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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Family with sequence similarity 3, member B

ORF9, FAM3B, PANDER, pancreatic derived factor
Papers on ORF9
Effect of PANDER in βTC6-cell lipoapoptosis and the protective role of exendin-4.
Yang et al., Fuzhou, China. In Biochem Biophys Res Commun, 2012
these results demonstrated that the JNK-mediated signaling mechanism of palmitic acid -induced beta-cell apoptosis involves up-regulated expression of PANDER and activation of caspase-3.
Upregulation of pancreatic derived factor (FAM3B) expression in pancreatic β-cells by MCP-1 (CCL2).
Le et al., Shanghai, China. In Mol Cell Endocrinol, 2011
Data suggest a new link between the endocrine and immune systems and provide useful information for further investigating the physiological functions of PANDER and its involvement in inflammation-related pancreatic disorders.
[Effects of glucagon-like peptide-1 on the free fatty acid-induced expression of pancreatic derived factor in cultured β-TC3 cell line].
Li et al., Guangzhou, China. In Zhonghua Yi Xue Za Zhi, 2011
Palmitic acid induces the expression of PANDER and the apoptosis of beta-TC3 cells while glucagon-like peptide-1 counteracts the above effects through an activation of Akt signaling.
Pancreatic-derived factor promotes lipogenesis in the mouse liver: role of the Forkhead box 1 signaling pathway.
Guan et al., Beijing, China. In Hepatology, 2011
PANDER promotes lipogenesis and compromises insulin signaling in the liver by increasing FOXO1 activity.
PANDER KO mice on high-fat diet are glucose intolerant yet resistant to fasting hyperglycemia and hyperinsulinemia.
Burkhardt et al., Philadelphia, United States. In Febs Lett, 2011
Findings further indicate PANDER impacts glycemic levels and may represent a potential but complicated therapeutic target.
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