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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Nucleobindin 1

Nuc, CALNUC, Nucleobindin, NUCB1, nucleobindin 1
This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events. [provided by RefSeq, Jun 2010] (from NCBI)
Top mentioned proteins: ACID, CAN, HAD, POLYMERASE, Insulin
Papers using Nuc antibodies
Effect of ACAT inhibition on the progression of coronary atherosclerosis
Supplier
Achermann John C. et al., In The Journal of Clinical Endocrinology and Metabolism, 2005
... overexpression was performed using the full-length coding sequence of wild-type (WT) human SF-1 cloned into a pIRES2-AcGFP1-Nuc vector (Clontech-Takara Bio Europe, Saint-Germain-en-Laye, France) ...
Contrasting nuclear dynamics of the caspase-activated DNase (CAD) in dividing and apoptotic cells
Supplier
Lukacs Gergely L. et al., In The Journal of Cell Biology, 2000
... Nuclear-targeted EGFP (GFP-NLS) was derived from pECFP-NUC (BD Biosciences).
Inhibition of Wnt activity induces heart formation from posterior mesoderm.
Supplier
Callaerts Patrick, In PLoS ONE, 2000
... Anderson, and pDsRed-Nuc vector was purchased from Clontech).
Induction of transient macroapertures in endothelial cells through RhoA inhibition by Staphylococcus aureus factors
Supplier
Lemichez Emmanuel et al., In The Journal of Cell Biology, 2000
... Other DNA constructs used were pDsRed2-Nuc (CLONTECH Laboratories, Inc.), canis Caveolin1 ...
Papers on Nuc
Nucleobindin 1 (NUCB1) is a Golgi-resident marker of neurons.
New
Broberger et al., Stockholm, Sweden. In Neuroscience, Mar 2016
Nucleobindin 1 (NUCB1; also known as CALNUC or NUC) is a putative DNA- and calcium-binding protein and exhibits significant structural homology with the protein nucleobindin 2 (NUCB2; also known as nesfatin).
Clinical implication of serum WFA+ -M2BP level on Hepatitis B e Antigen loss or Seroconversion in Hepatitis B e Antigen-positive patients.
New
Nishiguchi et al., Japan. In Hepatol Res, Feb 2016
BACKGROUND AND AIMS: To examine the impact of pretreatment Wisteria floribunda agglutinin-positive Mac-2-binding protein (WFA(+) -M2BP) level on hepatitis B e antigen (HBeAg) loss or HBeAg seroconversion (SC) for patients with nucleoside analogue (NUC) therapy naïve HBeAg-positive chronic hepatitis B (CHB).
Calnuc function in endosomal sorting of lysosomal receptors.
New
Lavoie et al., Sherbrooke, Canada. In Traffic, Feb 2016
UNASSIGNED: Calnuc is a ubiquitous Ca(2+) -binding protein present on the trans-Golgi network (TGN) and endosomes.
Association of the Polymorphism in Nucleobindin 2 Gene and the Risk of Metabolic Syndrome.
New
Wan et al., Qingdao, China. In Genet Test Mol Biomarkers, Jan 2016
OBJECTIVE: Nesfatin-1, originates from the precursor protein nucleobindin 2 (NUCB2) and plays an important role in the development of metabolic syndrome (MetS), including obesity and hypertension.
Natural killer cell phenotype modulation and natural killer/T-cell interplay in nucleos(t)ide analogue-treated hepatitis e antigen-negative patients with chronic hepatitis B.
New
Ferrari et al., Parma, Italy. In Hepatology, Dec 2015
Understanding to what extent nucleos(t)ide analogue (NUC) therapy can improve T- and NK-cell responses is important in the perspective of immunomonitoring strategies for a safe and earlier NUC withdrawal and of novel combination therapies based on modulation of antiviral immunity.
HDAC5-mTORC1 Interaction in Differential Regulation of Ghrelin and Nucleobindin 2 (NUCB2)/Nesfatin-1.
New
Zhang et al., Beijing, China. In Mol Endocrinol, Nov 2015
Alterations in ghrelin and nucleobindin 2/nesfatin-1 were mediated by HDAC5 but not HDAC4.
Loss of DNase II function in the gonad is associated with a higher expression of antimicrobial genes in Caenorhabditis elegans.
New
Lo et al., Tainan City, Taiwan. In Biochem J, Sep 2015
Although the exact roles of the three DNase II genes (nuc-1, crn-6 and crn-7), which are known to mediate degradation of apoptotic DNA, in the embryonic and larval phases of apoptosis have been characterized, the DNase II acting in the third wave of germ cell apoptosis remains undetermined.
A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells.
New
Impact
Cravatt et al., Los Angeles, United States. In Cell, Jul 2015
In further support of this finding, we describe a selective ligand for the lipid-binding protein nucleobindin-1 (NUCB1) and show that this compound perturbs the hydrolytic and oxidative metabolism of endocannabinoids in cells.
Nesfatin-1 and the Cardiovascular System: Central and Pheripheral Actions and Cardioprotection.
Review
Cerra et al., Rende, Italy. In Curr Drug Targets, 2014
In mammalian hypothalamus, Nesfatin-1 is expressed, together with the precursor Nucleobindin 2 (NUCB2), in regions controlling water-food intake, body weight, and glucose homeostasis.
VdNUC-2, the Key Regulator of Phosphate Responsive Signaling Pathway, Is Required for Verticillium dahliae Infection.
Lin et al., Nanjing, China. In Plos One, 2014
NUC-2/PHO81 and its homologs are one of the most important components in the regulation pathway.
Directly acting antivirals (DAAs) for the treatment of chronic hepatitis C virus infection in liver transplant patients: "a flood of opportunity".
Review
Agarwal et al., Auckland, New Zealand. In Am J Transplant, 2014
Fortunately, other classes of DAAs targeting different steps of HCV replication are in clinical trials, including nucleotide polymerase (NUC-NS5B) inhibitors, nonnucleotide polymerase (non-NUC-NS5B) inhibitors and NS5A inhibitors.
Hepatitis B and C in liver transplantation: new strategies to combat the enemies.
Review
Cicinnati et al., Münster, Germany. In Rev Med Virol, 2013
Hepatitis B immune globulin-free therapeutic regimens with a nucleos(t)ide analogue (NUC) or NUC combinations after liver transplantation (LT) are currently being investigated for their efficacy and safety as HBV re-infection prophylaxis in clinical studies.
Nucleobindin 1 caps human islet amyloid polypeptide protofibrils to prevent amyloid fibril formation.
GeneRIF
Sakmar et al., New York City, United States. In J Mol Biol, 2012
postulate that the engineered forms of NUCB1 prevent hIAPP fibril formation by a mechanism where protofibril-like species are "capped" to prevent further fibril assembly and maturation
Nucleobindins: bioactive precursor proteins encoding putative endocrine factors?
Review
Unniappan et al., Toronto, Canada. In Gen Comp Endocrinol, 2012
The nucleobindins, nucleobindin 1 (NUCB1) and nucleobindin 2 (NUCB2), are homologous multidomain calcium and DNA binding proteins.
G Protein binding sites on Calnuc (nucleobindin 1) and NUCB2 (nucleobindin 2) define a new class of G(alpha)i-regulatory motifs.
GeneRIF
Farquhar et al., San Diego, United States. In J Biol Chem, 2011
structural basis for the properties of Calnuc and NUCB2 binding to Galpha subunits and its regulation by calcium ions.
Epigenetic regulation of HIV-1 transcription.
Review
Herbein et al., Besançon, France. In Epigenomics, 2011
Nuc-1, a nucleosome located immediately downstream of the HIV-1 transcriptional initiation site directly impedes long-terminal repeat (LTR) activity.
Nucleobindin 1 is a calcium-regulated guanine nucleotide dissociation inhibitor of G{alpha}i1.
GeneRIF
Sakmar et al., New York City, United States. In J Biol Chem, 2010
Nucleobindin 1 is a calcium-regulated guanine nucleotide dissociation inhibitor of G{alpha}i1.
A novel endoplasmic reticulum export signal: proline at the +2-position from the signal peptide cleavage site.
GeneRIF
Tomida et al., Tokyo, Japan. In J Biol Chem, 2009
Proline residue at the +2-position (Pro(+2)) from the signal peptide cleavage site is the determinant of NUCB1 protein export from the ER and subsequent transport to the Golgi.
Modulation of nucleobindin-1 and nucleobindin-2 by caspases.
GeneRIF
Liu et al., Chapel Hill, United States. In Febs Lett, 2008
results suggest that the functions of nucleobindins could be modulated by caspase-mediated cleavage in apoptosis
Complete nucleotide sequence of SV40 DNA.
Impact
Ysebaert et al., In Nature, 1978
Codons of the type NUC, NCG and CGN are absent or very rare.
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