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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Sialic acid binding Ig-like lectin 7

p75, Siglec-7
Top mentioned proteins: NTR, CAN, NGF, trkA, Brain-derived neurotrophic factor
Papers using p75 antibodies
Heterogeneous requirement of IkappaB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy
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Paleolog Ewa M et al., In Arthritis Research & Therapy, 2002
... other day intraperitoneally as follows: vehicle (sterile 0.85% physiological saline), murine soluble TNF receptor (murine p75 receptor dimer fused to murine IgG2a; soluble TNF receptor [sTNF-R]II) at 5 mg/kg, PPI-2458 at 1.5 mg/kg and indomethacin (Sigma Aldrich Co., Poole, UK) at ...
Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells.
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Piccirillo Ciriaco A., In PLoS ONE, 1996
... encephalomyocarditis virus (EMCV) internal ribosome entry site (IRES); 3) low-affinity human nerve growth factor receptor (p75 LNGFR, also known as CD271) cDNA (OriGene); 4) bovine growth hormone ...
Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation
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Fisher Elizabeth M. C. et al., In Disease Models & Mechanisms, 1996
... Expression of the low affinity neurotrophin receptor p75 in spinal motoneurons in a transgenic mouse model for amyotrophic ...
Defective Ca2+ channel clustering in axon terminals disturbs excitability in motoneurons in spinal muscular atrophy
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Sendtner Michael et al., In The Journal of Cell Biology, 1987
... trypsin, cells were triturated and cultured after enrichment by panning with antibodies against the mouse p75 neurotrophin receptor (Abcam).
Papers on p75
Impact of medication adherence on the effectiveness of deferasirox for the treatment of transfusional iron overload in myelodysplastic syndrome.
New
Sanjurjo-Saez et al., Madrid, Spain. In J Clin Pharm Ther, Feb 2016
The median (p25, p75) duration of treatment was 11 (3·0, 37·8) months.
Epithelial Nuclear Factor-x03BA;B Activation in Inflammatory Bowel Diseases and Colitis-Associated Carcinogenesis.
Review
New
Watanabe et al., In Digestion, Feb 2016
We and others had observed the increased expression of the type 2 receptor for tumor necrosis factor (TNFR2/TNFRSF1b/p75) in IBD models.
Low-energy Shock Wave Therapy Ameliorates Erectile Dysfunction in a Pelvic Neurovascular Injuries Rat Model.
New
Lue et al., San Francisco, United States. In J Sex Med, Jan 2016
Schwann cell activation-related markers including p-Erk1/2 and p75 were upregulated after LESW treatment.
Neurotrophins and B-cell malignancies.
Review
New
Gorman et al., Galway, Ireland. In Cell Mol Life Sci, Jan 2016
The p75(NTR) and Trk receptors can elicit signalling in response to the presence or absence of their corresponding neurotrophin ligands.
Chronic mild stress influences nerve growth factor through a matrix metalloproteinase-dependent mechanism.
New
Budziszewska et al., Kraków, Poland. In Psychoneuroendocrinology, Jan 2016
Additionally, the decreased level of m-NGF together with the increased level of pro-NGF can decrease TrkA-mediated neuronal survival signalling and enhance the action of pro-NGF on the p75(NTR) receptor, respectively, to evoke pro-apoptotic signalling.
Experimental and Clinical Advances in Immunotherapy Strategies for Spinal Cord Injury Target on MAIs and Their Receptors.
Review
New
Wang et al., Chongqing, China. In Curr Pharm Des, Jan 2016
Interestingly, these three structurally different inhibitors share two common receptors, Nogo-66 receptor (NgR) and paired immunoglobulin-like receptor B (PirB), and transduce the inhibitory signal into neurons via their complex combinant and co-receptors, such as p75 neurotrophin receptor (p75NTR), Nogo receptor-interacting protein 1 (LINGO-1), and TROY.
LEDGF/p75 Overexpression Attenuates Oxidative Stress-Induced Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 in Prostate Cancer.
New
Casiano et al., Loma Linda, United States. In Plos One, Dec 2015
LEDGF/p75, also known as the DFS70 autoantigen, is a stress transcription co-activator implicated in cancer, HIV-AIDS, and autoimmunity.
Update on the role of p75NTR in neurological disorders: A novel therapeutic target.
Review
New
Wang et al., Chongqing, China. In Biomed Pharmacother, Dec 2015
As a low-affinity neurotrophins receptor, p75 neurotrophin receptor (p75NTR) is a transmembrane receptor involved in a diverse array of cellular responses, including apoptosis, survival, neurite outgrowth, migration, and cell cycle arrest, which may be related to some neurological disorders, such as Alzheimer's disease (AD), schizophrenia, major depressive disorder (MDD), posttraumatic stress disorder (PTSD), amyotrophic lateral sclerosis (ALS), and Parkinson's disease (PD).
Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.
New
Impact
Feigon et al., Los Angeles, United States. In Science, Nov 2015
The p75-p45-p19 subcomplex is identified as another RPA-related complex, CST (CTC1-STN1-TEN1).
Targeting virus-host interactions of HIV replication.
Review
New
Debyser et al., Leuven, Belgium. In Curr Top Med Chem, Oct 2015
Furthermore, compounds developed as Integrase-LEDGF/p75 interaction inhibitors (LEDGINs) have advanced to early clinical trials.
Nuclear architecture dictates HIV-1 integration site selection.
New
Impact
Lusic et al., Trieste, Italy. In Nature, Jun 2015
Functional viral integrase and the presence of the cellular Nup153 and LEDGF/p75 integration cofactors are indispensable for the peripheral integration of the virus.
Cerebellar Expression of the Neurotrophin Receptor p75 in Naked-Ataxia Mutant Mouse.
Marzban et al., Winnipeg, Canada. In Int J Mol Sci, 2014
Studies have suggested that the p75 neurotrophin receptor (NTR) plays a role in Pc degeneration; thus, in this study, we investigated the p75NTR pattern and protein expression in the cerebellum of the nax mutant mouse.
Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.
Review
Impact
Massa et al., Stanford, United States. In Nat Rev Drug Discov, 2013
One strategy to overcome these limitations is to target individual neurotrophin receptors — such as tropomyosin receptor kinase A (TRKA), TRKB, TRKC, the p75 neurotrophin receptor or sortilin — with small-molecule ligands.
The architecture of Tetrahymena telomerase holoenzyme.
Impact
Feigon et al., Los Angeles, United States. In Nature, 2013
p50 has an unanticipated role as a hub between the RNP catalytic core, p75-p19-p45 subcomplex, and the DNA-binding Teb1.
The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia.
GeneRIF
Mavilio et al., Milano, Italy. In Blood, 2009
The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia.
Cardiovascular actions of neurotrophins.
Review
Impact
Emanueli et al., Bristol, United Kingdom. In Physiol Rev, 2009
Conversely, the neurotrophin low-affinity p75(NTR) receptor induces apoptosis of endothelial cells and vascular smooth muscle cells and impairs angiogenesis.
Differences in the constitutive and SIV infection induced expression of Siglecs by hematopoietic cells from non-human primates.
GeneRIF
Ansari et al., Atlanta, United States. In Cell Immunol, 2007
The species-specific differences in the expression expression of Siglecs in SIV infection was studied.
Analysis of the CD33-related siglec family reveals that Siglec-9 is an endocytic receptor expressed on subsets of acute myeloid leukemia cells and absent from normal hematopoietic progenitors.
GeneRIF
Crocker et al., Dundee, United Kingdom. In Leuk Res, 2007
The expression levels of Siglec-7 were detectable in bone marrow plasma from AML patients and serum from normal donors.
The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design.
GeneRIF
van Aalten et al., Dundee, United Kingdom. In Biochem J, 2006
structural analysis of siglec-7 in complex with sialosides
Probing sialic acid binding Ig-like lectins (siglecs) with sulfated oligosaccharides.
GeneRIF
Bovin et al., Moscow, Russia. In Biochemistry (mosc), 2006
Siglecs-7 did not interact with sulfate derivatives of LacNAc and sulfated oligosaccharides containing sialic acid.
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