Molecular and Genomic Alterations in Glioblastoma Multiforme.
Coimbra, Portugal. In Am J Pathol, Jul 2015
Such genetic alterations target distinct combinations of the growth factor receptor-ras signaling pathways, as well as the phosphatidylinositol 3-kinase/phosphatase and tensin homolog/AKT, retinoblastoma/cyclin-dependent kinase (CDK) N2A-p16(INK4A), and TP53/mouse double minute (MDM) 2/MDM4/CDKN2A-p14(ARF) pathways, in cells that present features associated with key stages of normal neurogenesis and (normal) central nervous system cell types.
L-FABP: A novel biomarker of kidney disease.
Shanghai, China. In Clin Chim Acta, Jun 2015
Human liver-type fatty acid-binding protein (hL-FABP), which is found in both the normal and the diseased human kidney, has been observed to bind free fatty acids.
Role of the gut in lipid homeostasis.
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Saint Louis, United States. In Physiol Rev, 2012
We review the pathways and genetic regulation of chylomicron assembly, the role of dominant restriction points such as microsomal triglyceride transfer protein and apolipoprotein B, and the role of CD36, l-FABP, and other proteins in formation of the prechylomicron complex.