CNVs in neuropsychiatric disorders.
Cardiff, United Kingdom. In Hum Mol Genet, Nov 2015
Over the last few years at least 11 copy number variations (CNVs) have been shown convincingly to increase risk to developing schizophrenia: deletions at 1q21.1, NRXN1, 3q29, 15q11.2,
Recent genomic advances in schizophrenia.
Cardiff, United Kingdom. In Clin Genet, 2012
There is evidence both for an increased burden of large, rare CNVs in schizophrenia and that risk is conferred by a number of specific large CNVs as well as by deletions of NRXN1 which encodes the synaptic scaffolding protein neurexin 1.