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Adenylate cyclase activating polypeptide 1 receptor 1

PACAP-R, pituitary adenylate cyclase activating polypeptide receptor, PACAP type IA receptor, PACAP-r1
regulates neural precursor proliferation; mediates inhibitory signaling for Shh-induced cerebellar granule precursor cell proliferation [RGD, Feb 2006] (from NCBI)
Papers on PACAP-R
PAC1hop, null and hip receptors mediate differential signaling through cyclic AMP and calcium leading to splice variant-specific gene induction in neural cells.
GeneRIF
Eiden et al., Bethesda, United States. In Peptides, 2011
PAC1hop, null and hip receptors mediate differential signaling through cyclic AMP and calcium leading to splice variant-specific gene induction in neural cells.
Stimulatory effect of pituitary adenylate-cyclase activating polypeptide (PACAP) and its PACAP type I receptor (PAC1R) on prolactin synthesis in rat pituitary somatolactotroph GH3 cells.
GeneRIF
Miyazaki et al., Izumo, Japan. In Mol Cell Endocrinol, 2011
pituitary adenylate-cyclase activating polypeptide and its type 1 receptor, functions as a stimulator of prolactin alone or with thyrotropin releasing hormone in prolactin producing cells
Presence of pituitary adenylate cyclase activating polypeptide and its type I receptor in the rat kidney.
GeneRIF
Szakaly et al., Pécs, Hungary. In Transplant Proc, 2011
PACAP and its type I receptor are endogenously present in the kidney.
Region-specific changes in the immunoreactivity of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors (VPAC2, and PAC1 receptor) in the aged rat brains.
GeneRIF
Joo et al., Seoul, South Korea. In Brain Res, 2010
Expression of pituitary adenylate cyclase-activating peptide 1 receptor (PAC1) is significantly increased in the brain of aged rats.
Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival.
GeneRIF
Braas et al., Burlington, United States. In J Biol Chem, 2010
PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways, which involves Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival
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