Phlorofucofuroeckol A inhibits the LPS-stimulated iNOS and COX-2 expressions in macrophages via inhibition of NF-κB, Akt, and p38 MAPK
In Evidence-based Complementary and Alternative Medicine : eCAM, 2010
... Antibodies specific for iNOS, COX-2, p50, p65, IκB-α, p-IκB-α, and goat anti-rabbit IgG-FITC were obtained from Santa Cruz Biotechnology (CA, USA), while antibodies ... SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages.more suppliers
In Environmental Health Perspectives, 2009
... from Cell Signaling Technology (Beverly, MA, USA); Antibodies against COX-2, Jun-B, Jun-D, c-Fos, Fra-1, and p65 from Santa Cruz Biotechnology (Santa Cruz, CA, USA); ...
Neuroprotective Mechanism of Lycium barbarum Polysaccharides against Hippocampal-Dependent Spatial Memory Deficits in a Rat Model of Obstructive Sleep Apnea.
Hong Kong, Hong Kong. In Plos One, Dec 2014
In addition, redox-sensitive nuclear factor kappa B (NFКB) canonical pathway was activated with a translocation of NFКB members (p65, p50) and increased expression levels of NFКB-dependent inflammatory cytokines and mediator (TNFα, IL-1β, COX-2); also, a significantly elevated level of ER stress (GRP78/Bip, PERK, CHOP) and autophagic flux in the hypoxic group, leading to neuronal apoptosis in hippocampal subfields (DG, CA1, CA3).
The bacterial translation stress response.
München, Germany. In Fems Microbiol Rev, Nov 2014
For example, the stringent factor RelA interacts with the ribosome to generate ppGpp under nutrient deprivation, whereas a variety of factors have been identified that bind to the ribosome under unfavorable growth conditions to shut-down (RelE, pY, RMF, HPF and EttA) or re-program (MazF, EF4 and BipA) translation.
NF-κB signaling regulates myelination in the CNS.
More papers using
Freiburg, Germany. In Front Mol Neurosci, 2013
A key transcription factor involved in these processes is nuclear factor-κB (NF-κB), a hetero or homodimer of the Rel family of proteins, including p65, c-Rel, RelB, p50, and p52.
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney.
In PLoS ONE, 2009
... phospho-IκBα, p38-MAPK, phospho-p38-MAPK (Thr180/Tyr182), p44/42 MAPK, phospho-p44/42 MAPK, SAPK/JNK, phospho-SAPK/JNK (T183/Y185), Histone H3 and NFκB p65 were from Cell Signaling Technology (Beverly, MA, USA) ... Non-enzymatic glycation of bone collagen modifies osteoclastic activity and differention
In Arthritis Research & Therapy, 2006
... electrophoretic mobility shift assay (EMSA) the following were used: NFκB consensus and mutant oligonucleotides, anti-NFκB p65(A)X (Santa Cruz Biotech, Santa Cruz, CA, USA), T4 Polynucleotide Kinase and Reaction Buffer (New England Biolabs Inc., Ipswich, MA, USA), ... Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis.
In PLoS ONE, 2004
... p-Akt (Ser473), CREB, p-CREB (Ser133), ERK1/2, p-ERK1/2 (Thr 202/Tyr 204), NF-κB p65, p-p65 (Ser276) and p-p65 (Ser536) were purchased from Cell Signaling Technology, Inc ... Signaling pathways responsible for cancer cell invasion as targets for cancer therapy.
In PLoS ONE, 2003
... and anti-rabbit IgG-conjugated horseradish peroxidase, rabbit polyclonal antibodies specific for p-MEK, MEK, p-ERK, ERK, p-p65, p65, CCR5 siRNA, control siRNA, control shRNA plasmid, and CCL5 shRNA plasmid were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ... Mechanism of steroid action and resistance in inflammation: Corticoisteroids, eosinophils and bronchial epithelial cells: new insights into the resolution of inflammation in asthma
In Journal of Inflammation (London, England), 2002
... (Alexis, Lausen, Switzerland), CD95 monoclonal antibody (clone CH-11; Immunotech, Marseille, France), NF-kB p65 and acetyl-NF-kB p65 (Lys310) antibodies (Cell Signaling Technology, Inc., Danvers, USA), ... Rapid production of retroviruses for efficient gene delivery to mammalian cells using 293T cell-based systems.
In PLoS Pathogens, 2000
... (AC-74, Sigma), RIP1 (38, BD Transduction Laboratories), HA (16B12, Covance Inc.), HA (3F10, Roche), NF-κB p65 (F-6, Santa Cruz, or C22B4, Cell Signaling), LC3B (D11, Cell signaling), ... Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells.
In PLoS ONE, 2000
... the following sources: anti-mouse and anti-rabbit IgGs, Bcl-2, Bcl-xL, Bax, TRAIL, DR4, DR5, PPAR, NF-κB p65 antibodies were purchased from Santa Cruz Biotechnology (Santa Cruz, CA); p21, ... KLF2 Is a Novel Transcriptional Regulator of Endothelial Proinflammatory Activation
In The Journal of Experimental Medicine, 1995
... Antibodies recognizing VCAM-1, intercellular cell adhesion molecule (ICAM)-1, p50, p65, IκB-α, phospho–IκB-α, and α-HA were purchased from Santa Cruz Biotechnology, Inc., p300 antibody (Labvision), ...