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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Polycomb group ring finger 1

NSPc1, Nervous system polycomb 1
PCGF1 is a mammalian homolog of the Drosophila polycomb group genes, which act as transcriptional repressors to regulate anterior-posterior patterning in early embryonic development (Nunes et al., 2001 [PubMed 11287196]). See also PCGF2 (MIM 600346).[supplied by OMIM, Aug 2008] (from NCBI)
Papers on NSPc1
Polycomb group ring finger 1 cooperates with Runx1 in regulating differentiation and self-renewal of hematopoietic cells.
Buchholz et al., Dresden, Germany. In Blood, 2012
Pcgf1 is an epigenetic regulator of hematopoietic cell differentiation. Simultaneous depletion of Runx1 and Pcgf1 allows sustained self-renewal while blocking differentiation of lineage marker-negative cells in vitro.
[Expression pattern of polycomb gene Nspc1 at the early developmental stage in zebrafish].
Peng et al., Beijing, China. In Zhongguo Yi Xue Ke Xue Yuan Xue Bao, 2008
Nspc1 was expressed globally at the early stage.
Stem cells and cancer; the polycomb connection.
van Lohuizen et al., Amsterdam, Netherlands. In Cell, 2004
polycomb has a role in stem cell fate and development of cancer (review)
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