Nuclear Respiratory Factor 1
[Differential gene expression profiling for identification of protective transcription factors in different subtypes of nasopharyngeal carcinoma.]
Guangzhou, China. In Nan Fang Yi Ke Da Xue Xue Bao, 20 Dec 2013
RESULTS: In NPC_I samples, 80 transcription factors were found to be up-regulated, in which RUNX3, GATA3, NR3C1, NRF1, RXRA, SMAD7, TBP, and ZBTB6 were positive factors and HLF and MTF1 were negative factors, involved in the regulation of the genes in T cell receptor signaling pathway.
PPARgamma agonist pioglitazone does not enhance performance in mice.
Valencia, Spain. In Drug Test Anal, 20 Dec 2013
We found that the peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) and the nuclear respiratory factor-1 (NRF-1) protein content and citrate synthase activity significantly increased in the soleus muscle of trained animals.
Thioredoxin-mediated redox regulation of resistance to endocrine therapy in breast cancer.
Miami, United States. In Biochim Biophys Acta, Aug 2013
This, in turn, may lead to the disruption of reversible redox signaling that involves redox-sensitive phosphatases, protein kinases, such as, ERK and AKT, and transcription factors, such as, AP-1, NRF-1 and NF-κB.
Role of PGC-1α signaling in skeletal muscle health and disease.
Minneapolis, United States. In Ann N Y Acad Sci, Oct 2012
PGC-1α is the master transcription regulator that stimulates mitochondrial biogenesis, by upregulating nuclear respiratory factors (NRF-1, 2) and mitochondrial transcription factor A (Tfam), which leads to increased mitochondrial DNA replication and gene transcription.