Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis.
Berlin, Germany. In Semin Immunopathol, Nov 2015
Gradients of cytokines and chemokines (CCR2, CXCR2, CXCR3/CXCR5 agonists; TNF/IL-10, IL-1/IFN-I), expression of activation/death markers on immune cells (TNF receptor 1, PD-1, IL-27 receptor) or abundance of enzymes [arginase-1, matrix metalloprotease (MMP)-1, MMP-8, MMP-9] drive genesis and progression of lesions.
IL-20 in rheumatoid arthritis.
Tainan City, Taiwan. In Drug Discov Today, Sep 2015
Anti-IL-20 antibody has paved the way to clinical trials aimed at blocking the pathogenic actions of IL-20 in rheumatoid arthritis.