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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Ribosomal protein S2

p56, S-4, RPS2, RPS4, RPS5
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S5P family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with mouse LLRep3. It is co-transcribed with the small nucleolar RNA gene U64, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Lck, CAN, ACID, Src, CD4
Papers using p56 antibodies
ClustalW and ClustalX version 2.0.
Supplier
Mackey David, In PLoS Pathogens, 2006
... rps4-1 (SAIL_519_B09) were described previously [15].Complemented srfr1-4 transgenic lines were generated by ...
Papers on p56
The plastomes of two species in the endoparasite genus Pilostyles (Apodanthaceae) each retain just five or six possibly functional genes.
New
Renner et al., München, Germany. In Genome Biol Evol, Jan 2016
Illumina and 454 data and Sanger re-sequencing yielded circularized plastomes of 11,348 and 15,167 bp length, with both species containing five possibly functional genes (accD, rps3, rps4, rrn16, rrn23) and two/three pseudogenes (rpoC2 in P. aethiopica and rpl2 and rps12 in both species; rps12 may be functional in P. hamiltonii).
Complete mitochondrial genome of Skeletonema marinoi (Mediophyceae, Bacillariophyta), a clonal chain forming diatom in the west coast of Korea.
New
Yang et al., Ansan, South Korea. In Mitochondrial Dna, Jan 2016
There are four cases of gene overlapping between neighboring genes, i.e., rrs-trnM, rps2-rps4, nad1-tatC, and rps11-trnY.
Leucine zipper motif in RRS1 is crucial for the regulation of Arabidopsis dual resistance protein complex RPS4/RRS1.
New
Narusaka et al., Okayama, Japan. In Sci Rep, Dec 2015
RPS4 is a typical Toll/interleukin 1 Receptor (TIR)-type NLR, whereas RRS1 is an atypical TIR-NLR that contains a leucine zipper (LZ) motif and a C-terminal WRKY domain.
A Plant Immune Receptor Detects Pathogen Effectors that Target WRKY Transcription Factors.
New
Impact
Jones et al., Palmerston North, New Zealand. In Cell, Jun 2015
The Arabidopsis RRS1-R NB-LRR protein carries a C-terminal WRKY DNA binding domain and forms a receptor complex with RPS4, another NB-LRR protein.
A receptor pair with an integrated decoy converts pathogen disabling of transcription factors to immunity.
New
Impact
Deslandes et al., France. In Cell, Jun 2015
The Arabidopsis-interacting NLR pair, RRS1-R with RPS4, confers resistance to different pathogens, including Ralstonia solanacearum bacteria expressing the acetyltransferase effector PopP2.
Reference genes for reverse transcription quantitative PCR in canine brain tissue.
Penning et al., Utrecht, Netherlands. In Bmc Res Notes, 2014
RESULTS: Following the minimum information for publication of quantitative real-time PCR experiments precise guidelines, the expression of ten frequently used reference genes, namely YWHAZ, HMBS, B2M, SDHA, GAPDH, HPRT, RPL13A, RPS5, RPS19 and GUSB was evaluated in seven brain regions (frontal lobe, parietal lobe, occipital lobe, temporal lobe, thalamus, hippocampus and cerebellum) and whole brain of healthy dogs.
Topological centrality-based identification of hub genes and pathways associated with acute viral respiratory infection in infants.
Zhao et al., Jinan, China. In Genet Mol Res, 2014
Six hub genes namely RPL6, RPL3, EEF1B2, RPL15, EEF1A1, and RPS2, which were identified based on the topological centrality measures, were evaluated further.
The long-term maintenance of a resistance polymorphism through diffuse interactions.
Impact
Bergelson et al., Chicago, United States. In Nature, 2014
The protein encoded by the R gene RPS5 recognizes an AvrPphB homologue (AvrPphB2) and exhibits a balanced polymorphism that has been maintained for over 2 million years (ref.
Structural basis for assembly and function of a heterodimeric plant immune receptor.
Impact
Jones et al., Brisbane, Australia. In Science, 2014
Crystal structures of the N-terminal Toll-interleukin-1 receptor/resistance (TIR) domains of RPS4 and RRS1, individually and as a heterodimeric complex (respectively at 2.05, 1.75, and 2.65 angstrom resolution), reveal a conserved TIR/TIR interaction interface.
Sequestosome1/p62: a regulator of redox-sensitive voltage-activated potassium channels, arterial remodeling, inflammation, and neurite outgrowth.
Review
Mann et al., Tsukuba, Japan. In Free Radic Biol Med, 2013
SQSTM1 implements these functions through physical interactions with different types of proteins including atypical PKCs, nonreceptor-type tyrosine kinase p56(Lck) (Lck), polyubiquitin, and autophagosomal factor LC3.
Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers.
Impact
Hung et al., Houston, United States. In Cancer Cell, 2013
Epidermal growth factor receptor (EGFR) initiates a signaling cascade that leads to DNA synthesis and cell proliferation, but its role in regulating DNA replication licensing is unclear.
Actin branches out to link pathogen perception and host gene regulation.
Review
Day et al., East Lansing, United States. In Plant Signal Behav, 2013
In total, our work has identified significant alterations in the expression of the resistance protein RPS5 in an ADF4 phosphorylation dependent manner.
Heterozygosity for the proteasomal Psmc1 ATPase is insufficient to cause neuropathology in mouse brain, but causes cell cycle defects in mouse embryonic fibroblasts.
GeneRIF
Bedford et al., Houston, United States. In Neurosci Lett, 2012
In Psmc1(+/-)primary mouse embryonic fibroblasts we found decreased PSMC1 protein expression, altered assembly of the 26S proteasome and G2/M cell cycle arrest.
Activation of a plant nucleotide binding-leucine rich repeat disease resistance protein by a modified self protein.
GeneRIF
Innes et al., Bloomington, United States. In Cell Microbiol, 2012
Activation of RPS5 did not require PBS1 kinase function, and thus RPS5 appears to sense a subtle conformational change in PBS1, rather than cleavage.
Identification of methylated proteins in the yeast small ribosomal subunit: a role for SPOUT methyltransferases in protein arginine methylation.
GeneRIF
McBride et al., Los Angeles, United States. In Biochemistry, 2012
Rps2 is substoichiometrically modified at arginine-10 posttranslationally by small ribosomal subunit Rmt1 methyltransferase.
Dietary zinc deficiency in rodents: effects on T-cell development, maturation and phenotypes.
Review
Taylor et al., Winnipeg, Canada. In Nutrients, 2012
This review will examine the interrelationships among the hypothalamus-pituitary-adrenal stress axis, p56(lck), and T-cell maturation in both zinc deficiency and responses during zinc repletion.
Chemistry and biology of fascaplysin, a potent marine-derived CDK-4 inhibitor.
Review
Vishwakarma et al., Jammu, India. In Mini Rev Med Chem, 2012
Among this chemical family, a sponge-derived bis-indole alkaloid fascaplysin (1) exhibited broad range of bioactivities including antibacterial, antifungal, antiviral, anti-HIV-1-RTase, p56 tyrosine kinase inhibition, antimalarial, anti-angiogenic, antiproliferative activity against numerous cancer cell lines, specific inhibition of cyclin-dependent kinase-4 (IC(50) 350 nM) and action as a DNA intercalator.
Structure-function analysis of the coiled-coil and leucine-rich repeat domains of the RPS5 disease resistance protein.
GeneRIF
Innes et al., Bloomington, United States. In Plant Physiol, 2012
The RPS5 leucine-rich repeat domain functions to suppress RPS5 activation in the absence of PBS1 cleavage and promotes RPS5 activation in its presence.
Abscisic acid deficiency antagonizes high-temperature inhibition of disease resistance through enhancing nuclear accumulation of resistance proteins SNC1 and RPS4 in Arabidopsis.
GeneRIF
Hua et al., Ithaca, United States. In Plant Cell, 2012
Abscisic acid deficiency promotes the activity and nuclear localization of RPS4 at higher temperatures.
Role of host factors in bacteriophage φ29 DNA replication.
Review
Salas et al., Madrid, Spain. In Adv Virus Res, 2011
Moreover, the φ29-encoded protein p56 inhibits host uracil-DNA glycosylase activity and has been proposed to be a defense mechanism developed by the phage to prevent the action of the base excision repair pathway if uracil residues arise in replicative intermediates.
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