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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Fatty acid binding protein 1, liver

binds oleic acid and other hydrophobic ligands; may play a role in hepatocyte cell proliferation; may transport activated chemical carcinogens [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: p16, FABP, ACID, p53, CAN
Papers using P14 antibodies
Protein level of apolipoprotein E increased in human hepatocellular carcinoma
Gong Zhiyuan et al., In Disease Models & Mechanisms, 2005
... In vivo studies of liver-type fatty acid binding protein (L-FABP) gene expression in liver of transgenic zebrafish (Danio rerio) ...
Facile means for quantifying microRNA expression by real-time PCR.
Califano Andrea, In PLoS ONE, 2004
... TCR-LCMV-P14/TCR transgenic (specific for LCMV gp33-41) ...
Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
Murali-Krishna Kaja et al., In The Journal of Experimental Medicine, 2002
... P14 and OT-1 TCR transgenic mice that were on ...
PKCθ Signals Activation versus Tolerance In Vivo
Ohashi Pamela S. et al., In The Journal of Experimental Medicine, 2001
... The P14 TCR transgenic mouse line ( ...
A well-behaved electrostatic potential based method using charge restraints for deriving atomic charges: The RESP model
Subbaramaiah Kotha et al., In Journal of Medicinal Chemistry, 2001
... Polyclonal antisera to liver fatty acid binding protein (L-FABP) was from Abcam Inc ...
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Papers on P14
DNA methylation markers for oral pre-cancer progression: A critical review.
Rajaraman et al., Gurgaon, India. In Oral Oncol, Feb 2016
Hyper-methylated loci reported in three or more studies included p16, p14, MGMT and DAPK.
Interaction between the spliceosomal pre-mRNA branch site and U2 snRNP protein p14.
Greenbaum et al., In Biochemistry, Feb 2016
UNASSIGNED: We have probed the molecular basis of recognition between human spliceosomal U2 snRNP protein p14 and RNA targets representing the intron's branch site region.
(II) Physiological profiling of an endogenous peptide in the basal forebrain: age-related bioactivity and blockade with a novel modulator.
Greenfield et al., United Kingdom. In Neuropharmacology, Feb 2016
Here we show that (1) assemblies are site-specific in their activity profile with the cortex displaying a significantly more extensive network activity than the sub-cortical basal forebrain; (2) there is an age-dependency, in both cortical and sub-cortical sites, with the younger brain (p14 rats) exhibiting more conspicuous assemblies over space and time compared to their older counterparts (p35-40 rats).
Evaluation of hematologic composition in newborn C57/BL6 mice up to day 35.
McElroy et al., Iowa City, United States. In Vet Clin Pathol, Jan 2016
Blood samples were obtained via facial vein sampling at postnatal days 0 (p0), p7, p14, p21, p28, or young adulthood (p35).
Deregulated Lipid Sensing by Intestinal CD36 in Diet-Induced Hyperinsulinemic Obese Mouse Model.
Niot et al., Dijon, France. In Plos One, Dec 2015
These alterations reflected a delay in lipid induction of genes for key proteins of TRL formation (MTP, L-FABP) and blood clearance (ApoC2).
Molecular and Genomic Alterations in Glioblastoma Multiforme.
Tabernero et al., Coimbra, Portugal. In Am J Pathol, Jul 2015
Such genetic alterations target distinct combinations of the growth factor receptor-ras signaling pathways, as well as the phosphatidylinositol 3-kinase/phosphatase and tensin homolog/AKT, retinoblastoma/cyclin-dependent kinase (CDK) N2A-p16(INK4A), and TP53/mouse double minute (MDM) 2/MDM4/CDKN2A-p14(ARF) pathways, in cells that present features associated with key stages of normal neurogenesis and (normal) central nervous system cell types.
L-FABP: A novel biomarker of kidney disease.
Mou et al., Shanghai, China. In Clin Chim Acta, Jun 2015
Human liver-type fatty acid-binding protein (hL-FABP), which is found in both the normal and the diseased human kidney, has been observed to bind free fatty acids.
Assessment of Worldwide Acute Kidney Injury, Renal Angina and Epidemiology in Critically Ill Children (AWARE): A Prospective Study to Improve Diagnostic Precision.
Goldstein et al., Cincinnati, United States. In J Clin Trials, 2014
Urinary AKI biomarkers to be measured include: urinary neutrophil gelatinase lipocalin (NGAL), kidney injury molecule-1 (KIM-1), liver-type fatty acid binding protein (l-FABP), and interleukin-18 (IL-18).
A Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage Response.
Tang et al., Hamilton, Canada. In Biomolecules, 2014
The locus encodes the p16INK4A and p14/p19ARF tumor suppressors that function in the pRb and p53 pathways, respectively.
VIN usual type-from the past to the future.
Micheletti et al., Milano, Italy. In Ecancermedicalscience, 2014
Most uVIN lesions are positive at immunohistochemistry to p16(ink4a) and p14(arf), but negative to p53.
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma.
Bae et al., Ch'ŏngju, South Korea. In Cancer Cell, 2013
A functional genetic screen of a fly mutant library and molecular analysis in cultured cell lines revealed that Runx3 forms a complex with BRD2 in a K-Ras-dependent manner in the early phase of the cell cycle; this complex induces expression of p14(ARF)/p19(Arf) and p21(WAF/CIP).
Role of the gut in lipid homeostasis.
Davidson et al., Saint Louis, United States. In Physiol Rev, 2012
We review the pathways and genetic regulation of chylomicron assembly, the role of dominant restriction points such as microsomal triglyceride transfer protein and apolipoprotein B, and the role of CD36, l-FABP, and other proteins in formation of the prechylomicron complex.
PDX1 regulation of FABP1 and novel target genes in human intestinal epithelial Caco-2 cells.
Sibley et al., Stanford, United States. In Biochem Biophys Res Commun, 2012
PDX1 repression of FABP1, LCT, and SI suggests a role for PDX1 in patterning anterior intestinal development.
Two genetic variants in FABP1 and susceptibility to non-alcohol fatty liver disease in a Chinese population.
Lin et al., Fuzhou, China. In Gene, 2012
The present study suggests that genetic variations within FABP1 influence susceptibility to non-alcohol fatty liver disease.
Decreased body weight and hepatic steatosis with altered fatty acid ethanolamide metabolism in aged L-Fabp -/- mice.
Davidson et al., Saint Louis, United States. In J Lipid Res, 2012
Aged female L-Fabp-/- mice are protected against weight gain and hepatic steatosis.
Common variants of the liver fatty acid binding protein gene influence the risk of type 2 diabetes and insulin resistance in Spanish population.
Chaves et al., Valencia, Spain. In Plos One, 2011
Common variants of the liver fatty acid binding protein genes 1-4 influence the risk of type 2 diabetes and insulin resistance in Spanish population
[Effect of baicalin on liver fatty acid binding protein in oxidative stress model in vitro].
Gao et al., Beijing, China. In Zhonghua Gan Zang Bing Za Zhi, 2011
Baicalin was able to enhance both L-FABP expression and activity of intracellular SOD and GSH, and therefore protected hepatocytes from oxidative stress.
The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma.
Stiles et al., Boston, United States. In Cancer Cell, 2011
Resistance to genotoxic modalities in p53-positive gliomas is generally attributed to attenuation of p53 functions by mutations of other components within the p53 signaling axis, such as p14(Arf), MDM2, and ATM, but this explanation is not entirely satisfactory.
A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
Nakamura et al., Tokyo, Japan. In Nat Genet, 2010
By fine mapping, the SNP showing the strongest association was located in intron 16 of CDKN2BAS and was implicated in regulating the expression of p15, p16 and p14.
A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14.
Klein et al., Hannover, Germany. In Nat Med, 2007
Here, we describe a previously unknown human primary immunodeficiency disorder and provide evidence that the endosomal adaptor protein p14, previously characterized as confining mitogen-activated protein kinase (MAPK) signaling to late endosomes, is crucial for the function of neutrophils, B cells, cytotoxic T cells and melanocytes.
More papers using P14 antibodies
Dynamic Repositioning of CD4 and CD8 Genes during T Cell Development
Robey Ellen A. et al., In The Journal of Experimental Medicine, 2001
... ), P14 TCR transgenic RAG-2 ...
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
Malissen Marie et al., In The Journal of Experimental Medicine, 1999
... The P14 (line 327, reference 23) and H-Y 2425 αβ TCR transgenic lines were maintained on ...
Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels
von Andrian Ulrich H. et al., In The Journal of Experimental Medicine, 1999
... P14 transgenic mice, which express a TCR ...
Tumor Growth Enhances Cross-Presentation Leading to Limited T Cell Activation without Tolerance
Ohashi Pamela S. et al., In The Journal of Experimental Medicine, 1998
... ), and P14 TCR (33) transgenic lines were interbred to ...
Beta-galactoside-binding protein secreted by activated T cells inhibits antigen-induced proliferation of T cells
Ahmed Rafi et al., In The Journal of Experimental Medicine, 1997
... BALB/cByJ, C57BL/6J, and P14 LCMV TCR-transgenic mice ...
Altered thymic positive selection and intracellular signals in Cbl-deficient mice
Ohashi Pamela S. et al., In The Journal of Experimental Medicine, 1997
... P14 TCR–transgenic mice (327 line) express ...
Tumor-infiltrating lymphocytes exhibiting high ex vivo cytolytic activity fail to prevent murine melanoma tumor growth in vivo.
Fritz Jörg Hermann, In PLoS ONE, 1997
... The 2C and P14 TCR-transgenic mice were kindly obtained ...
Long-term CD4 Th1 and Th2 memory following acute lymphocytic choriomeningitis virus infection.
Koup Richard A., In PLoS Pathogens, 1997
... P14 TCR-transgenic mice specific for the ...
Dual T cell receptor β chain expression on human T lymphocytes
Malissen Marie et al., In The Journal of Experimental Medicine, 1994
... The P14 TCR-β transgenic mice (line 128) express ...
Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning
Bevan Michael J. et al., In The Journal of Experimental Medicine, 1988
... P14 mice express a transgenic TCR specific for p33 ...
Interferon-γ acts directly on CD8+ T cells to increase their abundance during virus infection
Whitton J. Lindsay et al., In The Journal of Experimental Medicine, 1986
... P14 TCR-transgenic mice specific for the ...
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