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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Non-POU domain containing, octamer-binding

non-O, p54nrb, p54(nrb)
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq, Feb 2009] (from NCBI)
Top mentioned proteins: HAD, AGE, CAN, ACID, fibrillin-1
Papers using non-O antibodies
Mitochondrial Arginase II Modulates Nitric-Oxide Synthesis through Nonfreely Exchangeable l-Arginine Pools in Human Endothelial Cells.
Supplier
Bauer Joseph Alan, In PLoS ONE, 2005
... -nitro-L-arginine methyl ester) and DEA NONO-ate (Diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate) were purchased from Cayman Chemical Company (Ann Arbor, ...
Papers on non-O
Perioperative treatment of hemophilia A patients: Blood group O patients are at risk of bleeding complications.
New
Cnossen et al., Groningen, Netherlands. In J Thromb Haemost, Jan 2016
Blood group O patients had more bleeding complications in comparison to patients with blood group non-O (OR=2.02
Prognostic value of ABO blood group in patients with early stage cervical cancer treated with radical hysterectomy with pelvic node dissection.
New
Atjimakul et al., Thailand. In Tumour Biol, Jan 2016
Patients were stratified for analysis as either blood group O or non-O.
Giant poly(A)-rich RNP aggregates form at terminal regions of avian lampbrush chromosomes.
New
Gaginskaya et al., Saint Petersburg, Russia. In Chromosoma, Jan 2016
A subtype of GITERA concentrates hnRNP I/PTB and p54nrb/NonO.
Meta-Analysis of Non-O Blood Group as an Independent Risk Factor for Coronary Artery Disease.
Review
New
All-Literature Investigation of Cardiovascular Evidence (ALICE) Group et al., Shizuoka, Japan. In Am J Cardiol, Oct 2015
To determine whether non-O blood group is an independent risk factor for coronary artery disease (CAD), we performed a meta-analysis of contemporary studies reporting adjusted relative risk estimates using multivariable logistic regression and multivariable Cox proportional hazards regression.
[Association between ABO blood groups and coronary heart disease in Chinese Guangxi Zhuang population].
New
Liu et al., Nanning, China. In Zhonghua Xin Xue Guan Bing Za Zhi, Sep 2015
In addition, there were significant differences of Gensini score between non-O subjects and group O subjects in the CHD group, and MACE at 1-year follow-up was similar between ABO blood groups of CHD individuals.
PSF: nuclear busy-body or nuclear facilitator?
Review
New
Lynch et al., Philadelphia, United States. In Wiley Interdiscip Rev Rna, Jul 2015
Although grouped in a family with the proteins p54nrb/NONO and PSPC1 based on sequence homology, PSF contains additional protein sequence not included in other family members.
Possible mechanisms for intravenous immunoglobulin-associated hemolysis: clues obtained from review of clinical case reports.
Review
New
Padmore, Ottawa, Canada. In Transfusion, Jul 2015
These features included non-O blood group patients and treatment with high-dose IVIG as an immune-modulating agent for an underlying inflammatory or immune-mediated disorder.
Diabetes mellitus: Possible risk and promoting factors of cholangiocarcinoma: Association of diabetes mellitus and cholangiocarcinoma.
Review
New
Wongkham et al., Khon Kaen, Thailand. In Cancer Epidemiol, Jun 2015
The global epidemiological studies of risk factors for CCA in non-O.
Dosimetric impact of orthopedic metal artifact reduction (O-MAR) on Spine SBRT patients.
Djemil et al., Cleveland, United States. In J Appl Clin Med Phys, 2014
A clinical patient plan was applied to the artifact-free reference, non-O-MAR, and O-MAR phantom images with the titanium located either inside or outside of the tumor.
The relevance of coagulation in cardiovascular disease: what do the biomarkers tell us?
Review
Rumley et al., Glasgow, United Kingdom. In Thromb Haemost, 2014
The common haemostatic gene polymorphisms for factor II, factor V and the von Willebrand factor: Factor VIII (non-O blood group) show significant associations with coronary heart disease (CHD) risk, consistent with potential causality.
Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers.
Impact
Teh et al., Singapore, Singapore. In Nat Genet, 2013
To address this issue, we profiled 209 cholangiocarcinomas (CCAs) from Asia and Europe, including 108 cases caused by infection with the liver fluke Opisthorchis viverrini and 101 cases caused by non-O.
Proteomic identification of PSF and p54(nrb) as TopBP1-interacting proteins.
GeneRIF
Hänel et al., Jena, Germany. In J Cell Biochem, 2012
Localisation of TopBP1 at DNA damage sites was noticed as early as 5 s following damage induction, whereas p54(nrb) and PSF localised there after 20 s.
Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation.
GeneRIF
Bond et al., Australia. In Proc Natl Acad Sci U S A, 2012
The crystal structure of the heterodimer of the multidomain conserved region of the Drosophila behavior/human splicing proteins, PSPC1 and NONO, is described.
Crystallization of a paraspeckle protein PSPC1-NONO heterodimer.
GeneRIF
Bond et al., Australia. In Acta Crystallogr Sect F Struct Biol Cryst Commun, 2011
crystal of PSPC1-NONO contained one heterodimer in the asymmetric unit and diffracted to 1.9 A resolution using synchrotron radiation
The mitotic phosphorylation of p54(nrb) modulates its RNA binding activity.
GeneRIF
Vincent et al., Québec, Canada. In Biochem Cell Biol, 2011
p54(nrb) interaction with RNA could be selectively modulated by phosphorylation during mitosis
Rasd1 modulates the coactivator function of NonO in the cyclic AMP pathway.
GeneRIF
Chen et al., Singapore, Singapore. In Plos One, 2010
Study showed that Rasd1 and NonO interact at the CRE-site of specific target genes.
Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partners.
Impact
Guan et al., Ithaca, United States. In Nat Cell Biol, 2006
Here, we report the identification of nuclear N-WASP within a large nuclear-protein complex containing PSF-NonO (polypyrimidine-tract-binding-protein-associated splicing factor-non-Pou-domain octamer-binding protein/p54(nrb)), nuclear actin and RNA polymerase II.
PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator.
Impact
GeneRIF
Schibler et al., Genève, Switzerland. In Science, 2005
identified two proteins, NONO and WDR5, that can associate with the mammalian PER1 protein; data suggest that NONO probably operates antagonistically to PER proteins in mammalian cells, and that it is essential to normal circadian rhythmicity
The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs.
Impact
Carmichael et al., Farmington, United States. In Cell, 2001
This complex contains the inosine-specific RNA binding protein p54(nrb), the splicing factor PSF, and the inner nuclear matrix structural protein matrin 3. We provide evidence that one function of the complex identified here is to anchor hyperedited RNAs to the nuclear matrix, while allowing selectively edited mRNAs to be exported.
Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis.
Impact
Rosendaal et al., Leiden, Netherlands. In Lancet, 1995
The risk of thrombosis increased with increasing vWF or factor VIII concentration and was higher in subjects of non-O blood groups than in those of group O.
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