[Regulatory effects of cyclosporin A and tacrolimus on the immunological gene expressions in renal transplant recipients].
Beijing, China. In Zhongguo Yi Xue Ke Xue Yuan Xue Bao, 2012
RESULTS: The TLR4, CEBPB, IL4R, IL1R1,IL18R1,and IL1R2 genes were remarkably upregulated, whereas IL-2, CCL5, CD27, CCR5, CCR4, CD4, RPL13A, TGFB3, CD86, CCR3, STAT1, NFATC2IP, IL23A, IL15, IRF4, and TFCP2 were downregulated 24 hours after CsA treatment.
Arginine methylation regulates the cytokine response.
Montréal, Canada. In Mol Cell, 2004
The recent identification of the NFAT-interacting protein NIP45 as a methylated protein by marks a new role for protein arginine methylation in lymphocyte signaling and cytokine gene activation.