The effect of statins on cancer cells--review.
Wrocław, Poland. In Tumour Biol, Jul 2015
Moreover, statins may change the arrangement of transporter OATP1, the localization of HMGCR, and could induce conformational changes in GLUT proteins.
Targeted drug delivery to treat pain and cerebral hypoxia.
Tucson, United States. In Pharmacol Rev, 2013
OATP/Oatp substrates include drugs that are efficacious in treatment of pain and/or cerebral hypoxia (i.e., opioid analgesic peptides, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors).