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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Outer dense fiber of sperm tails 2

Odf2, ODF1, Cenexin
localized to both the cortex and medulla of outer dense fibers, specialized cytoskeletal components of the sperm tail; may interact with other outer dense fiber proteins via a leucine zipper [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CAN, fibrillin-1, HAD, OUT, Astrin
Papers using Odf2 antibodies
Functional dissection of Rab GTPases involved in primary cilium formation
Supplier
Barr Francis A. et al., In The Journal of Cell Biology, 2005
... Cenexin/ODF2 splice variants were amplified from testis and fetal cDNA (CLONTECH Laboratories, Inc.) and subcloned ...
Papers on Odf2
Triosephosphate isomerase (TPI) and epididymal secretory glutathione peroxidase (GPX5) are markers for boar sperm quality.
New
Yeste et al., Girona, Spain. In Anim Reprod Sci, Feb 2016
The present study sought to determine the relationship of three sperm proteins (acrosin binding protein, ACRBP; outer dense fibre protein 1, ODF1; and triosephosphate isomerase, TPI), and two seminal plasma proteins (fibronectin, FN1; and epididymal secretory glutathione peroxidase, GPX5) to conventional sperm quality parameters (sperm membrane integrity, morphology and motility) in pigs.
Proteomic signatures of infertile men with clinical varicocele and their validation studies reveal mitochondrial dysfunction leading to infertility.
New
Sabanegh et al., Cleveland, United States. In Asian J Androl, Jan 2016
Expression levels of 5 key proteins (PKAR1A, AK7, CCT6B, HSPA2, and ODF2) involved in stress response and sperm function including molecular chaperones were validated by Western blotting.
Differences between high- and low-motility buffalo sperm identified by comparative proteomics.
New
Zhang et al., Nanning, China. In Reprod Domest Anim, Jun 2015
Finally, four proteins were successfully identified by MS as belonging to three unique proteins; they are outer dense fibre of sperm tails protein 2 (ODF2), ATP synthase subunit alpha (ATP5A1) and succinyl-CoA synthetase subunit beta (SUCLG2).
High-resolution 400K oligonucleotide array comparative genomic hybridization analysis of neurofibromatosis type 1-associated cutaneous neurofibromas.
New
Hosokawa et al., Japan. In Gene, Apr 2015
(56%, NLP) and gain of 2p23.3 (76%, C2orf53), 8q22.3 (44%, ODF1) and 8q24.3 (67%, ARC).
Identification of new susceptibility loci for IgA nephropathy in Han Chinese.
Liu et al., Guangzhou, China. In Nat Commun, 2014
(rs2074038, OR=1.14, P=3.93 × 10(-9)) and ODF1-KLF10 on 8q22.3 (rs2033562, OR=1.13,
Haplo-deficiency of ODF1/HSPB10 in mouse sperm causes relaxation of head-to-tail linkage.
Hoyer-Fender et al., Gießen, Germany. In Reproduction, 2014
The small heat shock protein ODF1/HSPB10 is essential for male fertility in mice.
High throughput quantitative reverse transcription PCR assays revealing over-expression of cancer testis antigen genes in multiple myeloma stem cell-like side population cells.
Chang et al., Houston, United States. In Br J Haematol, 2014
In the three MM cell lines tested, six CTA genes were over-expressed in two and LUZP4 and ODF1 were universally up-regulated in all three cell lines.
Relationship of sperm small heat-shock protein 10 and voltage-dependent anion channel 2 with semen freezability in boars.
Bonet et al., Girona, Spain. In Theriogenology, 2014
In this context, the present study sought to determine whether the amounts of small heat-shock protein 10 (also known as outer dense fiber protein 1) (ODF1/HSPB10) and voltage-dependent anion channel 2 (VDAC2) may be used as boar sperm freezability markers.
Mammalian Fused is essential for sperm head shaping and periaxonemal structure formation during spermatogenesis.
Chuang et al., San Francisco, United States. In Dev Biol, 2014
In addition, Fu interacts with the outer dense fiber protein Odf1, a major component of the periaxonemal structures in the sperm flagellum, and Kif27, which is detected in the manchette.
[Molecular genetic mechanisms of teratozoospermia].
Review
Wang et al., Changchun, China. In Zhonghua Nan Ke Xue, 2013
Aiming to provide some evidence for the pathogenesis of teratozoospermia, this paper reviews the relevant literature in the past five years addressing such special teratozoospermia as globozoospermia, nuclear vacuoles, decapitated spermatozoa, excessive residual cytoplasm, dysplasia of the fibrous sheath, and primary ciliary dyskinesia, and elaborates on the molecular genetic mechanisms of DPY19L2, AR, PRM1, GBA2, PCI, CREM, TH2A, TH2B, ODF1, Cntrob, OAZ-t, HOOK1, SPEM1, GAT1, PRSS21, 15-LOX, Sptrx, AKAP3, AKAP4, DNAI1, DNAH5, RSPH4A, TXNDC3, CCDC39, LRRC6, LRRC50, KTU and so on.
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.
Impact
Slager et al., Bethesda, United States. In Nat Genet, 2013
We also found evidence for two additional promising loci below genome-wide significance at 8q22.3 (ODF1, P=5.40×10(-8)) and 5p15.33 (TERT, P=1.92×10(-7)).
Ectopic Expression of Cenexin1 S796A Mutant in ODF2(+/-) Knockout Background Causes a Sperm Tail Development Defect.
Lee, Bethesda, United States. In Dev Reprod, 2012
The outer dense fiber 2 (ODF2) protein is an important component of sperm tail outer dense fiber and localizes at the centrosome.
Specific expression of Kcna10, Pxn and Odf2 in the organ of Corti.
GeneRIF
Lewis et al., Cambridge, United Kingdom. In Gene Expr Patterns, 2012
In adult mice, Odf2 expression was marked in the interdental cells, Boettcher cells, the root cells and root cell processes. Fainter expression was also visible in the hair cells of the maculae and cristae
Coordinated ciliary beating requires Odf2-mediated polarization of basal bodies via basal feet.
Impact
GeneRIF
Tsukita et al., Ōsaka, Japan. In Cell, 2012
C-terminal region of Odf2 in mice is sufficient for ciliogenesis, the resulting basal bodies lack basal feet; loss of basal feet in ciliated epithelia disrupts polarized organization of apical microtubule lattice without affecting planar cell polarity.
Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.
GeneRIF
Inagaki et al., Nagoya, Japan. In J Cell Sci, 2011
Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.
Cdk5 in the centriolar appendages mediates cenexin1 localization and primary cilia formation.
GeneRIF
Lee et al., In Cell Cycle, 2010
Cdk5 in the centriolar appendages mediates cenexin1 localization and primary cilia formation.
Gene trap mutation of murine outer dense fiber protein-2 gene can result in sperm tail abnormalities in mice with high percentage chimaerism.
GeneRIF
van der Hoorn et al., Calgary, Canada. In Bmc Dev Biol, 2009
Results document the possible impact of loss of one Odf2 allele on sperm tail structure and function, resulting in a novel sperm tail phenotype.
A testis specific auto-antigen TSA70 belongs to Odf2/Cenexin family.
Review
Wakle et al., Mumbai, India. In Soc Reprod Fertil Suppl, 2006
Preliminary sequence analysis showed that TSA70 belongs to the Odf2/ Cenexin family.
Bypassing natural sperm selection during fertilization: the azh mutant offspring experience and the alternative of spermiogenesis in vitro.
Review
Tres et al., New York City, United States. In Mol Cell Endocrinol, 2002
For example, keratins Sak57, Odf1, and Odf2 are initially stored in the manchette before being sorted to the outer dense fibers and fibrous sheath of the developing spermatid tail.
Keratins: unraveling the coordinated construction of scaffolds in spermatogenic cells.
Review
Kierszenbaum, New York City, United States. In Mol Reprod Dev, 2002
The family of Odf proteins-Odf1, Odf2, and Odf3-includes an expanding group of proteins co-assembled along the axoneme during the development of the sperm tail.
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