gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 15 Apr 2015.


nucleolin, NCL, C23, Nucl, CLN5
Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, V1a, HAD, ACID, fibrillin-1
Papers using nucleolin antibodies
A phase I trial of adeno-associated virus serotype 1-γ-Sarcoglycan gene therapy for limb girdle muscular dystrophy type 2C
Danos Olivier et al., In Molecular Therapy. Nucleic Acids, 2011
... Dystrophin and α-actinin proteins were detected by probing the membrane with 1:100 dilution of NCL-DYS1 primary antibody (monoclonal antibody to dystrophin R8 repeat; NovoCastra) and 1:200 dilution of α-actinin primary antibody (Santa Cruz Biotechnology), respectively ...
Accurate quantification of dystrophin mRNA and exon skipping levels in duchenne muscular dystrophy
Aartsma-Rus Annemieke et al., In Molecular Therapy. Nucleic Acids, 2009
... dried milk (Campina Melkunie, Maasdam, the Netherlands) in TBS followed by an overnight incubation with NCL-DYS1 (dilution 1:125; Novacastra, Leica Microsystems, Valkerswaard, the Netherlands) ...
Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid
Brünner Nils et al., In Histopathology, 2008
... GmbH), and for ELISA and immunoblotting experiments the corresponding CB11 antibody concentrate was employed (Novocastra NCL-CB11; Leica Microsystems A/S, Ballerup, Denmark) ...
Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion
Arlt Alexander, In PLoS ONE, 2005
... Anti-luciferase antibody came from Promega, anti-nucleolin and anti-IκB antibody from Santa Cruz Biotechnology, anti-HIF-1α and anti-p21 antibody ...
Neurological disease in HIV-infected patients in the era of highly active antiretroviral treatment: a Brazilian experience
Adad Sheila Jorge et al., In AIDS Research and Treatment, 2005
... reaction (polymer technique) was made in some cases using monoclonal antibodies for toxoplasma (Novocastra-NCL-TG-TP3), cytomegalovirus (Novocastra-NCL-CMV-pp65), herpes virus (Dako HSV-I and II), JC ...
more suppliers
Papers on nucleolin
Chimeric nucleolin aptamer with survivin DNAzyme for cancer cell targeted delivery.
Krishnakumar et al., Chennai, India. In Chem Commun (camb), 25 May 2015
A chimeric aptamer-DNAzyme conjugate was generated for the first time using a nucleolin aptamer (NCL-APT) and survivin Dz (Sur_Dz) and exhibited the targeted killing of cancer cells.
Identification of 8 Novel Capsular Polysaccharide Synthesis Gene Loci in Non-typable Streptococcus suis.
Xu et al., Changping, China. In Appl Environ Microbiol, 10 May 2015
Eight novel cps loci (NCL) were found, all of which were located between the orfZ-orfX region and glf gene.
Study of the Function of G-rich aptamers selected for lung adenocarcinoma.
Ye et al., Gainesville, United States. In Chem Asian J, 10 May 2015
Their binding, internalization and antiproliferation activity in cancer and noncancer cells were investigated by flow cytometry and MTS assay, and compared with those of nucleolin-binding AS1411 and thrombin-binding aptamer.
The roles of nucleolin subcellular localization in cancer.
Bouvet et al., Lyon, France. In Biochimie, 09 May 2015
UNASSIGNED: Nucleolin (NCL) is one of the most abundant non ribosomal protein of the nucleolus where it plays a central role in polymerase I transcription.
Proteomic Analysis of the Palmitoyl Protein Thioesterase 1 Interactome in SH-SY5Y Human Neuroblastoma Cells.
Lalowski et al., Helsinki, Finland. In J Proteomics, 09 May 2015
UNASSIGNED: Neuronal ceroid lipofuscinoses (NCL) are a group of inherited progressive childhood disorders, characterized by early accumulation of autofluorescent storage material in lysosomes of neurons or other cells.
Nucleolin: dual roles in rDNA chromatin transcription.
Sáez-Vásquez et al., Perpignan, France. In Gene, Mar 2015
Nucleolin is a major nucleolar protein conserved in all eukaryotic organisms.
Simultaneous Imaging of Two Different Cancer Biomarkers Using Aptamer-Conjugated Quantum Dots.
Kim et al., Kangnŭng, South Korea. In Sensors (basel), Dec 2014
In this study, simultaneous imaging of the cancer biomarkers, tenascin-C and nucleolin, was performed using two types of aptamer-conjugated QDs.
Respiratory syncytial virus receptor expression in the mouse and viral tropism.
Hegele et al., Toronto, Canada. In Histol Histopathol, Dec 2014
With the discovery of cell-surface nucleolin as a fusion receptor for RSV, the question arose as to whether nucleolin could explain RSV tropism in vivo.
From protein total synthesis to peptide transamidation and metathesis: playing with the reversibility of N,S-acyl or N,Se-acyl migration reactions.
Agouridas et al., Lille, France. In Curr Opin Chem Biol, Oct 2014
One amide-forming reaction is native chemical ligation (NCL) which is driven by a sulfur to nitrogen acyl migration process from a transient thioester intermediate.
C9orf72 nucleotide repeat structures initiate molecular cascades of disease.
Wang et al., Baltimore, United States. In Nature, Apr 2014
Specifically, nucleolin, an essential nucleolar protein, preferentially binds the HRE G-quadruplex, and patient cells show evidence of nucleolar stress.
DNA and RNA quadruplex-binding proteins.
Fojta et al., Brno, Czech Republic. In Int J Mol Sci, 2013
The NHE III1 region of the c-MYC promoter has been shown to interact with nucleolin protein as well as other G-quadruplex-binding proteins.
Heat shock cognate 70 regulates the translocation and angiogenic function of nucleolin.
Luo et al., Beijing, China. In Arterioscler Thromb Vasc Biol, 2012
Hsc70 is a prerequisite for the surface translocation and angiogenic function of nucleolin, which suggests strategies to target both Hsc70 and NCL for more effective antiangiogenic therapies.
The maize b1 paramutation control region causes epigenetic silencing in Drosophila melanogaster.
Lloyd et al., Halifax, Canada. In Mol Genet Genomics, 2012
Data show that maize B1 transgenic lines exhibit cis-silencing of white gene but epigenetic activation of white gene expression in trans.
H3S10 phosphorylation by the JIL-1 kinase regulates H3K9 dimethylation and gene expression at the white locus in Drosophila.
Johansen et al., Ames, United States. In Fly (austin), 2012
H3K9me2 levels at the white gene directly correlate with its level of expression.
Nucleolin inhibits G4 oligonucleotide unwinding by Werner helicase.
Bohr et al., Baltimore, United States. In Plos One, 2011
WRNp interacts with the RNA-binding protein, NCL.
Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor β transcription in breast cancer cells.
Klinge et al., Louisville, United States. In Plos One, 2011
nucleolin plays a coregulatory role in transcriptional regulation of the tumor suppressor RARB2 by COUP-TFII
Chemoselectivity in chemical biology: acyl transfer reactions with sulfur and selenium.
Raines et al., Madison, United States. In Acc Chem Res, 2011
One focus of our research is furthering the chemistry of native chemical ligation (NCL) and expressed protein ligation (EPL), two related processes that enable the synthesis and semisynthesis of proteins.
Identification of nucleolin as a cellular receptor for human respiratory syncytial virus.
Hegele et al., Vancouver, Canada. In Nat Med, 2011
Nucleolin is a cellular receptor for human respiratory syncytial virus.
Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage.
Knoblich et al., Vienna, Austria. In Nature, 2008
Whereas neuroblasts segregate the Trim-NHL (tripartite motif and Ncl-1, HT2A and Lin-41 domain)-containing protein Brain tumour (Brat) into one of the two daughter cells, ovarian stem cells are regulated by an extracellular signal from the surrounding stem cell niche.
Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin.
Kastan et al., Memphis, United States. In Cell, 2005
These findings demonstrate the importance of increased translation of p53 in DNA-damage responses and suggest critical roles for RPL26 and nucleolin in affecting p53 induction.
More papers using nucleolin antibodies
Hsp90 restrains ErbB-2/HER2 signalling by limiting heterodimer formation.
Koch Karl-Wilhelm, In PLoS ONE, 2003
... ErbB1, ErbB2, ErbB3, ErbB4 antibodies, monoclonal mouse anti-phosphotyrosine (PY20), mouse anti-GFP (B-2) and mouse anti-nucleolin (C23) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA) ...
Identification of heparin affin regulatory peptide domains with potential role on angiogenesis
Delbé Jean et al., In BMC Cancer, 2003
... Monoclonal antibody to human nucleolin was from Santa Cruz biotechnology (Montrouge, France), goat anti-mouse ...
Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.
Nurminsky Dmitry I., In PLoS ONE, 2002
... P-PKC-zeta (Abcam, ab76129), Syntaxin 4 (Abcam, ab57841), Vamp2 (Abcam, ab3347), Vimentin (Santacruz, sc73259, Actin (Santacruz, sc-1615), Nucleolin (Santacruz, sc13057), Lamin A (Santacruz, sc-20680), MEF2C (Abcam, ab65252), HDAC4 (Cell Signaling, ...
The biological action of saponins in animal systems: a review.
Means Robert E., In PLoS ONE, 2001
... Antibodies against ERK, JNK, Akt, NF-κB (p65), C23 and phosphorylated proteins were purchased from Santa Cruz Biotechnology (Santa Cruz, CA) ...
WRN helicase accelerates the transcription of ribosomal RNA as a component of an RNA polymerase I-associated complex.
Borgmann Kerstin, In PLoS ONE, 2001
... Marek Rusin, Maria Sklodowska-Curie Memorial Institute, Gliwice, Poland; GFP-NCL constructs are described below.The following antibodies were purchased from Santa Cruz Biotechnology (Santa Cruz, CA): Rabbit ...
Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest
Harris Curtis C. et al., In The Journal of Cell Biology, 2001
... Anti-Nucleolin (C23): monoclonal MS-3 (Santa Cruz Biotechnology, Inc.) ...
Making ribosomes.
Takahashi Nobuhiro et al., In Molecular & Cellular Proteomics : MCP, 1999
... Antibodies against B23, fibrillarin, and nucleolin were obtained from Santa Cruz Biotechnology (Santa Cruz, CA).
Transduction by adeno-associated virus vectors in the rabbit airway: efficiency, persistence, and readministration
Gabellini Davide et al., In Molecular Therapy, 1996
... serum, the sections were incubated O/N with a mix of two anti-mouse Dystrophin antibodies (NCL-Dys1 and NCL-Dys2; Novacastra, Leica Microsystem, Wetzlar, Germany) diluted ...
Temperature-dependent physiological stability of rat skeletal muscle in vitro.
Vina Jose, In PLoS ONE, 1984
... Dystrophin antibody (NCL-DYS2) was from Novocastra Vector Laboratories (Burlingame, CA) ...
share on facebooktweetadd +1mail to friends