Modulation in Natriuretic Peptides System in Experimental Colitis in Rats.
Chŏnju, South Korea. In Dig Dis Sci, Jan 2016
The colonic natriuretic peptide receptor-A mRNA level and particulate guanylyl cyclase activity in response to ANP from colonic tissue membranes were higher, and the mRNA levels of ANP and natriuretic peptide receptor-B were lower in DSS-treated rats than in control rats.
C-type natriuretic peptide: a new cardiac mediator.
Pisa, Italy. In Peptides, 2013
Taken together, these observations suggest that CNP and its specific receptor, NPR-B, can play a very important role in regulating cardiac hypertrophy and remodeling, indicating NPR-B as a new potential drug target for the treatment of cardiovascular disease.