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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Ninein

Nin, hNinein
This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, NOD, HAD, NOB1, ACID
Papers on Nin
miR-192 suppresses the tumorigenicity of prostate cancer cells by targeting and inhibiting nin one binding protein.
New
Huo et al., Luoyang, China. In Int J Mol Med, Feb 2016
UNASSIGNED: Nin one binding (NOB1) protein has been identified as an oncogene in various human cancers, including prostate cancer.
Chitinase-resistant hydrophilic symbiotic factors secreted by Frankia activate both Ca(2+) spiking and NIN gene expression in the actinorhizal plant Casuarina glauca.
New
Svistoonoff et al., France. In New Phytol, Jan 2016
Although it is now well-established that decorated lipo-chitooligosaccharide Nod factors are the key rhizobial signals which initiate infection/nodulation in host legume species, the identity of the equivalent microbial signaling molecules in the Frankia/actinorhizal association remains elusive.
The NIN Transcription Factor Coordinates Diverse Nodulation Programs in Different Tissues of the Medicago truncatula Root.
New
Oldroyd et al., Norwich, United Kingdom. In Plant Cell, Dec 2015
We show that while early Nod factor signaling associated with calcium oscillations is limited to the root surface, the resultant activation of Nodule Inception (NIN) in the root epidermis is sufficient to promote cytokinin signaling and nodule organogenesis in the inner root cortex.
Association of Chicken Growth Hormones and Insulin-like Growth Factor Gene Polymorphisms with Growth Performance and Carcass Traits in Thai Broilers.
New
Duangjinda et al., Khon Kaen, Thailand. In Asian-australas J Anim Sci, Dec 2015
The crossbreds from commercial parent stock (PS) broilers with four Thai synthetic breeds; Kaen Thong (KT), Khai Mook Esarn (KM), Soi Nin (SN), and Soi Pet (SP) were used to study the association among chicken growth hormones (cGH) and the insulin-like growth factor (IGF-I) genes for growth and carcass traits; for the purpose of developing a suitable terminal breeding program for Thai broilers.
SCARN a Novel Class of SCAR Protein That Is Required for Root-Hair Infection during Legume Nodulation.
New
Xie et al., Shanghai, China. In Plos Genet, Oct 2015
In addition, we found that SCARN expression is enhanced by M. loti in epidermal cells and that this is directly regulated by the NODULE INCEPTION (NIN) transcription factor.
Determining the N-terminal orientations of recombinant transmembrane proteins in the Escherichia coli plasma membrane.
Wang et al., Taipei, Taiwan. In Sci Rep, 2014
D94N, the mutant of bacteriorhodopsin from Haloarcula marismortui, can be a fusion partner to increase the production of the target TM proteins if their N-termini are in cytoplasm (Nin orientation).
Emergence of a new step towards understanding the molecular mechanisms underlying nitrate-regulated gene expression.
Review
Yanagisawa et al., Tokyo, Japan. In J Exp Bot, 2014
A key finding is the identification of NIN-like proteins (NLPs) as transcription factors governing nitrate-inducible gene expression.
The plant RWP-RK transcription factors: key regulators of nitrogen responses and of gametophyte development.
Review
Krapp et al., Versailles, France. In J Exp Bot, 2014
Based on phylogenetic and domain analyses, we classified the RWP-RK proteins of six different species in two subfamilies: the NIN-like proteins (NLPs), which carry an additional PB1 domain at their C-terminus, and the RWP-RK domain proteins (RKDs), which are divided into three subgroups.
Mechanisms of "kidney governing bones" theory in traditional Chinese medicine.
Review
Wang et al., Beijing, China. In Front Med, 2014
(1) Neuroendocrine-immune network (NIN)-osteoclast regulatory pathway OPG-RANKL-RANK is one of the mechanisms of "kidney governing bones."
Nitrate transport and signalling in Arabidopsis.
Review
Daniel-Vedele et al., Versailles, France. In J Exp Bot, 2014
The recent discovery of the NIN-like proteins as master regulators for nitrate signalling has led to a new understanding of the regulation cascade.
Practical considerations for conducting ecotoxicity test methods with manufactured nanomaterials: what have we learnt so far?
Review
Riediker et al., Plymouth, United Kingdom. In Ecotoxicology, 2012
This review paper reports the consensus of a technical workshop hosted by the European network, NanoImpactNet (NIN).
Autoimmunity against hNinein, a human centrosomal protein, in patients with rheumatoid arthritis and systemic lupus erythematosus.
GeneRIF
Hong et al., Kao-hsiung, Taiwan. In Mol Med Report, 2011
The prevalence of hNinein autoreactivity and its specificity in 22 rheumatoid arthritis and 32 systemic lupus erythematosus autoimmune disease sera.
Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.
GeneRIF
Inagaki et al., Nagoya, Japan. In J Cell Sci, 2011
Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein.
Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.
GeneRIF
McWilliams et al., Rochester, United States. In Cancer Epidemiol Biomarkers Prev, 2010
Two single nucleotide polymorphisms in the APC and NIN loci were significantly associated with pancreatic cancer risk
Relocalization of a microtubule-anchoring protein, ninein, from the centrosome to dendrites during differentiation of mouse neurons.
GeneRIF
Hayashi et al., Tokyo, Japan. In Histochem Cell Biol, 2009
ninein is localized at the centrosome in undifferentiated neural precursors; but ninein was barely detected in migrating neurons, such as those in the intermediate layer of the cerebral cortex and the internal granular layer of the cerebellar cortex
Ninein is released from the centrosome and moves bi-directionally along microtubules.
GeneRIF
Mogensen et al., Norwich, United Kingdom. In J Cell Sci, 2007
Data show that ninein is highly dynamic and that, in epithelial cells, it is present not only at the centrosome but also in the cytoplasm as distinct speckles.
A cytokinin perception mutant colonized by Rhizobium in the absence of nodule organogenesis.
Impact
Szczyglowski et al., London, Canada. In Science, 2007
We demonstrated that the corresponding gene encodes a cytokinin receptor that is required for the activation of the nodule inception regulator Nin and nodule organogenesis.
A plant regulator controlling development of symbiotic root nodules.
Impact
Stougaard et al., Århus, Denmark. In Nature, 1999
To identify the regulatory components that act early in nodule induction, we characterized a transposon-tagged Lotus japonicus mutant, nin (for nodule inception), arrested at the stage of bacterial recognition.
Fine-tuning the topology of a polytopic membrane protein: role of positively and negatively charged amino acids.
Impact
von Heijne et al., Huddinge, Sweden. In Cell, 1990
We show that addition or removal of as little as a single positively charged lysine residue in one of two critical regions can be sufficient to reverse the transmembrane topology of the molecule from Nout-Cout to Nin-Cin.
Control of topology and mode of assembly of a polytopic membrane protein by positively charged residues.
Impact
von Heijne, Huddinge, Sweden. In Nature, 1989
I now describe a derivative of Escherichia coli leader peptidase, a polytopic inner-membrane protein, that switches from sec-gene-dependent membrane insertion with a Nout-Cout transmembrane topology to sec-gene-independent insertion with a Nin-Cin topology in response to the addition of four positively charged lysines to its N terminus.
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