC1).
Vasoactive intestinal peptide (VIP)/pituitary adenylate cyclase-activating peptide receptor subtypes in mouse calvarial osteoblasts: presence of VIP-2 receptors and differentiation-induced expression of VIP-1 receptors.
Lerner et al., Umeå, Sweden. In Endocrinology, 2001
Three distinct complementary DNAs for vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP) receptors have been cloned and designated VIP-1 receptor (VIP-1R), VIP-2 receptor (VIP-2R), and PACAP receptor (PACAP-R).
Progesterone receptor activation mediates LH-induced type-I pituitary adenylate cyclase activating polypeptide receptor (PAC(1)) gene expression in rat granulosa cells.
Park-Sarge et al., Lexington, United States. In Biochem Biophys Res Commun, 2000
We have previously reported that the pituitary adenylate cyclase activating polypeptide (PACAP) gene is regulated in ovarian granulosa cells by the autocrine and/or paracrine interaction between progesterone and its nuclear receptor progesterone receptor (PR).
Role of second extracellular loop in the function of human vasoactive intestinal polypeptide/pituitary adenylate cyclase activating polypeptide receptor 1 (hVPAC1R).
Fahrenkrug et al., Copenhagen, Denmark. In J Mol Neurosci, 2000
To elucidate the functional role of the second extracellular loop of human vasoactive intestinal polypeptide/pituitary adenylate cyclase-activating polypeptide (VIP/PACAP) receptor (hVPAC1R), surface expression, ligand binding, and receptor activation were analyzed.
Regulation of vasoactive intestinal peptide receptor expression in developing nervous systems.
Bruce et al., Columbus, United States. In Ann N Y Acad Sci, 1999
Three distinct receptor subtypes, with differing affinity for VIP, have been cloned and characterized as receptors 1 and 2 (VPAC1 and VPAC2) and pituitary adenylate cyclase activating polypeptide receptor (PAC1).
Regulation of pituitary adenylate cyclase activating polypeptide and its receptor type 1 after traumatic brain injury: comparison with brain-derived neurotrophic factor and the induction of neuronal cell death.
Lindholm et al., Uppsala, Sweden. In Neuroscience, 1999
In contrast, the messenger RNA levels encoding pituitary adenylate cyclase activating polypeptide receptor type 1 first decreased after trauma and were then normalized in the dentate gyrus.
Developmental regulation of pituitary adenylate cyclase activating polypeptide (PACAP) and its receptor 1 in rat brain: function of PACAP as a neurotrophic factor.
Review
Takei et al., Uppsala, Sweden. In Ann N Y Acad Sci, 1999
To function as a trophic factor PACAP and PACAP-R must be expressed in the nervous system during early development.
VIP and PACAP enhance IL-6 release and mRNA levels in resting peritoneal macrophages: in vitro and in vivo studies.
Gomariz et al., Madrid, Spain. In J Neuroimmunol, 1998
Both neuropeptides stimulate rapidly, specifically, and similarly the production of IL-6, exerting their action through two different receptor/signal transduction systems, i.e., primarily through the binding to VIP1/PACAP receptor followed by adenylate cyclase activation, and partially through the activation of protein kinase C following binding to PACAP-R.
Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide modulate endotoxin-induced IL-6 production by murine peritoneal macrophages.
Gomariz et al., Madrid, Spain. In J Leukoc Biol, 1998
The inhibition on LPS-induced IL-6 production is specific, presumably mediated through a subtype of the PACAP-R.
Functional and molecular expression of PACAP/VIP receptors in the rat retina.
Cavallaro et al., Catania, Italy. In Brain Res Mol Brain Res, 1998
Reverse transcription-PCR analysis in the rat retina detected both type-I (PACAP-R and PACAP-HOP splice variants) and type-II (VIP-I and -2) receptor-mRNAs.
Effect of pituitary adenylate cyclase-activating polypeptide (PACAP) on progestin biosynthesis in cultured granulosa cells from rat ovary and expression of mRNA encoding PACAP type IA receptor.
Kubo et al., Tsukuba, Japan. In J Reprod Fertil, 1998
The technique of reverse transcription and polymerase chain reaction with primers specific to PACAP type I receptor were used to demonstrate the expression of mRNA encoding PACAP type IA receptor in these cells.
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