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Nucleoporin 54kDa

NUP54, nucleoporin p54
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Nucleoporin, POLYMERASE, p53, E-FABP, bcl-2
Papers on NUP54
Psoriatic T cells reduce epidermal turnover time and affect cell proliferation contributed from differential gene expression.
Zhang et al., Taiyuan, China. In J Dermatol, Sep 2015
Psoriatic T cells exhibited the ability to decrease epidermal turnover time and affect keratinocyte proliferation because of the differential expression of PPIL1, HSPH1, SENP3, NUP54, FABP5, PLEKHG3, SLC9A9 and CHCHD4.
Generation and comprehensive analysis of an influenza virus polymerase cellular interaction network.
Lotteau et al., Belgium. In J Virol, 2011
These are involved in cellular transcription (C14orf166, COPS5, MNAT1, NMI, and POLR2A), translation (EIF3S6IP), nuclear transport (NUP54), and DNA repair (FANCG).
LOH analysis of genes around D4S2964 identifies ARD1B as a prognostic predictor of hepatocellular carcinoma.
Wang et al., Guangzhou, China. In World J Gastroenterol, 2010
Larger tumor size was found to be significantly associated with LOH in genes ADP-ribosyltransferase 3 (ART3), nucleoporin 54 kDa (NUP54), scavenger receptor class B, member 2 (SCARB2) and coiled-coil domain containing 158 (CCDC158) (P = 0.043, P = 0.019, P = 0.001, P = 0.037, respectively).
Proteomic analysis of the effect of iptakalim on human pulmonary arterial smooth muscle cell proliferation.
Wang et al., Nanjing, China. In Acta Pharmacol Sin, 2009
We found that iptakalim could inhibit the proliferation of human PASMCs partly by affecting the expression of Hsp60, vimentin, nucleoporin P54 (NUP54) and Bcl-X(L) by opening the K(ATP) channel.
FISH-mapping comparison between river buffalo chromosome 7 and sheep chromosome 6: assignment of new loci and comparison with HSA4.
Iannuzzi et al., Napoli, Italy. In Cytogenet Genome Res, 2008
The following loci were mapped: GPR103 (BBU7q13, OAR6q13), TRAM1L1(OAR6q13dist), PPP3CA (BBU7q21, OAR6q15), SNCA (OAR6q17), PPARGC1A(BBU7q23, OAR6q17), UGDH (BBU7q25prox, OAR6q22prox), KDR (BBU7q27, OAR6q22), CNOT6L (BBU7q32prox, OAR6q32prox), NUP54 (BBU7q32, BBU6q32), DMP1 (BBU7q34dist-q36prox, OAR6q34dist-q36prox), QDPR (BBU7q36, OAR6q36).
Characterization of nuclear matrix protein alterations associated with renal cell carcinoma.
Getzenberg et al., Pittsburgh, United States. In Urology, 2007
Mass spectrometry peptide mass fingerprinting revealed that RCCA-1 appears to be a differentially spliced form of nucleoporin p54 that has been identified in endometrial carcinoma.
Macromolecular interactions in the nucleoporin p62 complex of rat nuclear pores: binding of nucleoporin p54 to the rod domain of p62.
Stewart et al., Cambridge, United Kingdom. In J Cell Biol, 1995
Nuclear pore complexes are constructed from a large number of different proteins, called collectively nucleoporins.
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