Human plasma protein N-glycosylation.
Leiden, Netherlands. In Glycoconj J, 10 Dec 2015
Thus, as the assessment of protein glycosylation is becoming a major element in clinical and biopharmaceutical research, this review aims to convey the current state of knowledge on the N-glycosylation of the major plasma glycoproteins alpha-1-acid glycoprotein, alpha-1-antitrypsin, alpha-1B-glycoprotein, alpha-2-HS-glycoprotein, alpha-2-macroglobulin, antithrombin-III, apolipoprotein B-100, apolipoprotein D, apolipoprotein F, beta-2-glycoprotein 1, ceruloplasmin, fibrinogen, immunoglobulin (Ig) A, IgG, IgM, haptoglobin, hemopexin, histidine-rich glycoprotein, kininogen-1, serotransferrin, vitronectin, and zinc-alpha-2-glycoprotein. In addition, the less abundant immunoglobulins D and E are included because of their major relevance in immunology and biopharmaceutical research.
Factors Impacting Unbound Vancomycin Concentrations in Different Patient Populations.
Leuven, Belgium. In Antimicrob Agents Chemother, 30 Nov 2015
The variables included in the model were patient age, ward, number of coadministered drugs with high protein binding, kidney function (estimated glomerular filtration rate [determined by Chronic Kidney Disease Epidemiology Collaboration formula]), alpha-1-acid glycoprotein, albumin, total bilirubin, IgA, IgM, urea, and total vancomycin concentrations.
Plasma Concentrations of Hepcidin in Anemic Zimbabwean Infants.
Baltimore, United States. In Plos One, Dec 2014
METHODS: We measured plasma hepcidin, ferritin, soluble transferrin receptor (sTfR), alpha-1-acid glycoprotein and C-reactive protein (CRP) by ELISA on archived plasma from 289 HIV-unexposed anemic or non-anemic Zimbabwean infants at ages 3 mo, 6 mo and 12 mo.
Use of biomarkers in the management of children with lupus.
Innsbruck, Austria. In Curr Rheumatol Rep, 2013
The most promising biomarkers in juvenile-onset SLE include cell-bound complement activation products, some genomic profiles, and urinary proteins such as neutrophil gelatinase-associated lipocalin, monocyte chemoattractant protein-1, and alpha-1-acid glycoprotein.
The urine proteome as a radiation biodosimeter.
Kansas City, United States. In Adv Exp Med Biol, 2012
Analysis of acute-phase response proteins and markers of acute kidney injury showed increased urinary levels of cystatin superfamily proteins and alpha-1-acid glycoprotein.
[Psychotropic medication of elderly patients].
Tokyo, Japan. In Nihon Rinsho, 2012
Drugs medicated for elderly patients show different pharmacokinetics from young patients, because of change in the makeup of bodies, decrease of albumin, increase of alpha-1-acid glycoprotein, hypofunction of metabolism, and excretion by aging.