NAD captureSeq indicates NAD as a bacterial cap for a subset of regulatory RNAs.
Heidelberg, Germany. In Nature, Apr 2015
Analogous to a eukaryotic cap, 5'-NAD modification is shown in vitro to stabilize RNA against 5'-processing by the RNA-pyrophosphohydrolase RppH and against endonucleolytic cleavage by ribonuclease (RNase) E. The nudix phosphohydrolase NudC decaps NAD-RNA and thereby triggers RNase-E-mediated RNA decay, while being inactive against triphosphate-RNA.
Cytokinesis and cancer: Polo loves ROCK'n' Rho(A).
Beijing, China. In J Genet Genomics, 2010
We review current understandings of the interplay between Plk1, RhoA proteins and other proteins (e.g., NudC, MKLP2, PRC1, CEP55) involved in cytokinesis, with particular emphasis of its clinical implications in cancer.