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Transcription factor 25

Nulp1, TCF25, Nuclear localized protein-1
TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in embryonic development (Steen and Lindholm, 2008 [PubMed 18068114]).[supplied by OMIM, Sep 2008] (from NCBI)
Top mentioned proteins: CAN, AGE, SET, DJ-1, NY-ESO-1
Papers on Nulp1
Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem.
Williams et al., London, United Kingdom. In Plos One, 2013
Hearing ability was strongly associated with DNA methylation levels in the promoter regions of several genes, including TCF25 (cg01161216, p = 6.6 × 10(-6)), FGFR1 (cg15791248, p = 5.7 × 10(-5) and POLE (cg18877514, p= 6.3 × 10(-5)).
Nuclear localized protein-1 (Nulp1) increases cell death of human osteosarcoma cells and binds the X-linked inhibitor of apoptosis protein.
Lindholm et al., Uppsala, Sweden. In Biochem Biophys Res Commun, 2008
These results indicate that Nulp1 plays a role in cell death control and may influence tumor growth.
Identification of prostate cancer antigens by automated high-throughput filter immunoscreening.
Gaudernack et al., Oslo, Norway. In J Immunol Methods, 2008
We then screened 18,000 cDNA clones from a phage display selected prostate tumour cDNA library with autologous patient antibodies and identified several relevant antigens such as NY-ESO-1, XAGE-1, DJ-1 and transcription factor 25 (TCF25).
hnulp1, a basic helix-loop-helix protein with a novel transcriptional repressive domain, inhibits transcriptional activity of serum response factor.
Wu et al., Changsha, China. In Biochem Biophys Res Commun, 2006
hnulp1 may act as a novel transcriptional repressor in serum response factor signaling pathways.
Crystallization and preliminary X-ray crystallographic analysis of a conserved domain in plants and prokaryotes from Pyrococcus horikoshii OT3.
Fukui et al., Suita, Japan. In Acta Crystallogr Sect F Struct Biol Cryst Commun, 2005
A plant- and prokaryote-conserved domain (PPC) has previously been found in AT-hook motif nuclear localized protein 1 (AHL1) localized in the nuclear matrix of Arabidopsis thaliana (AtAHL1).
Identification of a novel plant MAR DNA binding protein localized on chromosomal surfaces.
Fukui et al., Suita, Japan. In Plant Mol Biol, 2004
We identified a novel nucleoplasm localized protein in Arabidopsis called AT-hook motif nuclear localized protein 1 (AHL1), which was isolated by visual screening of transformants using random GFP::cDNA fusions.
Nulp1, a novel basic helix-loop-helix protein expressed broadly during early embryonic organogenesis and prominently in developing dorsal root ganglia.
Hjalt et al., Lund, Sweden. In Cell Tissue Res, 2002
The complex expression pattern and unique protein sequence, including an acidic amino terminal and putative transcription activation domain, suggests that Nulp1 may have a distinct role in embryonic development of many organs, including the adult brain.
The human melanocortin-1 receptor locus: analysis of transcription unit, locus polymorphism and haplotype evolution.
Sturm et al., Brisbane, Australia. In Gene, 2002
The complete sequence of the MC1R locus has been assembled, the coding region of the gene is intronless and placed within a 12 kb region flanked by the NULP1 and TUBB4 genes.
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