Chalcones with electron-withdrawing and electron-donating substituents: Anticancer activity against TRAIL resistant cancer cells, structure-activity relationship analysis and regulation of apoptotic proteins.
Kuala Lumpur, Malaysia. In Eur J Med Chem, 03 Apr 2014
The results showed that 20 apoptotic markers (Bad, Bax, Bcl-2, Bcl-w, Bid, Bim, CD40, Fas, HSP27, IGF-1, IGFBP-4, IGFBP-5, Livin, p21, Survivin, sTNF-R2, TRAIL-R2, XIAP, caspase-3 and caspase-8) were either up regulated or down regulated.
Clock genes: Their role in colorectal cancer.
More papers using
Athens, Greece. In World J Gastroenterol, 28 Mar 2014
Recent data support that molecules such as CLOCK1, BMAL1 and PER and CRY proteins have various effects on c-Myc/p21 and Wnt/β-catenin pathways and influence multiple steps of DNA damage response playing a critical role in the preservation of genomic integrity in normal and cancer cells.
A dual role of p53 in the control of autophagy.
In PLoS ONE, 2007
... Primary antibodies, including p53, phospho-p53 (Ser15), phospho-p53 (Thr55), p21, sequestosome 1 (SQSTM1/p62), and survivin, were purchased from Santa Cruz Biotechnology, Santa Cruz, CA ... Complementary functions of ATM and H2AX in development and suppression of genomic instability
In DNA Repair, 2007
... , termed γ-H2AX, Cell Signaling Technology, Beverly, MA, USA); (vi) rabbit monoclonal anti-p21 Waf1/Cip1 antibody (12D1, Cell Signaling Technology, Beverly, MA, USA), ... Stopping ras in its tracks.
In PLoS ONE, 2006
... Mouse anti-pan-Ras (Ab-3) and mouse monoclonal anti-K-Ras antibodies (mAbs) were obtained from Calbiochem, rabbit anti-β-tubulin antibodies (Abs) from Santa Cruz Biotechnology, mouse anti-phospho-ERK Ab from ... The structure and regulation of vinculin
In Journal of Cellular Physiology, 2005
... ON), α5 integrin (WB: 1/1,000) (AB1928, Millipore, Temecula, CA), αV integrin (WB: 1/1,000) (AB1930, Millipore), p21 (WB: 1/2,000) (Santa Cruz Biotechnology, Inc.), p27 (WB: 1/2,000) ... Comparison of the effect of mitochondrial inhibitors on mitochondrial membrane potential in two different cell lines using flow cytometry and spectrofluorometry
In Cell Death & Disease, 2002
... Santa-Cruz, Le perray en Yvelines, France), anti-ATG5 (D1G9, Cell Signaling, Montigny le Bretonneux, France), anti-p21 Waf1/Cip1 (DCS60, Cell Signaling), anti-Raptor (24C12, Cell Signaling), ...