The effect of statins on cancer cells--review.
Wrocław, Poland. In Tumour Biol, Jul 2015
Moreover, statins may change the arrangement of transporter OATP1, the localization of HMGCR, and could induce conformational changes in GLUT proteins.
[Determinants of the stereoselective pharmacokinetics of fexofenadine].
Okinawa, Japan. In Yakugaku Zasshi, 2014
The findings suggested that a combination of multiple transporters involving organic anion transporting polypeptide (OATP) 2B1, P-glycoprotein (P-gp), and multidrug resistance-associated protein 2 (MRP2) react to stereoselective fexofenadine exposure.
Targeted drug delivery to treat pain and cerebral hypoxia.
Tucson, United States. In Pharmacol Rev, 2013
OATP/Oatp substrates include drugs that are efficacious in treatment of pain and/or cerebral hypoxia (i.e., opioid analgesic peptides, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors).