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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Transmembrane protein 8B

NGX6, Nasopharyngeal carcinoma-associated gene 6, nag5
Top mentioned proteins: CAN, Epidermal Growth Factor, HAD, Ezrin, GAP
Papers on NGX6
Correlation of NGX6 expression with clinicopathologic features and prognosis in colon cancer.
Liu et al., Changsha, China. In Int J Clin Exp Med, 2014
OBJECTIVE: The aim was to explore the correlation of NGX6 expression with clinicopathological features and prognosis in colon cancer.
Association of ultrasonographic features with NGX6 expression and prognosis in invasive ductal breast carcinoma.
Zhu et al., Changsha, China. In Int J Clin Exp Pathol, 2014
INTRODUCTION: Nasopharyngeal carcinoma-associated gene 6 (NGX6) is a newly discovered tumor suppressor gene.
DNA promoter and histone H3 methylation downregulate NGX6 in gastric cancer cells.
Dai et al., Shenyang, China. In Med Oncol, 2014
Nasopharyngeal carcinoma-associated gene 6 (NGX6) is a novel candidate tumor metastasis suppressor gene.
Egr-1 regulates the transcription of NGX6 gene through a Sp1/Egr-1 overlapping site in the promoter.
Li et al., Zhuzhou, China. In Bmc Mol Biol, 2013
BACKGROUND: As a novel candidate metastasis suppressor gene, Nasopharyngeal carcinoma-associated gene 6 (NGX6) is involved in cellular growth, cell cycle progression and tumor angiogenesis.
NGX6 expression improves the sensitivity of tamoxifen-resistant MCF-7 cells through modulation of the Smad signaling pathway.
Wang et al., Shenyang, China. In Int J Oncol, 2013
The effects of nasopharyngeal carcinoma-associated gene 6 (NGX6) in breast cancer was studied.
Evaluation of UDP-glucuronosyltransferase 2B17 (UGT2B17) and dihydrofolate reductase (DHFR) genes deletion and the expression level of NGX6 mRNA in breast cancer.
Taheri et al., Zāhedān, Iran. In Mol Biol Rep, 2012
The present study was aimed to investigate the possible association between 19-base pair (bp) deletion polymorphism of the DHFR gene (rs70991108), null genotype of UDP-glucuronosyltransferase 2B17 (UGT2B17) as well as the expression level of nasopharyngeal carcinoma-associated gene 6 (NGX6) with the risk of breast cancer.
Reveals new lung adenocarcinoma cancer genes based on gene expression.
Zhen et al., Shanghai, China. In Eur Rev Med Pharmacol Sci, 2012
Further, we predicted genes including EGF-like domain might be the potential target genes for further study, such as NGX6, MUC17, and Nel.
Tumor suppressor gene NGX6 induces changes in protein expression profiles in colon cancer HT-29 cells.
GeneRIF
Su et al., Changsha, China. In Acta Biochim Biophys Sin (shanghai), 2012
Data suggest that nasopharyngeal carcinoma-associated gene 6 (NGX6) may inhibit colon cancer through the regulation of proteins involved in cell proliferation, metastasis, apoptosis, cytoskeletal structure, metabolism, and signal transduction.
[Transcriptomic regulation and molecular mechanism of polygenic tumor at different stages].
Review
Li et al., Changsha, China. In Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2011
Genes including SPLUNC1, LTF, BRD7, NOR1, BRCA1/2, PALB2, AF1Q, SOX17, NGX6, SOX7, and LRRC4 have been identified as the key transcriptional regulation genes during the stage of tumor initiation and invasion.
[Role of NGX6 in Wnt/β-catenin signaling pathway in colon cancer].
GeneRIF
Liu et al., Changsha, China. In Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2011
NGX6 could inhibit the expression of Wnt signaling downstream target genes in colon cancer.
Differential miRNA expression and their target genes between NGX6-positive and negative colon cancer cells.
GeneRIF
Shen et al., Changsha, China. In Mol Cell Biochem, 2010
NGX6 plays an important role in regulation of apoptosis, mobility/migration, and hydrolase as well as activity of JNK and Notch pathways through NGX6-mediated miRNA expression
NGX6 inhibits cell invasion and adhesion through suppression of Wnt/beta-catenin signal pathway in colon cancer.
GeneRIF
Wang et al., Changsha, China. In Acta Biochim Biophys Sin (shanghai), 2010
Data show that NGX6 could suppress the translocation of beta-catenin from nucleus and cytoplasm to plasma membrane, inhibit the activity of TCF4 transcript factor, and down-regulate the expression of Wnt-direct-targeted genes.
Expression of 2 transcripts of NGX6 gene in colorectal cancer and the correlation with carcinoembryonic antigen.
GeneRIF
Li et al., Changsha, China. In Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2010
The short transcript of NGX6 play an important role in colorectal cancer, and reduced expression may contribute to metastasis.
NGX6 gene mediated by promoter methylation as a potential molecular marker in colorectal cancer.
GeneRIF
Li et al., Changsha, China. In Bmc Cancer, 2009
Down-regulation of NGX6 gene is related to the promoter methylation. DNA methylation of NGX6 promoter might be a potential molecular marker for diagnosis or prognosis, or serve as a therapeutic target in colorectal cancer.
[Functional genomics of nasopharyngeal carcinoma susceptibility/suppressor gene].
Review
Li et al., Changsha, China. In Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2008
The functional research of NPC susceptibility/ suppressor gene candidates indicated: (1) The increased expression of Cx contributed to obstacles of gap junctional intercellular communication (GJIC), and resulted an aberration of GJIC; (2) BRD7, a transcript factor, was associated with cell cycle regulation; (3) NAG7,an estrogen receptor repressor, inhibited the invasive potential of human NPC cells by regulating ERalpha expression and the H-ras/p-c-Raf and JNK/AP-1/MMP1 signaling pathways; (4) NGX6, a metastasis-associated protein, can negative-regulate EGF/Ras/MAPK signaling transduction pathway, and interact with ezrin protein to inhibit invasion and metastasis of NPC cells; (5) SPLUNC1, a secreted protein, can inhibit the bacterium clone formation, and is an innate immune molecule.
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