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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Ribosomal protein L10

NOV, CCN3, plexin-A1, novH
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L10E family of ribosomal proteins. It is located in the cytoplasm. In vitro studies have shown that the chicken protein can bind to c-Jun and can repress c-Jun-mediated transcriptional activation, but these activities have not been demonstrated in vivo. This gene was initially identified as a candidate for a Wilms tumor suppressor gene, but later studies determined that this gene is not involved in the suppression of Wilms tumor. This gene has been referred to as 'laminin receptor homolog' because a chimeric transcript consisting of sequence from this gene and sequence from the laminin receptor gene was isolated; however, it is not believed that this gene encodes a laminin receptor. Alternative splicing results in multiple transcript variants. This gene also uses multiple polyA signals, with the 3'-most polyA signal overlapping the deoxyribonuclease I-like 1 gene on the opposite strand. This gene is co-transcribed with the small nucleolar RNA gene U70, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Feb 2012] (from NCBI)
Top mentioned proteins: connective tissue growth factor, Cyr61, CAN, POLYMERASE, Gi
Papers on NOV
Optimization of Norovirus Virus-Like Particle Production in Pichia Pastoris Using a Real-Time Near-Infrared Bioprocess Monitor.
Batt et al., Ithaca, United States. In Biotechnol Prog, Feb 2016
UNASSIGNED: The production of norovirus virus-like particles (NoV VLPs) displaying NY-ESO-1 cancer testis antigen in Pichia pastoris BG11 Mut(S) has been enhanced through feed-strategy optimization using a near-infrared bioprocess monitor (RTBio® Bioprocess Monitor, ASL Analytical, Inc.), capable of monitoring and controlling the concentrations of glycerol and methanol in real-time.
CCN1 (CYR61) and CCN3 (NOV) signaling drives human trophoblast cells into senescence and stimulates migration properties.
Gellhaus et al., Essen, Germany. In Cell Adh Migr, Feb 2016
This study focused on the regulation properties of glycosylated and non-glycosylated matricellular CCN1 and CCN3, primarily for proliferation control in the benign SGHPL-5 trophoblast cell line, which originates from the first-trimester placenta.
A trivalent vaccine candidate against hepatitis E virus, norovirus, and astrovirus.
Tan et al., Cincinnati, United States. In Vaccine, Feb 2016
UNASSIGNED: Hepatitis E virus (HEV), norovirus (NoV), and astrovirus (AstV) are enterically-transmitted viral pathogens causing epidemic or endemic hepatitis (HEV) and gastroenteritis (NoV and AstV) respectively in humans, leading to significant morbidity and mortality worldwide.
Establishment of a novel method without sequence modification for developing NoV P particle-based chimeric vaccines.
Kong et al., Changchun, China. In Protein Expr Purif, Feb 2016
UNASSIGNED: The Norovirus (NoV) P particle (PP) is a subviral particle formed by 24 copies of the protruding (P) domain of the capsid protein.
A novel feline norovirus in diarrheic cats.
Martella et al., Teramo, Italy. In Infect Genet Evol, Jan 2016
The sequence of ~3.4-kb portion at the 3' end of the genome of a NoV strain, TE/77-13/ITA, was determined.
[Research Progress in Norovirus Bioaccumulation in Shellfish].
Ma et al., In Bing Du Xue Bao, May 2015
While HBGAs might be the main reason that NoVs are accumulated in shellfish, the detailed mechanism behind NoV concentration and bioaccumulation in shellfish is not clear.
Commensal microbes and interferon-λ determine persistence of enteric murine norovirus infection.
Virgin et al., Saint Louis, United States. In Science, Feb 2015
The capacity of human norovirus (NoV), which causes >90% of global epidemic nonbacterial gastroenteritis, to infect a subset of people persistently may contribute to its spread.
Eyeing the Cyr61/CTGF/NOV (CCN) group of genes in development and diseases: highlights of their structural likenesses and functional dissimilarities.
Chaqour et al., United States. In Hum Genomics, 2014
"CCN" is an acronym referring to the first letter of each of the first three members of this original group of mammalian functionally and phylogenetically distinct extracellular matrix (ECM) proteins [i.e., cysteine-rich 61 (CYR61), connective tissue growth factor (CTGF), and nephroblastoma-overexpressed (NOV)].
Matricellular proteins of the Cyr61/CTGF/NOV (CCN) family and the nervous system.
Jaworski et al., Warsaw, Poland. In Front Cell Neurosci, 2014
Among matricellular proteins are members of the Cyr61/CTGF/NOV (CCN) protein family.
Role of histo-blood group antigens in primate enteric calicivirus infections.
Sestak, United States. In World J Virol, 2014
Human noroviruses (NoV) are associated with large proportion of non-bacterial diarrhea outbreaks together with > 50% of food-associated diarrheas.
Input of microenvironmental regulation on colorectal cancer: role of the CCN family.
Kuo et al., Taipei, Taiwan. In World J Gastroenterol, 2014
Many studies have shown that CCN members, such as CCN1, CCN2, CCN3, Wnt-induced secreted protein (WISP)-1, WISP-2, and WISP-3, are dysregulated in CRC, which implies potential diagnostic markers or therapeutic targets clinically.
RNA interference functions as an antiviral immunity mechanism in mammals.
Ding et al., Riverside, United States. In Science, 2013
Here, we show that infection of hamster cells and suckling mice by Nodamura virus (NoV), a mosquito-transmissible RNA virus, requires RNAi suppression by its B2 protein.
Agonist-independent GPCR activity regulates anterior-posterior targeting of olfactory sensory neurons.
Sakano et al., Tokyo, Japan. In Cell, 2013
We found that mutants with altered agonist-independent activity changed the transcription levels of axon-targeting molecules--e.g., Neuropilin-1 and Plexin-A1--but not of glomerular segregation molecules--e.g., Kirrel2 and Kirrel3--thus causing shifts in glomerular locations along the anterior-posterior (A-P) axis.
Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.
Eichmann et al., Paris, France. In Circ Res, 2012
Data demonstrate an essential direct function of Sema3A-Nrp1-PlexinA1 signaling in lymphatic valve formation.
Study of CCN3 (NOV) and DDR1 in normal melanocytes and vitiligo skin.
Cario-André et al., Bordeaux, France. In Exp Dermatol, 2012
Melanocytes remaining in perilesional vitiligo skin did not express CCN3.
Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.
Mason et al., New York City, United States. In Neuron, 2012
These findings suggest a mechanism by which a complex of Sema6D, Nr-CAM, and Plexin-A1 at the chiasm midline alters the sign of Sema6D and signals Nr-CAM/Plexin-A1 receptors on retinal ganglion cells to implement the contralateral retinal cell projection.
A novel, dual role of CCN3 in experimental glomerulonephritis: pro-angiogenic and antimesangioproliferative effects.
Floege et al., Aachen, Germany. In Am J Pathol, 2012
A novel, dual role of CCN3 in experimental glomerulonephritis: pro-angiogenic and antimesangioproliferative effects.
CCN3 increases cell motility and ICAM-1 expression in prostate cancer cells.
Tang et al., T'ai-chung-shih, Taiwan. In Carcinogenesis, 2012
results indicate that CCN3 enhances the migration of prostate cancer cells by increasing ICAM-1 expression through a signal transduction pathway that involves alphavbeta3 integrin, ILK, Akt and NF-kappaB
Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II.
Kumanogoh et al., Suita, Japan. In Nat Immunol, 2010
involved in the entry of dendritic cells into the lymphatics as a principal receptor for semaphorins
NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells.
Enver et al., Radcliffe, United Kingdom. In Science, 2007
Nov is identified as being essential for the functional integrity of hematopoietic stem and progenitor cells
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