Nuclear Respiratory Factor 1
Dihydromyricetin Improves Physical Performance Under Simulated High Altitude.
Chongqing, China. In Med Sci Sports Exerc, Apr 2014
Protein expression of mitochondrial biogenesis markers including peroxisome proliferator-activated receptor-γ coactivator 1α, sirtuin1, nuclear respiratory factor 1, mitochondrial transcription factor A, AMP-activated protein kinase, and AMPK phosphorylation, were significantly down-regulated in HH, while DHM pretreatment significantly restored expression levels.
Thioredoxin-mediated redox regulation of resistance to endocrine therapy in breast cancer.
Miami, United States. In Biochim Biophys Acta, Aug 2013
This, in turn, may lead to the disruption of reversible redox signaling that involves redox-sensitive phosphatases, protein kinases, such as, ERK and AKT, and transcription factors, such as, AP-1, NRF-1 and NF-κB.
Role of PGC-1α signaling in skeletal muscle health and disease.
Minneapolis, United States. In Ann N Y Acad Sci, 2012
PGC-1α is the master transcription regulator that stimulates mitochondrial biogenesis, by upregulating nuclear respiratory factors (NRF-1, 2) and mitochondrial transcription factor A (Tfam), which leads to increased mitochondrial DNA replication and gene transcription.