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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Atrophin 1

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-23 copies to 49-75 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein. [provided by RefSeq, Feb 2010] (from NCBI)
Top mentioned proteins: CAN, V1a, PrP, Insulin, HAD
Papers using NOD antibodies
Novel homo- and hemizygous mutations in EZH2 in myeloid malignancies
Saunthararajah Yogen et al., In Leukemia, 2009
... engraftment of human acute myeloid leukemia progenitor cells in beta 2-microglobulin-deficient NOD/SCID mice and in NOD/SCID mice transgenic for human growth factors ...
Sorting behavior of a transgenic erythropoietin-growth hormone fusion protein in murine salivary glands.
Chiorini John A., In PLoS ONE, 2007
... male eGFP donor cells allowed for the localization of Y-chromosome and eGFP cells in female NOD mice salivary tissue.Donors (CByB6F1-eGFP male) mice: male GFP transgenic mouse [C57BL/6-TgH (ACTbEGFP)10sb/J] (stock ...
A comprehensive review of interventions in the NOD mouse and implications for translation.
Maedler Kathrin, In PLoS ONE, 2004
... NOD and C57BL/6 mice were originally obtained from Bomholtgaard, Denmark and bred and maintained in the transgenic animal facility (UTCF) at ...
Transgenic Expression of Decoy Receptor 3 Protects Islets from Spontaneous and Chemical-induced Autoimmune Destruction in Nonobese Diabetic Mice
Sytwu Huey-Kang et al., In The Journal of Experimental Medicine, 2002
... a) was microinjected into the pronuclei of one-cell NOD embryos.Figure 1.Generation of transgenic mice ...
Proapoptotic BID is required for myeloid homeostasis and tumor suppression
Perlman Harris et al., In Arthritis Research & Therapy, 2002
... Non-obese diabetes (NOD) mice were purchased from Taconic (Germantown, NY, USA) and the homozygous KRN T-cell receptor transgenic mice (C57BL/6 background) were ...
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Papers on NOD
Impact of genetic variation on synaptic protein levels in genetically diverse mice.
Spijker et al., Amsterdam, Netherlands. In Proteomics, Feb 2016
Here we have used a panel of highly diverse inbred strains of mice-NOD/LtJ, A/J, 129S1/SvImJ, FVB/NJ, C57BL/6J, WSB/EiJ, PWK/PhJ and CAST/EiJ-to quantify the effects of genetic variation on the synaptic proteome between strains.
Activation of NLRP3 inflammasome enhances the proliferation and migration of A549 lung cancer cells.
Xie et al., Nanjing, China. In Oncol Rep, Feb 2016
Now, it is recognized that the nucleotide-binding and oligomerization domain (NOD) like receptors (NLRs)-containing inflammasomes are involved in cancer-related inflammation.
Disruption of CCL20-CCR6 interaction inhibits metastasis of advanced cutaneous T-cell lymphoma.
Tagawa et al., Akita, Japan. In Oncotarget, Feb 2016
Finally, to examine the in vivo effect of neutralizing CCL20 antibody, we used NOD/Shi-scid IL-2γnul mice inoculated with CTCL cells.
Mechanisms of autoimmunity in the NOD mouse: effector/regulatory cell equilibrium during peak inflammation.
Askenasy, Petah Tikva, Israel. In Immunology, Feb 2016
UNASSIGNED: Immune imbalance in autoimmune disorders such as type 1 diabetes (T1D) may originate from aberrant activities of effector cells or dysfunction of suppressor cells.
Combination antiretroviral studies for patients with primary biliary cirrhosis.
Mason et al., Edmonton, Canada. In World J Gastroenterol, Feb 2016
Nevertheless, viral mutants to lamivudine with zidovudine were later characterized in the NOD.c3c4 mouse model of PBC that has been used to test other antiretroviral regimens to betaretrovirus.
NOD-Like Receptors in Infection, Immunity, and Diseases.
Nahm et al., Wŏnju, South Korea. In Yonsei Med J, Jan 2016
Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) are pattern-recognition receptors similar to toll-like receptors (TLRs).
Innate immunity in diabetes and diabetic nephropathy.
Makino et al., Okayama, Japan. In Nat Rev Nephrol, Jan 2016
The innate immune system includes several classes of pattern recognition receptors (PRRs), including membrane-bound Toll-like receptors (TLRs) and nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs).
Postnatal Hematopoiesis and Gut Microbiota in NOD Mice Deviate from C57BL/6 Mice.
Frøkiær et al., Frederiksberg, Denmark. In J Diabetes Res, Dec 2015
The nonobese diabetic (NOD) mouse spontaneously develops autoimmune diabetes, but neonatal studies of NOD mice are lacking.
Microarray and whole-exome sequencing analysis of familial Behçet's disease patients.
Nojima et al., Suita, Japan. In Sci Rep, Dec 2015
They include heterozygous SNVs in the genes encoding IL-1 receptor-associated kinase 4 (IRAK4), nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain-containing 14 (NRP14) and melanoma antigen-encoding gene E2 (MAGEE2); IRAK4 harbors a missense mutation, whereas NRP14 and MAGEE2 harbor nonsense mutations.
Oxidative stress inhibits distant metastasis by human melanoma cells.
Morrison et al., Dallas, United States. In Nature, Dec 2015
Here we studied human melanomas that differed in their metastasis histories in patients and in their capacity to metastasize in NOD-SCID-Il2rg(-/-) (NSG) mice.
Does Infection-Induced Immune Activation Contribute to Dementia?
Dal-Pizzol et al., Houston, United States. In Aging Dis, Sep 2015
Examples of PRR include toll-like receptors (TLR), receptors for advanced glycation endproducts (RAGE), nucleotide binding oligomerisation domain (NOD)-like receptors (NLR), c-type lectin receptors (CLR), RIG-I-like receptors (RLR), and intra-cytosolic DNA sensors.
Clinical Utility of Patient-Derived Xenografts to Determine Biomarkers of Prognosis and Map Resistance Pathways in EGFR-Mutant Lung Adenocarcinoma.
Tsao et al., Toronto, Canada. In J Clin Oncol, Sep 2015
METHODS: Surgically resected early-stage non-small-cell lung carcinoma (NSCLC) tumors were implanted into nonobese diabetic severe combined immune deficient (NOD-SCID) mice.
Receptor-mediated exopolysaccharide perception controls bacterial infection.
Stougaard et al., Århus, Denmark. In Nature, Aug 2015
Finally, we show that Epr3 expression is inducible and dependent on host perception of bacterial nodulation (Nod) factors.
The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells.
Kanneganti et al., Memphis, United States. In Immunity, May 2015
Missense mutations in the nucleotide-binding oligomerization domain (NOD)-like receptor pyrin domain containing family of gene 12 (Nlrp12) are associated with periodic fever syndromes and atopic dermatitis in humans.
Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway.
Stankovic et al., Waltham, United States. In Lancet, Mar 2015
Primary CLL cells with biallelic TP53 or ATM inactivation were xenotransplanted into NOD/Shi-scid/IL-2Rγ mice.
Dentatorubral-pallidoluysian atrophy: haplotype of Asian origin in 2 Italian families.
Savettieri et al., In Mov Disord, 2012
This study demonistrated that Atn1 is response for Dentatorubral-pallidoluysian atrophy.
Dentatorubral-pallidoluysian atrophy.
Tsuji, Tokyo, Japan. In Handb Clin Neurol, 2011
This sttudy suggested that age-dependent and CAG repeat-dependent intranuclear accumulation of mutant DRPLA leading to nuclear dysfunctions are suggested to be the essential pathophysiologic mechanisms in Dentatorubral-pallidoluysian atrophy.
Differential clinical features in a pair of monozygotic twins with dentatorubropallidoluysian atrophy.
Yamamoto et al., In Eur J Neurol, 2011
A pair of monozygotic twins is diagnosed with dentatorubro pallidoluysian atrophy, identical CAG repeats, and different clinical courses.
Proteolytic processing regulates pathological accumulation in dentatorubral-pallidoluysian atrophy.
Yazawa et al., Japan. In Febs J, 2010
the C-terminal fragment plays a principal role in the pathological accumulation of ATN1 in dentatorubral-pallidoluysian atrophy
Long-term disability and prognosis in dentatorubral-pallidoluysian atrophy: a correlation with CAG repeat length.
Onodera et al., Niigata, Japan. In Mov Disord, 2010
The CAG repeat length of DRPLA may have a considerable effect on not only the disease onset but also the disease milestones and prognosis in DRPLA patients.
More papers using NOD antibodies
Rapid and simple phenotypic assay for drug susceptibility of human immunodeficiency virus type 1 using CCR5-expressing HeLa/CD4+ cell clone 1–10 (MAGIC-5)
Speck Roberto F., In PLoS ONE, 2000
... The NOD/SCID/B51Tg mice were established by backcrossing NOD/SCID mice with HLA-B*51:01 transgenic C3H/HeJ mice ...
The instructive role of innate immunity in the acquired immune response
Monteiro Renato C. et al., In The Journal of Experimental Medicine, 1995
... Electroeluted DNA was microinjected into fertilized NOD eggs, and transgenic mice were identified by ...
Lysosulfatide (galactosylsphingosine-3-O-sulfate) from metachromatic leukodystrophy and normal human brain.
Sandberg Johan K., In PLoS ONE, 1988
... NOD mice were also purchased from The Jackson Laboratory/Taconic Farms and kept under specific pathogen-free conditions in our colony at the Torrey Pines Institute for Molecular Studies ...
Distribution and release of human pancreatic polypeptide
Sandler Stellan et al., In Experimental Diabetes Research, 1975
... Inbred NOD mice (Biomedical Center, Uppsala, Sweden), originally ...
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