Luteal P4 synthesis in early pregnant gilts after induction of estrus with PMSG/hCG.
Olsztyn, Poland. In Anim Reprod Sci, Feb 2016
Corpora lutea (CLs) were collected on days 10, 12 and 15 of pregnancy and analyzed for (1) the mRNA and protein expression of steroidogenic acute regulatory protein (StAR), cytochrome P450 family 11 subfamily A polypeptide 1 (CYP11A1), and 3β-hydroxysteroid dehydrogenase (3βHSD); (2) the tissue concentration of P4; and (3) the mRNA expression of luteinizing hormone receptor (LHR) and estrogen receptors (ESR1 and ESR2).
Congenital lipoid adrenal hyperplasia.
Kwangju, South Korea. In Ann Pediatr Endocrinol Metab, 2014
The cholesterol side-chain cleavage enzyme, P450scc (CYP11A1), plays an essential role converting cholesterol to pregnenolone.