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Mitochondrial ribosomal protein L49

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p. [provided by RefSeq, May 2011] (from NCBI)
Top mentioned proteins: ACID, CAN, HAD, POLYMERASE, V1a
Papers on NOF
Secretome profiling of oral squamous cell carcinoma-associated fibroblasts reveals organization and disassembly of extracellular matrix and collagen metabolic process signatures.
Coletta et al., Piracicaba, Brazil. In Tumour Biol, Feb 2016
In this study, we searched for differences in the secretome of CAFs and normal oral fibroblasts (NOF) using mass spectrometry-based proteomics and biological network analysis.
Interplay of Multiple Interaction Forces: Binding of Norfloxacin to Human Serum Albumin.
Mukherjee et al., Bhopāl, India. In J Phys Chem B, Nov 2015
Herein, the binding interaction of a potential chemotherapeutic antibacterial drug norfloxacin (NOF) with a serum transport protein, human serum albumin (HSA), is investigated.
Expression Levels of the Oxidative Stress Response Gene ALDH3A2 in Granulosa-Lutein Cells Are Related to Female Age and Infertility Diagnosis.
Ávila et al., La Laguna, Spain. In Reprod Sci, Nov 2015
To investigate the effect of age on ALDH3A2 expression, 72 women between 18 and 44 years of age with no ovarian factor (NOF) were analyzed.
Wound healing potential of naringin ointment formulation via regulating the expression of inflammatory, apoptotic and growth mediators in experimental rats.
Bodhankar et al., Pune, India. In Pharm Biol, May 2015
AIM: The aim of this study is to evaluate the wound-healing activity of naringin ointment formulation (NOF) on experimental wound models.
Semantic Richness and Aging: The Effect of Number of Features in the Lexical Decision Task.
Rico Duarte et al., Bordeaux, France. In J Psycholinguist Res, Mar 2015
Semantic richness was investigated by manipulating the number of features of words (NOF), i.e., the number of characteristics that describe the meaning of words.
Functional characterisation of the osteoarthritis susceptibility locus at chromosome 6q14.1 marked by the polymorphism rs9350591.
Loughlin et al., Newcastle upon Tyne, United Kingdom. In Bmc Med Genet, 2014
METHODS: Total RNA was extracted from hip or knee cartilage of 161 OA patients and from hip cartilage of 29 non-OA patients who had undergone hip replacements as a result of neck-of-femur (NOF) fractures.
A diagnosis of giant cell-rich tumour of bone is supported by p63 immunohistochemistry, when more than 50 % of cells is stained.
Bouvier et al., Marseille, France. In Virchows Arch, 2014
We performed a multicentric retrospective study of 291 giant cell-rich tumours of bone which included 119 giant cell tumours of bone (GCTB), 76 aneurysmal bone cysts (ABC), 49 chondroblastomas (CB), 15 nonossifying fibromas (NOF), 10 giant cell reparative granulomas (RG) of jaws, 1 giant cell lesion of small bones, 2 hyperparathyroidism-related brown tumours (BT), 17 bone sarcomas with numerous osteoclasts and 2 malignant giant cell tumours of bone.
Interacting pairs in natural orbital functional theory.
Piris, San Sebastián, Spain. In J Chem Phys, 2014
An interacting-pair model is considered to attain a new natural orbital functional (NOF).
Binding interaction of a prospective chemotherapeutic antibacterial drug with β-lactoglobulin: results and challenges.
Mukherjee et al., Bhopāl, India. In Langmuir, 2014
This Article reports a detailed characterization of the binding interaction of a potential chemotherapeutic antibacterial drug, norfloxacin (NOF), with the mammalian milk protein β-lactoglobulin (βLG).
FB-NOF is a non-autonomous transposable element, expressed in Drosophila melanogaster and present only in the melanogaster group.
Cabré et al., Barcelona, Spain. In Gene, 2013
This is the case of the NOF sequences found in the FB of Drosophila melanogaster, formerly considered as an autonomous TE and currently proposed as part of the so-called FB-NOF element, the transposon that would be complete and fully functional.
Identification of the pathogenic pathways in osteoarthritic hip cartilage: commonality and discord between hip and knee OA.
Young et al., Newcastle upon Tyne, United Kingdom. In Osteoarthritis Cartilage, 2012
RESULTS: In total we identified 998 differentially expressed genes (fold change ≥ ±1.5, P-value ≤ 0.01) between neck of femur fracture (NOF) (n = 10) and OA hip (n = 9) patient cartilage.
The role of gicerin, a novel cell adhesion molecule, in development, regeneration and neoplasia.
Sasaki et al., Ōsaka, Japan. In Histol Histopathol, 2001
Neurite outgrowth factor (NOF) is an extracellular matrix (ECM) protein in the laminin family and its ligand, gicerin, is a novel cell adhesion molecule in the immunoglobulin superfamily.
[Functional analysis of a novel cell adhesion molecule, gicerin].
Taira, Ōsaka, Japan. In Nihon Yakurigaku Zasshi, 1999
Gicerin binds in a homophilic manner and also displays heterophilic binding activity to NOF (Neurite Outgrowth Factor), which belongs to the laminin family extracellular matrix molecule.
Peroxidative metabolism of carcinogenic N-arylhydroxamic acids: implications for tumorigenesis.
Ritter et al., Minneapolis, United States. In Environ Health Perspect, 1994
The metabolites formed in the presence of exogenous H2O2 are consistent with two peroxidative mechanisms: one electron-oxidation to a radical that dismutates to equimolar 2-nitrosofluorene (2-NOF) and the ester of the respective hydroxamic acid and halide-dependent oxidative cleavage, especially efficient in the presence of Br-, to equimolar 2-NOF and the respective acyl moiety.
Extracellular matrix proteins with neurite promoting activity and their receptors.
Miki et al., Ōsaka, Japan. In Neurosci Res, 1993
We have isolated a neurite outgrowth factor (NOF) which promotes neurite outgrowth from various neurons and belongs to laminin family, and also its receptor which is identified to be an immunoglobulin superfamily protein by cDNA cloning.
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