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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 04 Mar 2015.

Peroxiredoxin 6

p29, DKK3
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: DKK1, HAD, ACID, SFRP1, CAN
Papers using p29 antibodies
Targeting the Wnt pathway in cancer: the emerging role of Dickkopf-3
Furukawa Takahisa et al., In Journal of Biomedicine and Biotechnology, 2011
... BAC-Dkk3-EGFP Transgenic Mouse ...
Papers on p29
Epigenetic Regulation of KLHL34 Predictive of Pathologic Response to Preoperative Chemoradiation Therapy in Rectal Cancer Patients.
Kim et al., Seoul, South Korea. In Int J Radiat Oncol Biol Phys, 01 Apr 2015
RESULTS: Genome-wide screening identified 7 hypermethylated CpG sites (DZIP1 cg24107021, DZIP1 cg26886381, ZEB1 cg04430381, DKK3 cg041006961, STL cg00991794, KLHL34 cg01828474, and ARHGAP6 cg07828380) associated with preoperative CRT responses.
Antitumor effect of conditioned media derived from murine MSCs and 5-aminolevulinic acid (5-ALA) mediated photodynamic therapy in breast cancer in vitro.
Majidzadeh-A et al., Tehrān, Iran. In Photodiagnosis Photodyn Ther, 23 Mar 2015
BACKGROUND: Mesenchymal stem cells are multi-potent progenitor cells that inhibit tumor growth by some ligands and releasing factors including TRAIL, DKK-1 and DKK-3.
Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: enhancement of cytotoxicity with epigenetic modulators.
Andersson et al., Houston, United States. In Exp Hematol, 19 Mar 2015
The observed DNA demethylating activity of Clad and Clo may complement DAC activity, increase demethylation of the gene promoters for the SFRP1, DKK3 and WIF1, and cause degradation of β-catenin in cells exposed to [Clad/Clo+Flu+Bu+DAC+Pano].
Dickkopf-3 Acts as a Modulator of B Cell Fate and Function.
Arnold et al., Heidelberg, Germany. In J Immunol, 11 Mar 2015
In this study, we demonstrated that absence of Dickkopf-3 (DKK3) led to changes in the composition of the B cell compartment, which were due to an altered development and maintenance program of B cells.
Despite differential gene expression profiles pediatric MDS derived mesenchymal stromal cells display functionality in vitro.
Ball et al., Leiden, Netherlands. In Stem Cell Res, 28 Feb 2015
RCC-MDS MSC expressed increased levels of DKK3, a protein associated with decreased apoptosis.
Dysregulated expression of dickkopfs for potential detection of hepatocellular carcinoma.
Lee et al., Hong Kong, Hong Kong. In Expert Rev Mol Diagn, Jun 2014
Although DKK1 offers potential for its use in HCC diagnosis this review will discuss the challenges facing DKK1 and also shed some light on recent developments on the remaining DKK family members: DKK2, DKK3 and DKK4.
Preactivation of human MSCs with TNF-α enhances tumor-suppressive activity.
Prockop et al., Temple, United States. In Cell Stem Cell, 2013
Also, activated hMSCs secreted DKK3 to suppress MDA cell cycling, leading to a decrease in β-catenin and cyclin D1/D3 and an increase in p21.
Deregulated Cdk5 activity is involved in inducing Alzheimer's disease.
Pant et al., Bethesda, United States. In Arch Med Res, 2012
Upon stress, p35 and p39 are cleaved by calpain resulting in truncated products as p25 and p29.
Expression of the Wnt antagonist Dickkopf-3 is associated with prognostic clinicopathologic characteristics and impairs proliferation and invasion in endometrial cancer.
Holcombe et al., Orange, United States. In Gynecol Oncol, 2012
Dkk3 gene expression is frequently downregulated in endometrial cancer, and is associated with poor prognostic clinicopathologic markers. Results identify a role for Dkk3 as a tumor suppressor in EC, affecting both proliferation and invasiveness.
Drp2 and periaxin form Cajal bands with dystroglycan but have distinct roles in Schwann cell growth.
Brophy et al., Edinburgh, United Kingdom. In J Neurosci, 2012
Cajal band appositions contain a dystroglycan complex that includes periaxin and dystrophin-related protein (Drp)2.
Phox activity of differentiated PLB-985 cells is enhanced, in an agonist specific manner, by the PLA2 activity of Prdx6-PLA2.
Ambruso et al., Denver, United States. In Eur J Immunol, 2012
(2) activity of Prdx6-PLA(2) in intact cells mediates its ability to enhance phox activity in response to fMLF
Overexpression of Dickkopf-3 induces apoptosis through mitochondrial pathway in human colon cancer.
Liu et al., Wuhan, China. In World J Gastroenterol, 2012
Dkk-3 overexpression induced apoptosis in human colon cancer possibly through the mitochondrial pathway. Dkk-3 may be involved in the Wnt/beta-catenin signaling pathways in colon cancer.
Targeting the Wnt pathway in cancer: the emerging role of Dickkopf-3.
Dahl et al., Maastricht, Netherlands. In Biochim Biophys Acta, 2012
Indeed, research in Wnt biology has recently provided numerous clues, and evidence is accumulating that the secreted Wnt antagonist Dickkopf-related protein 3 (Dkk-3) and its regulators may constitute interesting therapeutic targets in the most important human cancers.
BAC-Dkk3-EGFP transgenic mouse: an in vivo analytical tool for Dkk3 expression.
Furukawa et al., Suita, Japan. In J Biomed Biotechnol, 2011
The precise expression of the Dkk3 protein was examined by generating transgenic mice that express EGFP integrated into the Dkk3 gene in a bacterial artificial chromosome plasmid.
Musashi1: a stem cell marker no longer in search of a function.
Yin et al., Washington, D.C., United States. In Cell Cycle, 2008
This process was associated with increased secretion of the growth factor, PLF1 and inhibition of the secreted Wnt pathway inhibitor, DKK3.
Regulation of mammalian ciliary beating.
Salathe, Miami, United States. In Annu Rev Physiol, 2006
The cAMP-dependent phosphorylation of PKA's main target, originally described as p29 in Paramecium, seems to increase ciliary beat frequency (CBF) directly.
Lack of CpG island methylator phenotype defines a clinical subtype of T-cell acute lymphoblastic leukemia associated with good prognosis.
Torres et al., Córdoba, Spain. In J Clin Oncol, 2005
PATIENTS AND METHODS: Methylation-specific polymerase chain reaction was used to analyze methylation of the ADAMTS-1, ADAMTS-5, APAF-1, ASPP-1, CDH1, CDH13, DAPK, DIABLO, DKK-3, LATS-1, LATS-2, NES-1, p14, p15, p16, p57, p73, PARK-2, PTEN, sFRP1/2/4/5, SHP-1, SYK, TMS-1, and WIF-1 genes in samples from 50 consecutive T-ALL patients (19 children and 31 adults).
Nucleotide sequence of the Rasheed rat sarcoma virus oncogene: new mutations.
Heidecker et al., In Science, 1983
The oncogene (Ra-v-ras) encodes a 29,000-dalton (p29) transforming protein.
Monoclonal antibody identifies a new Ia-like (p29,34) polymorphic system linked to the HLA-D/DR region.
Pesando et al., In Nature, 1981
The Ia antigens of the mouse are the basis for the genetic control of the immune response.
Purification and structural characterisation of human HLA-linked B-cell antigens.
Strominger et al., In Nature, 1977
The human B cell-specific alloantigen which is closely linked genetically to HLA contains two non-covalently associated, sialogycoprotein subunits of molecular weight (MW) 29,000 (p29), and 34,000 (p34).
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