Platelet activation at the onset of human endotoxemia is undetectable in vivo.
Vienna, Austria. In Platelets, Feb 2016
Blood was drawn before, 10, 30 and 60 min after LPS challenge and platelet activation analyzed by flow cytometry (GPIIb/IIIa activation, surface CD62P and CD40L, intraplatelet reactive oxygen formation and platelet-leukocyte aggregates) and ELISA (sCD40L, sCD62P and CXCL4).
The diversity of platelet microparticles.
Québec, Canada. In Curr Opin Hematol, Sep 2015
Circulating microparticles originating from megakaryocytes are distinguished from those derived from activated platelets by the presence of CD62P, LAMP-1, and immunoreceptor-based activation motif receptors.
Emerging anti-inflammatory drugs for atherosclerosis.
New York City, United States. In Expert Opin Emerg Drugs, 2013
These include antioxidants, phospholipase A(2) inhibitors, leukotriene pathway inhibitors, CCL2-CCR2 pathway inhibitors, non-specific anti-inflammatory drugs (i.e., methotrexate), IL-1 inhibitors and p-selectin inhibitors.
[Selectins as adhesion molecules and potential therapeutic target].
More papers using
Tunisia. In Arch Inst Pasteur Tunis, 2010
There are three types of selectin: the L-selectin (CD62L), which is constitutively expressed by most leukocyte populations, the P-selectin (CD62P) is found on activated platelets and endothelial cells, and the E-selectin (CD62E) expressed by activated endothelial cells.