Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families.
Riyadh, Saudi Arabia. In Cell Rep, Feb 2015
This prescreening step led to the identification of 69 recessive genes not previously associated with disease, of which 33 are here described (SPDL1, TUBA3E, INO80, NID1, TSEN15, DMBX1, CLHC1, C12orf4, WDR93, ST7, MATN4, SEC24D, PCDHB4, PTPN23, TAF6, TBCK, FAM177A1, KIAA1109, MTSS1L, XIRP1, KCTD3, CHAF1B, ARV1, ISCA2, PTRH2, GEMIN4, MYOCD, PDPR, DPH1, NUP107, TMEM92, EPB41L4A, and FAM120AOS).
Pharmacokinetics and organ distribution of diarylheptanoid phytoestrogens from Curcuma comosa in rats.
Khon Kaen, Thailand. In J Nat Med, 2012
HPLC was used to measure the concentration of three major compounds, (6E)-1,7-diphenylhept-6-en-3-one (DPH1), (4E,6E)-1,7-diphenylhepta-4,6-dien-3-ol (DPH2), and (6E)-1,7-diphenylhept-6-en-3-ol (DPH3), which were found to be present in the blood and tissues and were subsequently used as markers.
OVCA1: tumor suppressor gene.
Taipei, Taiwan. In Curr Opin Genet Dev, 2005
OVCA1, also known as DPH2L1, is a tumor suppressor gene associated with ovarian carcinoma and other tumors.
Genetic factors in ovarian carcinoma.
Los Angeles, United States. In Curr Oncol Rep, 2001
Novel genes recently implicated in ovarian tumorigenesis are discussed, including NOEY2, OVCA1, and PIK3CA.